메뉴 건너뛰기




Volumn 12, Issue 1, 2015, Pages 4-14

Platelets in the Alzheimer's disease brain: Do they play a role in cerebral amyloid angiopathy?

Author keywords

Alzheimer; Migration; Platelet; Postmortem; Vessel

Indexed keywords

FIBRINOGEN RECEPTOR; PADGEM PROTEIN; AMYLOID PRECURSOR PROTEIN; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; GLYCOPROTEIN IIB; ORGANIC COMPOUND; PKH 26;

EID: 84924704970     PISSN: 15672026     EISSN: 18755739     Source Type: Journal    
DOI: 10.2174/1567202612666150102124703     Document Type: Article
Times cited : (26)

References (59)
  • 1
    • 77649088906 scopus 로고    scopus 로고
    • Role of platelets in neuroinflammation: A wide-angle perspective
    • Horstman LL, Jy W, Ahn YS, et al. Role of platelets in neuroinflammation: a wide-angle perspective. J Neuroinfallmation 2010; 3; 7: 10.
    • (2010) J Neuroinfallmation , vol.3 , Issue.7 , pp. 10
    • Horstman, L.L.1    Jy, W.2    Ahn, Y.S.3
  • 2
    • 79952701977 scopus 로고    scopus 로고
    • Chronic mild cerebrovascular dysfunction as a cause for Alzheimers disease?
    • Humpel C. Chronic mild cerebrovascular dysfunction as a cause for Alzheimers disease? Exp Gerontol 2011; 46 (4): 225-32.
    • (2011) Exp Gerontol , vol.46 , Issue.4 , pp. 225-232
    • Humpel, C.1
  • 3
    • 2342614850 scopus 로고    scopus 로고
    • Neurovascular regulation in the normal brain and in Alzheimer's disease
    • Iadecola C. Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat Rev Neurosci 2004; 5 (5): 347-360.
    • (2004) Nat Rev Neurosci , vol.5 , Issue.5 , pp. 347-360
    • Iadecola, C.1
  • 4
    • 0036218738 scopus 로고    scopus 로고
    • Alzheimer's disease as a vascular disorder
    • De la Torre J.C. Alzheimer's disease as a vascular disorder. Stroke 2000; 33: 1152-1162.
    • (2000) Stroke , vol.33 , pp. 1152-1162
    • De La Torre, J.C.1
  • 6
    • 84911431191 scopus 로고    scopus 로고
    • Platelets as potential link between diabetes and Alzheimer's disease
    • Randriamboavonjy V, Sopova K, Stellos K, Laske C. Platelets as potential link between diabetes and Alzheimer's disease. Curr Alzheimer Res 2014; 11 (9): 862-8.
    • (2014) Curr Alzheimer Res , vol.11 , Issue.9 , pp. 862-868
    • Randriamboavonjy, V.1    Sopova, K.2    Stellos, K.3    Laske, C.4
  • 7
    • 84899492302 scopus 로고    scopus 로고
    • Contribution of blood platelets to vascular pathology in Alzheimer's disease
    • Zhang W, Huang W, Jing F. Contribution of blood platelets to vascular pathology in Alzheimer's disease. J Blood Med 2013; 4: 141-7.
    • (2013) J Blood Med , vol.4 , pp. 141-147
    • Zhang, W.1    Huang, W.2    Jing, F.3
  • 8
    • 84903128278 scopus 로고    scopus 로고
    • Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer's disease
    • Jarre A, Gowert NS, Donner L, et al. Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer's disease. Cell Signal 2014; 26 (9): 2040-50.
    • (2014) Cell Signal , vol.26 , Issue.9 , pp. 2040-2050
    • Jarre, A.1    Gowert, N.S.2    Donner, L.3
  • 9
    • 0036323445 scopus 로고    scopus 로고
    • Alzheimers disease and cerebrovascular pathology: An update
    • Jellinger KA. Alzheimers disease and cerebrovascular pathology: an update. J Neural Transm 2002; 109 (5-6): 813-836.
    • (2002) J Neural Transm , vol.109 , Issue.5-6 , pp. 813-836
    • Jellinger, K.A.1
  • 10
    • 84887003951 scopus 로고    scopus 로고
    • Platelets and neurovascular inflammation
    • Langer HF, Chavakis T. Platelets and neurovascular inflammation. Thromb Haemost. 2013; 110 (5): 888-93.
