Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in leukemia cells

Cell Cycle

Volumn 14, Issue 5, 2015, Pages 761-771

  Liao, Yuanhong ^a   Ling, Jianya ^b   Zhang, Guoying ^c   Liu, Fengjun ^d   Tao, Shengce ^a   Han, Zeguang ^a,e   Chen, Saijuan ^a,f   Chen, Zhu ^a,f   Le, Huangying ^a  

^a Chinese National Human Genome Center at Shanghai   (China)

^b SHANDONG UNIVERSITY   (China)

^c SHANDONG UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d THE FIRST AFFILIATED HOSPITAL OF SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^e CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

^f SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DERIVATIVE; CASPASE 9; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 25A; CORDYCEPIN; CYCLIN DEPENDENT KINASE 2; CYCLIN E; CYTOCHROME C; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN P53; UNCLASSIFIED DRUG; CASPASE; DEOXYADENOSINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL GROWTH; CHINESE MEDICINE; CONTROLLED STUDY; CORDYCEPS; CYTOSOL; CYTOTOXICITY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRION; MUSHROOM; TRADITIONAL MEDICINE; U937 CELL LINE; APOPTOSIS; BIOLOGICAL MODEL; CELL CYCLE CHECKPOINT; CHEMISTRY; DRUG EFFECTS; LEUKEMIA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; UPREGULATION;

CORDYCEPS MILITARIS;

APOPTOSIS; CASPASES; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DEOXYADENOSINES; DNA DAMAGE; HUMANS; LEUKEMIA; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84924630161     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2014.1000097     Document Type: Article

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