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Volumn 65, Issue 9, 2005, Pages 3772-3780

Suppression of tumor development and metastasis formation in mice lacking the S100A4(mts1) gene

Author keywords

[No Author keywords available]

Indexed keywords

CALVASCULIN; MATRIGEL; PROTEIN S 100; UNCLASSIFIED DRUG;

EID: 18144412747     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-4510     Document Type: Article
Times cited : (199)

References (52)
  • 1
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
    • Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003;3:453-8.
    • (2003) Nat Rev Cancer , vol.3 , pp. 453-458
    • Fidler, I.J.1
  • 2
    • 4444371768 scopus 로고    scopus 로고
    • S100 proteins in mouse and man: From evolution to function and pathology (including an update of the nomenclature)
    • Marenholz I, Heizmann CW, Fritz G. S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). Biochem Biophys Res Commun 2004;322:1111-22.
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 1111-1122
    • Marenholz, I.1    Heizmann, C.W.2    Fritz, G.3
  • 3
    • 0029912643 scopus 로고    scopus 로고
    • Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 gene
    • Ambartsumian NS, Grigorian MS, Larsen IF, et al. Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 gene. Oncogene 1996;13:1621-30.
    • (1996) Oncogene , vol.13 , pp. 1621-1630
    • Ambartsumian, N.S.1    Grigorian, M.S.2    Larsen, I.F.3
  • 4
    • 0029860590 scopus 로고    scopus 로고
    • Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours
    • Davies MP, Rudland PS, Robertson L, Parry EW, Jolicoeur P, Barraclough R. Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours. Oncogene 1996;13:1631-7.
    • (1996) Oncogene , vol.13 , pp. 1631-1637
    • Davies, M.P.1    Rudland, P.S.2    Robertson, L.3    Parry, E.W.4    Jolicoeur, P.5    Barraclough, R.6
  • 5
    • 0038745381 scopus 로고    scopus 로고
    • The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis
    • Xue C, Plieth D, Venkov C, Xu C, Neilson EG. The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis. Cancer Res 2003;63:3386-94.
    • (2003) Cancer Res , vol.63 , pp. 3386-3394
    • Xue, C.1    Plieth, D.2    Venkov, C.3    Xu, C.4    Neilson, E.G.5
  • 6
    • 0036144144 scopus 로고    scopus 로고
    • Protein S100A4: Too long overlooked by pathologists?
    • Mazzucchelli L. Protein S100A4: too long overlooked by pathologists? Am J Pathol 2002;160:7-13.
    • (2002) Am J Pathol , vol.160 , pp. 7-13
    • Mazzucchelli, L.1
  • 7
    • 0036008726 scopus 로고    scopus 로고
    • Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancer
    • Davies BR, O'Donnell M, Durkan GC, et al. Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancer. J Pathol 2002;196:292-9.
    • (2002) J Pathol , vol.196 , pp. 292-299
    • Davies, B.R.1    O'Donnell, M.2    Durkan, G.C.3
  • 8
    • 0036829087 scopus 로고    scopus 로고
    • Prognostic significance of calcium-binding protein S100A4 in colorectal cancer
    • Gongoll S, Peters G, Mengel M, et al. Prognostic significance of calcium-binding protein S100A4 in colorectal cancer. Gastroenterology 2002;123:1478-84.
    • (2002) Gastroenterology , vol.123 , pp. 1478-1484
    • Gongoll, S.1    Peters, G.2    Mengel, M.3
  • 9
    • 0034200863 scopus 로고    scopus 로고
    • Clinical significance of S100A4 and E-cadherin-related adhesion molecules in non-small cell lung cancer
    • Kimura K, Endo Y, Yonemura Y, et al. Clinical significance of S100A4 and E-cadherin-related adhesion molecules in non-small cell lung cancer. Int J Oncol 2000;16:1125-31.
    • (2000) Int J Oncol , vol.16 , pp. 1125-1131
    • Kimura, K.1    Endo, Y.2    Yonemura, Y.3
  • 10
    • 5644252919 scopus 로고    scopus 로고
    • Expression of S100A4 and Met: Potential predictors for metastasis and survival in early-stage breast cancer
    • Lee WY, Su WC, Lin PW, Guo HR, Chang TW, Chen HH. Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer. Oncology 2004;66:429-8.