    • (2013) Thromb Haemost , vol.110 , Issue.5 , pp. 888-893
    • Langer, H.F.1    Chavakis, T.2
  • 11
    • 84896292803 scopus 로고    scopus 로고
    • Blood platelets in the progression of Alzheimer's disease
    • Gowert NS, Donner L, Chatterjee M, et al. Blood platelets in the progression of Alzheimer's disease. PLoS One 2014; 9 (2): e90523.
    • (2014) PLoS One , vol.9 , Issue.2 , pp. e90523
    • Gowert, N.S.1    Donner, L.2    Chatterjee, M.3
  • 12
    • 84910096223 scopus 로고    scopus 로고
    • Alzheimer and platelets: Low-density platelet populations reveal increased serotonin content in Alzheimer type dementia
    • Milovanovic M, Eriksson K, Winblad B, et al. Alzheimer and platelets: low-density platelet populations reveal increased serotonin content in Alzheimer type dementia. Clin biochem 2014; 47 (15): 51-3.
    • (2014) Clin Biochem , vol.47 , Issue.15 , pp. 51-53
    • Milovanovic, M.1    Eriksson, K.2    Winblad, B.3
  • 13
    • 0242267132 scopus 로고    scopus 로고
    • Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets
    • Evin G, Zhu A, Holsinger RM, Masters CL, Li QX. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets. Neurosci Res 2003; 74 (3): 386-92.
    • (2003) Neurosci Res , vol.74 , Issue.3 , pp. 386-392
    • Evin, G.1    Zhu, A.2    Holsinger, R.M.3    Masters, C.L.4    Li, Q.X.5
  • 16
    • 84873534190 scopus 로고    scopus 로고
    • Impact of gender on platelet membrane functions of Alzheimer's disease patients
    • Vignini A, Giusti L, Raffaeli F, et al. Impact of gender on platelet membrane functions of Alzheimer's disease patients. Exp Gerontol 2013; 48 (3): 319-25.
    • (2013) Exp Gerontol , vol.48 , Issue.3 , pp. 319-325
    • Vignini, A.1    Giusti, L.2    Raffaeli, F.3
  • 17
    • 0029819924 scopus 로고    scopus 로고
    • Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome
    • Di Luca M, Pastorino L, Cattabeni F, et al. Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome. Arch Neurol 1996; 53 (11): 1162-6.
    • (1996) Arch Neurol , vol.53 , Issue.11 , pp. 1162-1166
    • Di Luca, M.1    Pastorino, L.2    Cattabeni, F.3
  • 18
    • 0031721665 scopus 로고    scopus 로고
    • Differential level of platelet amyloid beta precursor protein isoforms: An early marker for Alzheimer disease
    • Di Luca M, Pastorino L, Bianchetti A, et al. Differential level of platelet amyloid beta precursor protein isoforms: an early marker for Alzheimer disease. Arch Neurol 1998; 55 (9): 1195-200.
    • (1998) Arch Neurol , vol.55 , Issue.9 , pp. 1195-1200
    • Di Luca, M.1    Pastorino, L.2    Bianchetti, A.3
  • 19
    • 84907212853 scopus 로고    scopus 로고
    • A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis
    • Rakesh KS, Jagadish S, Vinayaka AC, et al. A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis. PLoS One. 2014; 9 (9): e107182.
    • (2014) PLoS One , vol.9 , Issue.9 , pp. e107182
    • Rakesh, K.S.1    Jagadish, S.2    Vinayaka, A.C.3
  • 20
    • 33645891450 scopus 로고    scopus 로고
    • Transplantation of NGF secreting primary monocytes counteracts NMDA-induced cell death of rat cholinergic neurons in vivo
    • Zassler B, Humpel C. Transplantation of NGF secreting primary monocytes counteracts NMDA-induced cell death of rat cholinergic neurons in vivo. Exp Neurol 2006; 198 (2): 391-400.
    • (2006) Exp Neurol , vol.198 , Issue.2 , pp. 391-400
    • Zassler, B.1    Humpel, C.2
  • 21
    • 84901953782 scopus 로고    scopus 로고
    • Platelet-derived nerve growth factor supports the survival of cholinergic neurons in organotypic rat brain slices
    • Kniewallner KM, Grimm N, Humpel C. Platelet-derived nerve growth factor supports the survival of cholinergic neurons in organotypic rat brain slices, Neurosci Lett 2014; 574: 64-9.
    • (2014) Neurosci Lett , vol.574 , pp. 64-69
    • Kniewallner, K.M.1    Grimm, N.2    Humpel, C.3
  • 22
    • 2442594971 scopus 로고    scopus 로고
    • Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor
    • Davis J, Xu F, Deane R, et al. Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor. J Biol Chem. 2004; 279 (19): 20296-306.
