Characterizing and controlling intrinsic biases of lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication origins

Genome Research

Volumn 125, Issue 5, 2015, Pages 725-735

  Foulk, Michael S ^a,b   Urban, John M ^a   Casella, Cinzia ^a,c   Gerbi, Susan A ^a  

^a BROWN UNIVERSITY   (United States)

^b MERCYHURST COLLEGE   (United States)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

EXONUCLEASE; GENOMIC DNA; GUANINE QUADRUPLEX; LAMBDA EXONUCLEASE; UNCLASSIFIED DRUG; EXO PROTEIN, BACTERIOPHAGE LAMBDA; EXODEOXYRIBONUCLEASE; NUCLEOSOME; RIBOSOME DNA; VIRAL PROTEIN;

ARTICLE; AT RICH SEQUENCE; CONTROLLED STUDY; CPG ISLAND; DNA BASE COMPOSITION; DNA REPLICATION ORIGIN; DNA STRUCTURE; GC RICH SEQUENCE; GENE SEQUENCE; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; MCF 7 CELL LINE; NASCENT STRAND SEQUENCE; NUCLEOSOME; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; CHEMISTRY; DNA SEQUENCE; GENETICS; MCF-7 CELL LINE; METABOLISM; PROCEDURES;

DNA, RIBOSOMAL; EXODEOXYRIBONUCLEASES; G-QUADRUPLEXES; GC RICH SEQUENCE; HUMANS; MCF-7 CELLS; NUCLEOSOMES; REPLICATION ORIGIN; SEQUENCE ANALYSIS, DNA; VIRAL PROTEINS;

EID: 84924634587     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.183848.114     Document Type: Article

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