Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)

FEBS Letters

Volumn 585, Issue 16, 2011, Pages 2568-2574

  Dennissen, Frank J A ^a   Kholod, Natalia ^a   Hermes, Denise J H P ^a   Kemmerling, Nadja ^a   Steinbusch, Harry W M ^a   Dantuma, Nico P ^b   Van Leeuwen, Fred W ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Alzheimer's disease; UBB+1; Ubiquitin C terminal hydrolase L3; Yeast ubiquitin hydrolase 1

Indexed keywords

HYDROLYASE; MUTANT PROTEIN; MUTANT UBIQUITIN; RECOMBINANT PROTEIN; UBIQUITIN; UBIQUITIN CARBOXY TERMINAL HYDROLASE L3; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN TISSUE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEUBIQUITINATION; GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN HYDROLYSIS; PROTEIN MODIFICATION; SACCHAROMYCES CEREVISIAE; YUH1 GENE;

ANIMALS; CYSTEINE ENDOPEPTIDASES; ENDOPEPTIDASES; HEK293 CELLS; HELA CELLS; HUMANS; HYDROLYSIS; MICE; MUTANT PROTEINS; NEURODEGENERATIVE DISEASES; OXIDATION-REDUCTION; SEQUENCE DELETION; UBIQUITIN;

SACCHAROMYCES CEREVISIAE;

EID: 80051799492     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.06.037     Document Type: Article

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