-
1
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
Balch, W. E., Morimoto, R. I., Dillin, A. & Kelly, J. W. Adapting proteostasis for disease intervention. Science 319, 916-919 (2008).
-
(2008)
Science
, vol.319
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
2
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron, D. & Walter, P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8, 519-529 (2007).
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
3
-
-
84897129156
-
Differential scales of protein quality control
-
Wolff, S., Weissman, J. S. & Dillin, A. Differential scales of protein quality control. Cell 157, 52-64 (2014).
-
(2014)
Cell
, vol.157
, pp. 52-64
-
-
Wolff, S.1
Weissman, J.S.2
Dillin, A.3
-
4
-
-
84906794886
-
Proteostasis impairment in protein-misfolding and -aggregation diseases
-
Hipp, M., S., Park, S. H. & Hartl, F. U. Proteostasis impairment in protein-misfolding and -aggregation diseases. Trends Cell Biol. 24, 506-514 (2014).
-
(2014)
Trends Cell Biol.
, vol.24
, pp. 506-514
-
-
Hipp, M.S.1
Park, S.H.2
Hartl, F.U.3
-
5
-
-
0029564954
-
Heat shock transcription factors: Structure and regulation
-
Wu, C. Heat shock transcription factors: structure and regulation. Annu. Rev. Cell Dev. Biol. 11, 441-469 (1995).
-
(1995)
Annu. Rev. Cell Dev. Biol.
, vol.11
, pp. 441-469
-
-
Wu, C.1
-
6
-
-
77957252262
-
The heat shock factor family and adaptation to proteotoxic stress
-
Fujimoto, M. & Nakai, A. The heat shock factor family and adaptation to proteotoxic stress. FEBS J. 277, 4112-4125 (2010).
-
(2010)
FEBS J.
, vol.277
, pp. 4112-4125
-
-
Fujimoto, M.1
Nakai, A.2
-
7
-
-
0032031725
-
Molecular chaperones as HSF1-specific transcriptional repressors
-
Shi, Y., Mosser, D. D. & Morimoto, R. I. Molecular chaperones as HSF1-specific transcriptional repressors. Genes Dev. 12, 654-666 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 654-666
-
-
Shi, Y.1
Mosser, D.D.2
Morimoto, R.I.3
-
8
-
-
0032555685
-
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1
-
Zou, J., Guo, Y., Guettouche, T., Smith, D. F. & Voellmy, R. Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1. Cell 94, 471-480 (1998).
-
(1998)
Cell
, vol.94
, pp. 471-480
-
-
Zou, J.1
Guo, Y.2
Guettouche, T.3
Smith, D.F.4
Voellmy, R.5
-
9
-
-
0032535245
-
Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
-
Morimoto, R. I. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev. 12, 3788-3796 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 3788-3796
-
-
Morimoto, R.I.1
-
10
-
-
77954955686
-
Heat shock factors: Integrators of cell stress, development and lifespan
-
Akerfelt, M., Morimoto, R. I. & Sistonen, L. Heat shock factors: integrators of cell stress, development and lifespan. Nat. Rev. Mol. Cell Biol. 11, 545-555 (2010).
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 545-555
-
-
Akerfelt, M.1
Morimoto, R.I.2
Sistonen, L.3
-
11
-
-
84861531483
-
Overcoming the nucleosome barrier during transcript elongation
-
Petesch, S. J. & Lis, J. T. Overcoming the nucleosome barrier during transcript elongation. Trends Genet. 28, 285-294 (2012).
-
(2012)
Trends Genet.
, vol.28
, pp. 285-294
-
-
Petesch, S.J.1
Lis, J.T.2
-
12
-
-
77951622443
-
Mitochondrial autophagy protects against heat shock-induced apoptosis through reducing cytosolic cytochrome c release and downstream caspase-3 activation
-
Yang, Y., Xing, D., Zhou, F. & Chen, Q. Mitochondrial autophagy protects against heat shock-induced apoptosis through reducing cytosolic cytochrome c release and downstream caspase-3 activation. Biochem. Biophys. Res. Commun. 395, 190-195 (2010).
