The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest

Molecular and Cellular Biology

Volumn 35, Issue 7, 2015, Pages 1254-1268

  von Stechow, Louise ^a   Typas, Dimitris ^b   Puigvert, Jordi Carreras ^a,b   Oort, Laurens ^a   Siddappa, Ramakrishnaiah ^a   Pines, Alex ^b   Vrieling, Harry ^b   van de Water, Bob ^a   Mullenders, Leon H F ^b   Danen, Erik H J ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARIADNE HOMOLOGUE 1 PROTEIN; CASPASE 3; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INITIATION FACTOR 4A; INITIATION FACTOR 4E; INITIATION FACTOR 4G; MESSENGER RNA; PROTEIN P53; REPLICATION FACTOR A; SMALL INTERFERING RNA; TUBULIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ARIH1 PROTEIN, HUMAN; ARIH1 PROTEIN, MOUSE; CAP BINDING PROTEIN; CARRIER PROTEIN; EIF4E2 PROTEIN, HUMAN; EIF4E2 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; CANCER CELL; DNA DAMAGE; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IONIZING RADIATION; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIBOSOME; RNA INTERFERENCE; RNA TRANSLATION; SARCOMA; UBIQUITINATION; WESTERN BLOTTING; WILD TYPE; ANIMAL; CELL LINE; EMBRYONIC STEM CELL; GENETICS; METABOLISM; PROTEIN SYNTHESIS; TUMOR CELL LINE;

EUKARYOTA;

ANIMALS; CARRIER PROTEINS; CASPASE 3; CELL LINE; CELL LINE, TUMOR; DNA DAMAGE; EMBRYONIC STEM CELLS; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; MICE; PROTEIN BIOSYNTHESIS; RNA CAP-BINDING PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84924860228     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01152-14     Document Type: Article

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