α-tomatine inhibits growth and induces apoptosis in HL-60 human myeloid leukemia cells

Molecular Medicine Reports

Volumn 11, Issue 6, 2015, Pages 4573-4578

  Huang, Huarong ^a,b   Chen, Shaohua ^c   Van Doren, Jeremiah ^b   Li, Dongli ^a   Farichon, Chelsea ^b   He, Yan ^a   Zhang, Qiuyan ^a   Zhang, Kun ^a   Conney, Allan H ^a,b   Goodin, Susan ^d   Du, Zhiyun ^a   Zheng, Xi ^a,b  

^a GUANGDONG UNIVERSITY OF TECHNOLOGY   (China)

^b RUTGERS UNIVERSITY   (United States)

^c GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^d RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

Apoptosis; Cholesterol; Glycoalkaloid; Growth inhibition; Leukemia; tomatine

Indexed keywords

LENTIVIRUS VECTOR; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN BID; PROTEIN KINASE B; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR CLOCK; ALPHA-TOMATINE; CHOLESTEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; TOMATINE;

ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER SIZE; CELL LEVEL; CELL PROLIFERATION; CELL VIABILITY; CIRCADIAN RHYTHM; COLORECTAL CANCER CELL LINE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN FUNCTION; RNA INTERFERENCE; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BODY WEIGHT; CHEMISTRY; DRUG EFFECTS; HL 60 CELL LINE; LEUKEMIA, MYELOID; METABOLISM; PATHOLOGY; SCID MOUSE; XENOGRAFT;

ANIMALIA; LYCOPERSICON ESCULENTUM; MUS;

ANIMALS; APOPTOSIS; BODY WEIGHT; CELL PROLIFERATION; CHOLESTEROL; FEMALE; HL-60 CELLS; HUMANS; LEUKEMIA, MYELOID; MICE; MICE, SCID; NF-KAPPA B; TETRADECANOYLPHORBOL ACETATE; TOMATINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84924750669     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3238     Document Type: Article

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