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.395
, pp. 190-195
-
-
Yang, Y.1
Xing, D.2
Zhou, F.3
Chen, Q.4
-
13
-
-
79952328398
-
Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease
-
Bender, T., Lewrens, I., Franken, S., Baitzel, C. & Voos, W. Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease. Mol. Biol. Cell. 22, 541-554 (2011).
-
(2011)
Mol. Biol. Cell.
, vol.22
, pp. 541-554
-
-
Bender, T.1
Lewrens, I.2
Franken, S.3
Baitzel, C.4
Voos, W.5
-
14
-
-
84866665390
-
Mitochondria and cancer
-
Wallace, D. C. Mitochondria and cancer. Nat. Rev. Cancer 12, 685-698 (2012).
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 685-698
-
-
Wallace, D.C.1
-
15
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer, G., Galluzzi, L. & Brenner, C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87, 99-163 (2007).
-
(2007)
Physiol. Rev.
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
16
-
-
78649728763
-
The mitochondrial UPR - protecting organelle protein homeostasis
-
Haynes, C. M. & Ron, D. The mitochondrial UPR - protecting organelle protein homeostasis. J. Cell Sci. 123, 3849-3855 (2010).
-
(2010)
J. Cell Sci.
, vol.123
, pp. 3849-3855
-
-
Haynes, C.M.1
Ron, D.2
-
17
-
-
84879602902
-
Evaluating and responding to mitochondrial dysfunction: The mitochondrial unfolded-protein response and beyond
-
Haynes, C. M., Fiorese, C. J. & Lin, Y. F. Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond. Trends Cell Biol. 23, 311-318 (2013).
-
(2013)
Trends Cell Biol.
, vol.23
, pp. 311-318
-
-
Haynes, C.M.1
Fiorese, C.J.2
Lin, Y.F.3
-
18
-
-
0037009521
-
A mitochondrial specific stress response in mammalian cells
-
Zhao, Q. et al. A mitochondrial specific stress response in mammalian cells. EMBO J. 21, 4411-4419 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 4411-4419
-
-
Zhao, Q.1
-
19
-
-
4944234936
-
Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones
-
Yoneda, T. et al. Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones. J. Cell Sci. 117, 4055-4066 (2004).
-
(2004)
J. Cell Sci.
, vol.117
, pp. 4055-4066
-
-
Yoneda, T.1
-
20
-
-
84864744900
-
Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation
-
Nargund, A. M., Pellegrino, M. W., Fiorese, C. J., Baker, B. M. & Haynes, C. M. Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation. Science 337, 587-590 (2012).
-
(2012)
Science
, vol.337
, pp. 587-590
-
-
Nargund, A.M.1
Pellegrino, M.W.2
Fiorese, C.J.3
Baker, B.M.4
Haynes, C.M.5
-
22
-
-
0024380865
-
Identification, characterization, and purification of two mammalian stress proteins present in mitochondria, grp 75, a member of the hsp 70 family and hsp 58, a homolog of the bacterial groEL protein
-
Mizzen, L. A., Chang, C., Garrels, J. I. & Welch, W. J. Identification, characterization, and purification of two mammalian stress proteins present in mitochondria, grp 75, a member of the hsp 70 family and hsp 58, a homolog of the bacterial groEL protein. J. Biol. Chem. 64, 20664-20675 (1989).
-
(1989)
J. Biol. Chem.
, vol.64
, pp. 20664-20675
-
-
Mizzen, L.A.1
Chang, C.2
Garrels, J.I.3
Welch, W.J.4
-
23
-
-
77953811054
-
The human mitochondrial replication fork in health and disease
-
Wanrooij, S. & Falkenberg, M. The human mitochondrial replication fork in health and disease. Biochim. Biophys. Acta 1797, 1378-1388 (2010).
-
(2010)
Biochim. Biophys. Acta
, vol.1797
, pp. 1378-1388
-
-
Wanrooij, S.1
Falkenberg, M.2
-
24
-
-
84868088016
-
RPA assists HSF1 access to nucleosomal DNA by recruiting histone chaperone FACT
-
Fujimoto, M. et al. RPA assists HSF1 access to nucleosomal DNA by recruiting histone chaperone FACT. Mol. Cell 48, 182-194 (2012).