    • (2004) Oncology , vol.66 , pp. 429-438
    • Lee, W.Y.1    Su, W.C.2    Lin, P.W.3    Guo, H.R.4    Chang, T.W.5    Chen, H.H.6
  • 11
    • 0036581101 scopus 로고    scopus 로고
    • Prognostic significance of S100A4 expression in gallbladder cancer
    • Nakamura T, Ajiki T, Murao S, et al. Prognostic significance of S100A4 expression in gallbladder cancer. Int J Oncol 2002;20:937-41.
    • (2002) Int J Oncol , vol.20 , pp. 937-941
    • Nakamura, T.1    Ajiki, T.2    Murao, S.3
  • 12
    • 0034653733 scopus 로고    scopus 로고
    • Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancer
    • Rudland PS, Platt-Higgins A, Renshaw C, et al. Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancer. Cancer Res 2000;60:1595-603.
    • (2000) Cancer Res , vol.60 , pp. 1595-1603
    • Rudland, P.S.1    Platt-Higgins, A.2    Renshaw, C.3
  • 15
    • 0029065162 scopus 로고
    • Interaction of metastasis associated Mts1 protein with nonmuscle myosin
    • Ford HL, Zain SB. Interaction of metastasis associated Mts1 protein with nonmuscle myosin. Oncogene 1995;10:1597-605.
    • (1995) Oncogene , vol.10 , pp. 1597-1605
    • Ford, H.L.1    Zain, S.B.2
  • 16
    • 0028070116 scopus 로고
    • Involvement of S100-related calcium-binding protein pEL98 (or mts1) in cell motility and tumor cell invasion
    • Takenaga K, Nakamura Y, Endo H, Sakiyama S. Involvement of S100-related calcium-binding protein pEL98 (or mts1) in cell motility and tumor cell invasion. Jpn J Cancer Res 1994;85:831-9.
    • (1994) Jpn J Cancer Res , vol.85 , pp. 831-839
    • Takenaga, K.1    Nakamura, Y.2    Endo, H.3    Sakiyama, S.4
  • 17
    • 0842265101 scopus 로고    scopus 로고
    • S100A4 regulates cell motility and invasion in an in vitro model for breast cancer metastasis
    • Jenkinson SR, Barraclough R, West CR, Rudland PS. S100A4 regulates cell motility and invasion in an in vitro model for breast cancer metastasis. Br J Cancer 2004;90:253-62.
    • (2004) Br J Cancer , vol.90 , pp. 253-262
    • Jenkinson, S.R.1    Barraclough, R.2    West, C.R.3    Rudland, P.S.4
  • 18
    • 0037085308 scopus 로고    scopus 로고
    • Liprin β1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1)
    • Kriajevska M, Fischer-Larsen M, Moertz E, et al. Liprin β1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1). J Biol Chem 2002;277:5229-35.
    • (2002) J Biol Chem , vol.277 , pp. 5229-5235
    • Kriajevska, M.1    Fischer-Larsen, M.2    Moertz, E.3
  • 19
    • 0035933723 scopus 로고    scopus 로고
    • Tumor suppressor p53 protein is a new target for the metastasis- associated Mts1/S100A4 protein: Functional consequences of their interaction
    • Grigorian M, Andresen S, Tulchinsky E, et al. Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction. J Biol Chem 2001;276:22699-708.
    • (2001) J Biol Chem , vol.276 , pp. 22699-22708
    • Grigorian, M.1    Andresen, S.2    Tulchinsky, E.3
  • 20
    • 2442696687 scopus 로고    scopus 로고
    • Cancer predisposition in mice deficient for the metastasis-associated Mts1(S100A4) gene
    • EL Naaman C, Grum-Schwensen B, Mansouri A, et al. Cancer predisposition in mice deficient for the metastasis-associated Mts1(S100A4) gene. Oncogene 2004;23:3670-80.