    • (2004) J Biol Chem , vol.279 , Issue.19 , pp. 20296-20306
    • Davis, J.1    Xu, F.2    Deane, R.3
  • 23
    • 0026079843 scopus 로고
    • Biochemical characterization of PECAM-1 (CD31 antigen) on human platelets
    • Metzelaar MJ, Korteweg J, Sixma JJ, Nieuwenhuis HK. Biochemical characterization of PECAM-1 (CD31 antigen) on human platelets. Thromb Haemost 1991; 66 (6): 700-7.
    • (1991) Thromb Haemost , vol.66 , Issue.6 , pp. 700-707
    • Metzelaar, M.J.1    Korteweg, J.2    Sixma, J.J.3    Nieuwenhuis, H.K.4
  • 24
    • 37549049311 scopus 로고    scopus 로고
    • Molecular characterization and expression analysis of the gene coding for the porcine beta (3) integrin subunit (CD61)
    • Jiménez-Marín A, Yubero N, Esteso G, et al. Molecular characterization and expression analysis of the gene coding for the porcine beta (3) integrin subunit (CD61). Gene 2008; 408 (1-2): 9-17.
    • (2008) Gene , vol.408 , Issue.1-2 , pp. 9-17
    • Jiménez-Marín, A.1    Yubero, N.2    Esteso, G.3
  • 25
    • 84904568806 scopus 로고    scopus 로고
    • Activated platelets from diabetic rats cause endothelial dysfunction by decreasing Akt/endothelial NO synthase signaling pathway
    • Ishida K, Taguchi K, Matsumoto T, Kobayashi T. Activated platelets from diabetic rats cause endothelial dysfunction by decreasing Akt/endothelial NO synthase signaling pathway. Plos One 2014; 9 (7): e102310.
    • (2014) Plos One , vol.9 , Issue.7 , pp. e102310
    • Ishida, K.1    Taguchi, K.2    Matsumoto, T.3    Kobayashi, T.4
  • 26
    • 34648826777 scopus 로고    scopus 로고
    • Dynamic visualization of thrombopoiesis within bone marrow
    • Junt T, Schulze H, Chen Z, et al. Dynamic visualization of thrombopoiesis within bone marrow. Science 2007; 317 (5845): 1767-70.
    • (2007) Science , vol.317 , Issue.5845 , pp. 1767-1770
    • Junt, T.1    Schulze, H.2    Chen, Z.3
  • 28
    • 33846326297 scopus 로고    scopus 로고
    • [The enigma of arrival: [Corrected] the entrance of auto-immune T lymphocytes in central nervous tissues and of their attack against the myelin structures]
    • Wekerle H. [The enigma of arrival: [corrected] the entrance of auto-immune T lymphocytes in central nervous tissues and of their attack against the myelin structures]. C R Biol 2007; 330 (1): 1-12.
    • (2007) C R Biol , vol.330 , Issue.1 , pp. 1-12
    • Wekerle, H.1
  • 29
    • 84885345875 scopus 로고    scopus 로고
    • Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration
    • Lampron, A., Pimentel-Coelho, P.M., Rivest, S. Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration. J Comparative Neurol 2013; 521 (17): 3863-3876.
    • (2013) J Comparative Neurol , vol.521 , Issue.17 , pp. 3863-3876
    • Lampron, A.1    Pimentel-Coelho, P.M.2    Rivest, S.3
  • 30
    • 80355146868 scopus 로고    scopus 로고
    • Monocyte recruitment during infection and inflammation
    • Shi, C., Pamer, E.G. Monocyte recruitment during infection and inflammation. Nat Rev Immunol 2011; 11: 762-774.
    • (2011) Nat Rev Immunol , vol.11 , pp. 762-774
    • Shi, C.1    Pamer, E.G.2
  • 31
    • 0036200984 scopus 로고    scopus 로고
    • Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases
    • Togo, T., Akiyama, H., Iseki, E., et al. Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases. J Neuroimmunol 2002; 124 (1-2): 83-92.
    • (2002) J Neuroimmunol , vol.124 , Issue.1-2 , pp. 83-92
    • Togo, T.1    Akiyama, H.2    Iseki, E.3
  • 32
    • 0025981021 scopus 로고
    • Kimura. T-lymphocyte entry into the central nervous system
    • Hickey WF, Hsu BL, Kimura. T-lymphocyte entry into the central nervous system. J Neurosci Res 1991; 28 (2): 254-260.
