Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation

Cell Reports

Volumn 10, Issue 8, 2015, Pages 1335-1348

  Zhang, Daoxiang ^a,b   Wang, Yongbin ^a   Shi, Zhimin ^a   Liu, Jingyi ^d   Sun, Pan ^a   Hou, Xiaodan ^a   Zhang, Jian ^a   Zhao, Shimin ^c   Zhou, Binhua P ^d   Mi, Jun ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; CALVASCULIN; F ACTIN; FUMARIC ACID; GLUCOSE; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 3 ALPHA; MICRORNA; MICRORNA 424; PLATELET DERIVED GROWTH FACTOR; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE DOMAIN 2; SUCCINIC ACID; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ALPHA-KETOGLUTARIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MIRN424 MICRORNA, HUMAN; NDUFA4L2 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SMALL INTERFERING RNA;

AEROBIC GLYCOLYSIS; AEROBIC METABOLISM; ARTICLE; CANCER ASSOCIATED FIBROBLAST; CELL METABOLISM; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLAST; GENE; GENE OVEREXPRESSION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; MELANOMA; NDUFA4L2 GENE; NUCLEAR REPROGRAMMING; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; TRANSCRIPTION REGULATION; TUMOR GROWTH; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL CULTURE; COLON TUMOR; CYTOLOGY; DRUG EFFECTS; GENETICS; GLYCOLYSIS; METABOLIC ENGINEERING; METABOLISM; MOUSE; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION;

ANIMALS; CELLS, CULTURED; COLONIC NEOPLASMS; DOWN-REGULATION; ELECTRON TRANSPORT COMPLEX I; FIBROBLASTS; GLUCOSE; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOCITRATE DEHYDROGENASE; KETOGLUTARIC ACIDS; METABOLIC ENGINEERING; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; OXIDATIVE PHOSPHORYLATION; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROLYL HYDROXYLASES; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84924576198     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.02.006     Document Type: Article

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