    • (2004) Oncogene , vol.23 , pp. 3670-3680
    • El Naaman, C.1    Grum-Schwensen, B.2    Mansouri, A.3
  • 21
    • 0037135553 scopus 로고    scopus 로고
    • Methionine aminopeptidas 2 is a new target for the metastasis-associated protein, S100A4
    • Endo H, Takenaga K, Kanno T, Satoh H, Mori S. Methionine aminopeptidas 2 is a new target for the metastasis-associated protein, S100A4. J Biol Chem 2002;277:26396-402.
    • (2002) J Biol Chem , vol.277 , pp. 26396-26402
    • Endo, H.1    Takenaga, K.2    Kanno, T.3    Satoh, H.4    Mori, S.5
  • 22
    • 0031730644 scopus 로고    scopus 로고
    • Interleukin-1α and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL
    • Andersen K, Maelandsmo GM, Hovig E, Fodstad O, Loennechen T, Winberg JO. Interleukin-1α and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL. Anticancer Res 1998;18:3299-303.
    • (1998) Anticancer Res , vol.18 , pp. 3299-3303
    • Andersen, K.1    Maelandsmo, G.M.2    Hovig, E.3    Fodstad, O.4    Loennechen, T.5    Winberg, J.O.6
  • 23
    • 0033568527 scopus 로고    scopus 로고
    • S100A4 involvement in metastasis: Deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme
    • Bjornland K, Winberg JO. Odegaard OT, et al. S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme. Cancer Res 1999;55:4702-8.
    • (1999) Cancer Res , vol.55 , pp. 4702-4708
    • Bjornland, K.1    Winberg, J.O.2    Odegaard, O.T.3
  • 24
    • 0034731327 scopus 로고    scopus 로고
    • Oligomeric forms of the metastasis-related Mts1 (S100A4) protein stimulate neuronal differentiation in cultures of rat hippocampal neurons
    • Novitskaya V, Grigorian M, Kriajevska M, et al. Oligomeric forms of the metastasis-related Mts1 (S100A4) protein stimulate neuronal differentiation in cultures of rat hippocampal neurons. J Biol Chem 2000;275:41278-86.
    • (2000) J Biol Chem , vol.275 , pp. 41278-41286
    • Novitskaya, V.1    Grigorian, M.2    Kriajevska, M.3
  • 26
    • 1242351268 scopus 로고    scopus 로고
    • Extracellular S100A4 stimulates the migration rate of astrocytic tumor cells by modifying the organization of their actin cytoskeleton
    • Belot N, Pochet R, Heizmann CW, Kiss R, Decaestecker C. Extracellular S100A4 stimulates the migration rate of astrocytic tumor cells by modifying the organization of their actin cytoskeleton. Biochim Biophys Acta 2002;1600:74-83.
    • (2002) Biochim Biophys Acta , vol.1600 , pp. 74-83
    • Belot, N.1    Pochet, R.2    Heizmann, C.W.3    Kiss, R.4    Decaestecker, C.5
  • 27
    • 17944368283 scopus 로고    scopus 로고
    • The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor
    • Ambartsumian N, Klingelhofer J, Grigorian M, et al. The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor. Oncogene 2001;20:4685-95.
    • (2001) Oncogene , vol.20 , pp. 4685-4695
    • Ambartsumian, N.1    Klingelhofer, J.2    Grigorian, M.3
  • 28
    • 3843095048 scopus 로고    scopus 로고
    • Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity
    • Schmidt-Hansen B, Ornas D, Grigorian M, et al. Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity. Oncogene 2004;23:5487-95.
    • (2004) Oncogene , vol.23 , pp. 5487-5495
    • Schmidt-Hansen, B.1    Ornas, D.2    Grigorian, M.3
  • 30
    • 2642575862 scopus 로고    scopus 로고
    • Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay
    • Schmidt-Hansen B, Klingelhofer J, Grum-Schwensen B, et al. Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay. J Biol Chem 2004;279:24498-504.