    • (1991) J Neurosci Res , vol.28 , Issue.2 , pp. 254-260
    • Hickey, W.F.1    Hsu, B.L.2
  • 33
    • 77954851584 scopus 로고    scopus 로고
    • Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloiddepositing transgenic mice
    • Lebson L, Nash K, Kamath S, et al. Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloiddepositing transgenic mice. J Neurosci 2010; 30 (29): 9651-8.
    • (2010) J Neurosci , vol.30 , Issue.29 , pp. 9651-9658
    • Lebson, L.1    Nash, K.2    Kamath, S.3
  • 34
    • 59049104731 scopus 로고    scopus 로고
    • Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy
    • Hawkes CA, McLaurin J. Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy. Proc Natl Acad Sci USA 2009; 106 (4): 1261-6.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.4 , pp. 1261-1266
    • Hawkes, C.A.1    McLaurin, J.2
  • 35
    • 79961234274 scopus 로고    scopus 로고
    • Distinct and nonredundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease
    • Mildner A, Schlevogt B, Kierdorf K, et al. Distinct and nonredundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci 2011; 31 (31): 11159-71.
    • (2011) J Neurosci , vol.31 , Issue.31 , pp. 11159-11171
    • Mildner, A.1    Schlevogt, B.2    Kierdorf, K.3
  • 36
    • 84887611153 scopus 로고    scopus 로고
    • Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta
    • Michaud JP, Bellavance MA, Préfontaine P, Rivest S. Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta. Cell 2013; 5 (3): 646-53.
    • (2013) Cell , vol.5 , Issue.3 , pp. 646-653
    • Michaud, J.P.1    Bellavance, M.A.2    Préfontaine, P.3    Rivest, S.4
  • 37
    • 7344246592 scopus 로고    scopus 로고
    • Amyloid-beta induces chemokine secretion and monocyte migration across a human blood-brain barrier model
    • Fiala M, Zhang L, Gan X, et al. Amyloid-beta induces chemokine secretion and monocyte migration across a human blood-brain barrier model. Mol Med 1998; 4 (7): 480-9.
    • (1998) Mol Med , vol.4 , Issue.7 , pp. 480-489
    • Fiala, M.1    Zhang, L.2    Gan, X.3
  • 38
    • 84916880927 scopus 로고    scopus 로고
    • Decreased Expression of Cathepsin D in Monocytes is Related to the Defective Degradation of Amyloid-β in Alzheimer's Disease
    • Tian L, Zhang K, Tian ZY, et al. Decreased Expression of Cathepsin D in Monocytes is Related to the Defective Degradation of Amyloid-β in Alzheimer's Disease. J Alzheimers Dis 2014; 42 (2): 511-20.
    • (2014) J Alzheimers Dis , vol.42 , Issue.2 , pp. 511-520
    • Tian, L.1    Zhang, K.2    Tian, Z.Y.3
  • 39
    • 59649100859 scopus 로고    scopus 로고
    • Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases
    • van Gils JM, Zwaginga JJ, Hordijk PL. Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases. J Leukoc Biol 2009; 85 (2): 195-204.
    • (2009) J Leukoc Biol , vol.85 , Issue.2 , pp. 195-204
    • Van Gils, J.M.1    Zwaginga, J.J.2    Hordijk, P.L.3
  • 40
    • 64249119447 scopus 로고    scopus 로고
    • Platelet-mediated enhancement of leukocyte adhesion
    • von Hundelshausen, P., Koenen, R.R., Weber, C. Platelet-mediated enhancement of leukocyte adhesion. Microcirculation 2009; 16 (1): 84-96.
    • (2009) Microcirculation , vol.16 , Issue.1 , pp. 84-96
    • Von Hundelshausen, P.1    Koenen, R.R.2    Weber, C.3
  • 41
    • 1642471666 scopus 로고    scopus 로고
    • Cerebral microbleeds in Alzheimer's disease
    • Hanyu H, Tanaka Yu, Shimizu S, Takasaki M, Abe K. Cerebral microbleeds in Alzheimer's disease. J Neurol 2003; 250 (12): 1496-7.
