α-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Chao, Min Wu ^a   Chen, Chun Han ^a   Chang, Ya Ling ^a   Teng, Che Ming ^a   Pan, Shiow Lin ^b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE; PACLITAXEL; PROTEIN BAK; PROTEIN MCL 1; PROTEIN MCL 1S; SURVIVIN; TOMATINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; EX VIVO STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TRANSPORT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CASPASES; CELL CYCLE; CELL NUCLEUS; DOWN-REGULATION; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; K562 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, SCID; NEOPLASM PROTEINS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TOMATINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

LYCOPERSICON ESCULENTUM; MUS;

EID: 84866099730     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044093     Document Type: Article

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