    • (2004) J Biol Chem , vol.279 , pp. 24498-24504
    • Schmidt-Hansen, B.1    Klingelhofer, J.2    Grum-Schwensen, B.3
  • 31
    • 0024697280 scopus 로고
    • Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family
    • Ebralidze A, Tulchinsky E, Grigorian M, et al. Isolation and characterisation of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family. Genes Dev 1989;3:1086-93.
    • (1989) Genes Dev , vol.3 , pp. 1086-1093
    • Ebralidze, A.1    Tulchinsky, E.2    Grigorian, M.3
  • 32
    • 84883840386 scopus 로고
    • Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines
    • Todaro GJ, Green H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 1963;17:299-313.
    • (1963) J Cell Biol , vol.17 , pp. 299-313
    • Todaro, G.J.1    Green, H.2
  • 33
    • 2542612884 scopus 로고    scopus 로고
    • Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment: A novel resource for biomarker and therapeutic target discovery
    • Celis JE, Gromov P, Cabezon T, et al. Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment: a novel resource for biomarker and therapeutic target discovery. Mol Cell Proteomics 2004;3:327-44.
    • (2004) Mol Cell Proteomics , vol.3 , pp. 327-344
    • Celis, J.E.1    Gromov, P.2    Cabezon, T.3
  • 34
    • 0037899253 scopus 로고    scopus 로고
    • Role of tissue stroma in cancer cell invasion
    • De Wever O, Mareel M. Role of tissue stroma in cancer cell invasion. J Pathol 2003;200:429-47.
    • (2003) J Pathol , vol.200 , pp. 429-447
    • De Wever, O.1    Mareel, M.2
  • 35
    • 13144273084 scopus 로고    scopus 로고
    • Sensitization of interferon-γ induced apoptosis in human osteosarcoma cells by extracellular S100A4
    • Pedersen KB, Andersen K, Fodstad Ã, Maelandsmo GM. Sensitization of interferon-γ induced apoptosis in human osteosarcoma cells by extracellular S100A4. BMC Cancer 2004;4:52.
    • (2004) BMC Cancer , vol.4 , pp. 52
    • Pedersen, K.B.1    Andersen, K.2    Fodstad, Ã.3    Maelandsmo, G.M.4
  • 36
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta LA, Kohn EC. The microenvironment of the tumour-host interface. Nature 2001;411:375-9.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 37
    • 0028808337 scopus 로고
    • Expression of Mts1, a metastasis-associated gene, increases motility but not invasion of a nonmetastatic mouse mammary adenocarcinoma cell line
    • Ford HL, Salim MM, Chakravarty R, Aluiddin V, Zain SB. Expression of Mts1, a metastasis-associated gene, increases motility but not invasion of a nonmetastatic mouse mammary adenocarcinoma cell line. Oncogene 1995;11:2067-75.
    • (1995) Oncogene , vol.11 , pp. 2067-2075
    • Ford, H.L.1    Salim, M.M.2    Chakravarty, R.3    Aluiddin, V.4    Zain, S.B.5
  • 39
    • 0028122690 scopus 로고
    • Heterogeneity of myofibroblast phenotypic features: An example of fibroblastic cell plasticity
    • Schmitt-Graff A, Desmouliere A, Gabbiani G. Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Arch 1994;425:3-24.
    • (1994) Virchows Arch , vol.425 , pp. 3-24
    • Schmitt-Graff, A.1    Desmouliere, A.2    Gabbiani, G.3
  • 41
    • 3042749576 scopus 로고    scopus 로고
    • Role of infiltrated leucocytes in tumor growth and spread
    • Lin EY, Pollard JW. Role of infiltrated leucocytes in tumor growth and spread. Br J Cancer 2004;90:2053-8.
    • (2004) Br J Cancer , vol.90 , pp. 2053-2058
    • Lin, E.Y.1    Pollard, J.W.2
  • 42
    • 0347123433 scopus 로고    scopus 로고
    • Tumor-educated macrophages promote tumor progression and metastasis
    • Pollard JW. Tumor-educated macrophages promote tumor progression and metastasis. Nat Rev Cancer 2004;4:71-8.