    • (2003) J Neurol , vol.250 , Issue.12 , pp. 1496-1497
    • Hanyu, H.1    Yu, T.2    Shimizu, S.3    Takasaki, M.4    Abe, K.5
  • 42
    • 70350548210 scopus 로고    scopus 로고
    • Patients with Alzheimer disease with multiple microbleeds: Relation with cerebrospinal fluid biomarkers and cognition
    • Goos JD, Kester MI, Barkhof F, et al. Patients with Alzheimer disease with multiple microbleeds: relation with cerebrospinal fluid biomarkers and cognition. Stroke 2009; 40 (11): 3455-60.
    • (2009) Stroke , vol.40 , Issue.11 , pp. 3455-3460
    • Goos, J.D.1    Kester, M.I.2    Barkhof, F.3
  • 44
    • 33745212720 scopus 로고    scopus 로고
    • Microbleeds in Alzheimer disease are more related to cerebral amyloid angiopathy than cerebrovascular disease
    • Nakata-Kudo Y, Mizuno T, Yamada K, et al. Microbleeds in Alzheimer disease are more related to cerebral amyloid angiopathy than cerebrovascular disease. Dement Geriatr Cogn Disord 2006; 22 (1): 8-14
    • (2006) Dement Geriatr Cogn Disord , vol.22 , Issue.1 , pp. 8-14
    • Nakata-Kudo, Y.1    Mizuno, T.2    Yamada, K.3
  • 45
    • 45149113307 scopus 로고    scopus 로고
    • Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study
    • Pettersen JA, Sathiyamoorthy G, Gao FQ, et al. Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study. Arch Neurol 2008; 65 (6): 790-5.
    • (2008) Arch Neurol , vol.65 , Issue.6 , pp. 790-795
    • Pettersen, J.A.1    Sathiyamoorthy, G.2    Gao, F.Q.3
  • 46
    • 84891818678 scopus 로고    scopus 로고
    • Cerebrovascular pathology and amyloid plaque formation in Alzheimer's disease
    • Lee CW, Shih YH, Kuo YM. Cerebrovascular pathology and amyloid plaque formation in Alzheimer's disease. Curr Alzheimer Res 2014; 11 (1): 4-10.
    • (2014) Curr Alzheimer Res , vol.11 , Issue.1 , pp. 4-10
    • Lee, C.W.1    Shih, Y.H.2    Kuo, Y.M.3
  • 47
    • 84888211381 scopus 로고    scopus 로고
    • A physiologic biomarker for cerebral amyloid angiopathy
    • Gurol ME, Greenberg SM. A physiologic biomarker for cerebral amyloid angiopathy. http://www.ncbi.nlm.nih.gov/pubmed/24097811 Neurology 2013; 81 (19): 1650-1.
    • (2013) Neurology , vol.81 , Issue.19 , pp. 1650-1651
    • Gurol, M.E.1    Greenberg, S.M.2
  • 48
    • 0344737582 scopus 로고    scopus 로고
    • Vascular pathology in Alzheimer disease: Correlation of cerebral amyloid angiopathy and arteriosclerosis/lipohyalinosis with cognitive decline
    • Thal DR, Ghebremedhin E, Orantes M, Wiestler OD. Vascular pathology in Alzheimer disease: correlation of cerebral amyloid angiopathy and arteriosclerosis/lipohyalinosis with cognitive decline. J Neuropathol Exp Neurol 2003; 62 (12): 1287-30.
    • (2003) J Neuropathol Exp Neurol , vol.62 , Issue.12 , pp. 1287-1330
    • Thal, D.R.1    Ghebremedhin, E.2    Orantes, M.3    Wiestler, O.D.4
  • 49
    • 78649512323 scopus 로고    scopus 로고
    • Cerebral microbleeds and vascular cognitive impairment
    • Werring DJ, Gregoire SM, Cipolotti L. Cerebral microbleeds and vascular cognitive impairment, J Neurol Sci 2010; 299 (1-2): 131-5.
    • (2010) J Neurol Sci , vol.299 , Issue.1-2 , pp. 131-135
    • Werring, D.J.1    Gregoire, S.M.2    Cipolotti, L.3
  • 50
    • 84887259294 scopus 로고    scopus 로고
    • Multiple microbleeds are related to cerebral network disruptions in patients with early Alzheimer's disease
    • Utrecht Vascular Cognitive Impairment (VCI) Study Group
    • Heringa SM, Reijmer YD, Leemans A, Koek HL, Kappelle LJ, Biessels GJ; Utrecht Vascular Cognitive Impairment (VCI) Study Group. Multiple microbleeds are related to cerebral network disruptions in patients with early Alzheimer's disease. J Alzheimers Dis 2014; 38 (1): 211-21.