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 43
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression Nature. 2004;432:332-7.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 44
    • 2342640981 scopus 로고    scopus 로고
    • Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions
    • Ohuchida K, Mizumoto K, Murakami M, et al. Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions. Cancer Res 2004;64:3215-22.
    • (2004) Cancer Res , vol.64 , pp. 3215-3222
    • Ohuchida, K.1    Mizumoto, K.2    Murakami, M.3
  • 45
    • 0033215242 scopus 로고    scopus 로고
    • Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
    • Olumi AF, Grossfeld GD, Harvard SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999;59:5002-11.
    • (1999) Cancer Res , vol.59 , pp. 5002-5011
    • Olumi, A.F.1    Grossfeld, G.D.2    Harvard, S.W.3    Carroll, P.R.4    Tlsty, T.D.5    Cunha, G.R.6
  • 46
    • 0032559821 scopus 로고    scopus 로고
    • In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy
    • Masson R, Lefebvre O, Noel A, et al. In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy. J Cell Biol 1998;140:1535-41.
    • (1998) J Cell Biol , vol.140 , pp. 1535-1541
    • Masson, R.1    Lefebvre, O.2    Noel, A.3
  • 47
    • 0037069926 scopus 로고    scopus 로고
    • Plasminogen promotes sarcoma growth and suppresses the accumulation of tumor-infiltrating macrophages
    • Curino A, Mitola DJ, Aaronson H, et al. Plasminogen promotes sarcoma growth and suppresses the accumulation of tumor-infiltrating macrophages. Oncogene 2002;21:8830-42.
    • (2002) Oncogene , vol.21 , pp. 8830-8842
    • Curino, A.1    Mitola, D.J.2    Aaronson, H.3
  • 48
    • 0034667385 scopus 로고    scopus 로고
    • Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
    • Gutierrez LS, Schulman A, Brito-Robinson T, Noria F, Ploplis VA, Castellino FJ. Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1. Cancer Res 2000;60:5839-47.
    • (2000) Cancer Res , vol.60 , pp. 5839-5847
    • Gutierrez, L.S.1    Schulman, A.2    Brito-Robinson, T.3    Noria, F.4    Ploplis, V.A.5    Castellino, F.J.6
  • 49
    • 0030662107 scopus 로고    scopus 로고
    • Growth and dissemination of Lewis lung carcinoma in plasminogen-deficient mice
    • Bugge TH, Kombrinck KW, Xiao Q, et al. Growth and dissemination of Lewis lung carcinoma in plasminogen-deficient mice. Blood 1997;90:4522-31.
    • (1997) Blood , vol.90 , pp. 4522-4531
    • Bugge, T.H.1    Kombrinck, K.W.2    Xiao, Q.3
  • 50
    • 0034721666 scopus 로고    scopus 로고
    • MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
    • Coussens LM, Tinkle CL, Hanahan D, Werb Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 2000;103:481-90.
    • (2000) Cell , vol.103 , pp. 481-490
    • Coussens, L.M.1    Tinkle, C.L.2    Hanahan, D.3    Werb, Z.4
  • 51
    • 0032789885 scopus 로고    scopus 로고
    • Experimental metastasis is suppressed in MMP-9-deficient mice
    • Itoh T, Tanioka M, Matsuda H. et al. Experimental metastasis is suppressed in MMP-9-deficient mice. Clin Exp Metastasis 1999;17:177-81.
    • (1999) Clin Exp Metastasis , vol.17 , pp. 177-181
    • Itoh, T.1    Tanioka, M.2    Matsuda, H.3
  • 52
    • 0035940429 scopus 로고    scopus 로고
    • Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of MMP-9 and mobilization of vascular endothelial growth factor
    • Rodriguez-Manzaneque JC, Lane TF, Ortega MA, Hyrtes RO, Lawler J, Iruela-Arispe ML. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of MMP-9 and mobilization of vascular endothelial growth factor. Proc Natl Acad Sci USA 2001;98:12485-90.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12485-12490
    • Rodriguez-Manzaneque, J.C.1    Lane, T.F.2    Ortega, M.A.3    Hyrtes, R.O.4    Lawler, J.5    Iruela-Arispe, M.L.6


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