    • (2014) J Alzheimers Dis , vol.38 , Issue.1 , pp. 211-221
    • Heringa, S.M.1    Reijmer, Y.D.2    Leemans, A.3    Koek, H.L.4    Kappelle, L.J.5    Biessels, G.J.6
  • 51
    • 49949084427 scopus 로고    scopus 로고
    • Neurofibrillary tangles and senile plaques in Alzheimer's brains are associated with reduced capillary expression of vascular endothelial growth factor and endothelial nitric oxide synthase
    • Provias J, Jeynes B. Neurofibrillary tangles and senile plaques in Alzheimer's brains are associated with reduced capillary expression of vascular endothelial growth factor and endothelial nitric oxide synthase. Curr Neurovasc Res 2008; 5 (3): 199-205.
    • (2008) Curr Neurovasc Res , vol.5 , Issue.3 , pp. 199-205
    • Provias, J.1    Jeynes, B.2
  • 52
    • 0026750965 scopus 로고
    • Vascular dementia: Neuropathologic alterations and metabolic brain changes
    • Garcia JH, Brown GG. Vascular dementia: neuropathologic alterations and metabolic brain changes. J Neurol Sci 1992; 109 (2): 121-3.
    • (1992) J Neurol Sci , vol.109 , Issue.2 , pp. 121-123
    • Garcia, J.H.1    Brown, G.G.2
  • 53
    • 0026001083 scopus 로고
    • The pathological basis of multi-infarct dementia
    • Munoz DG. The pathological basis of multi-infarct dementia. Alzheimer Dis Assoc Disord 1991; 5 (2): 77-90.
    • (1991) Alzheimer Dis Assoc Disord , vol.5 , Issue.2 , pp. 77-90
    • Munoz, D.G.1
  • 54
    • 0030467118 scopus 로고    scopus 로고
    • Fundamental pathological lesions in vascular dementia
    • Olsson Y, Brun A, Englund E. Fundamental pathological lesions in vascular dementia. Acta Neurol Scand Suppl 1996; 168: 31-8.
    • (1996) Acta Neurol Scand Suppl , vol.168 , pp. 31-38
    • Olsson, Y.1    Brun, A.2    Englund, E.3
  • 55
    • 0034603520 scopus 로고    scopus 로고
    • Vascular risk factors for Alzheimer's disease: An epidemiologic perspective
    • Breteler MM. Vascular risk factors for Alzheimer's disease: an epidemiologic perspective. Neurobiol Aging 2000; 21 (2): 153-60.
    • (2000) Neurobiol Aging , vol.21 , Issue.2 , pp. 153-160
    • Breteler, M.M.1
  • 56
    • 84867575586 scopus 로고    scopus 로고
    • Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood-brain barrier leakage in rats in vivo
    • Ehrlich D, Humpel C. Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood-brain barrier leakage in rats in vivo. J Neurol Sci 2012; 322 (1-2): 92-5.
    • (2012) J Neurol Sci , vol.322 , Issue.1-2 , pp. 92-95
    • Ehrlich, D.1    Humpel, C.2
  • 57
    • 34147144197 scopus 로고    scopus 로고
    • Relationship of vascular risk to the progression of Alzheimer disease
    • Borroni B, Archetti S, Ferrari M, Cesana BM, Padovani A. Relationship of vascular risk to the progression of Alzheimer disease. Neurology 2007; 68 (13): 1083-1084.
    • (2007) Neurology , vol.68 , Issue.13 , pp. 1083-1084
    • Borroni, B.1    Archetti, S.2    Ferrari, M.3    Cesana, B.M.4    Padovani, A.5
  • 58
    • 84857677456 scopus 로고    scopus 로고
    • Platelets: A critical link between inflammation and microvascular dysfunction
    • Stokes KY, Granger DN. Platelets: a critical link between inflammation and microvascular dysfunction. J Physiol 2012; 590 (5): 1023-34.
    • (2012) J Physiol , vol.590 , Issue.5 , pp. 1023-1034
    • Stokes, K.Y.1    Granger, D.N.2
  • 59
    • 84922002985 scopus 로고    scopus 로고
    • A platelet protein biochip rapidly detects an Alzheimer's disease-specific phenotype
    • Veitinger M, Oehler R, Umlauf E, et al. A platelet protein biochip rapidly detects an Alzheimer's disease-specific phenotype. Acta Neuropathol. 2014; 128 (5): 665-77.
    • (2014) Acta Neuropathol , vol.128 , Issue.5 , pp. 665-677
    • Veitinger, M.1    Oehler, R.2    Umlauf, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.