-
(2012)
Mol. Cell
, vol.48
, pp. 182-194
-
-
Fujimoto, M.1
-
25
-
-
0026621935
-
Trimerization of the heat shock transcription factor by a triple-stranded alpha-helical coiled-coil
-
Peteranderl, R. & Nelson, H. C. Trimerization of the heat shock transcription factor by a triple-stranded alpha-helical coiled-coil. Biochemistry 31, 12272-12276 (1992).
-
(1992)
Biochemistry
, vol.31
, pp. 12272-12276
-
-
Peteranderl, R.1
Nelson, H.C.2
-
26
-
-
0031930319
-
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
-
Larsson, N. G. et al. Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nature Genet 18, 231-236 (1998).
-
(1998)
Nature Genet
, vol.18
, pp. 231-236
-
-
Larsson, N.G.1
-
27
-
-
33845629364
-
Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells
-
Pohjoismäki, J. L. et al. Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells. Nucleic Acids Res. 34, 5815-5828 (2006).
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 5815-5828
-
-
Pohjoismäki, J.L.1
-
28
-
-
0027461364
-
Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress
-
Sarge, K. D., Murphy, S. P. & Morimoto, R. I. Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress. Mol. Cell. Biol. 13, 1392-1407 (1993).
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1392-1407
-
-
Sarge, K.D.1
Murphy, S.P.2
Morimoto, R.I.3
-
29
-
-
84893317772
-
Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication
-
Rajala, N., Gerhold, J. M., Martinsson, P., Klymov, A. & Spelbrink, J. N. Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication. Nucleic Acids Res 42, 952-967 (2014).
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 952-967
-
-
Rajala, N.1
Gerhold, J.M.2
Martinsson, P.3
Klymov, A.4
Spelbrink, J.N.5
-
30
-
-
0022379715
-
Morphological study of the mammalian stress response: Characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment
-
Welch, W. J. & Suhan, J. P. Morphological study of the mammalian stress response: characterization of changes in cytoplasmic organelles, cytoskeleton, and nucleoli, and appearance of intranuclear actin filaments in rat fibroblasts after heat-shock treatment. J. Cell Biol. 101, 1198-1211 (1985).
-
(1985)
J. Cell Biol.
, vol.101
, pp. 1198-1211
-
-
Welch, W.J.1
Suhan, J.P.2
-
31
-
-
0025124856
-
Structural and functional studies of the rat mitochondrial single strand DNA binding protein P16
-
Hoke, G. D., Pavco, P. A., Ledwith, B. J. & Van Tuyle, G. C. Structural and functional studies of the rat mitochondrial single strand DNA binding protein P16. Arch. Biochem. Biophys. 282, 116-124 (1990).
-
(1990)
Arch. Biochem. Biophys.
, vol.282
, pp. 116-124
-
-
Hoke, G.D.1
Pavco, P.A.2
Ledwith, B.J.3
Van Tuyle, G.C.4
-
32
-
-
0027308839
-
Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB)
-
Tiranti, V., Rocchi, M., DiDonato, S. & Zeviani, M. Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB). Gene 126, 219-225 (1993).
-
(1993)
Gene
, vol.126
, pp. 219-225
-
-
Tiranti, V.1
Rocchi, M.2
DiDonato, S.3
Zeviani, M.4
-
33
-
-
84890115517
-
Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription
-
Ryan, S. D. et al. Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription. Cell 155, 1351-1364 (2013).
-
(2013)
Cell
, vol.155
, pp. 1351-1364
-
-
Ryan, S.D.1
-
34
-
-
84862675016
-
p53 opens the mitochondrial permeability transition pore to trigger necrosis
-
Vaseva, A. V. et al. p53 opens the mitochondrial permeability transition pore to trigger necrosis. Cell 149, 1536-1548 (2012).
-
(2012)
Cell
, vol.149
, pp. 1536-1548
-
-
Vaseva, A.V.1
-
36
-
-
0031467707
-
HSF1 granules: A novel stress-induced nuclear compartment of human cells
-
Cotto, J., Fox, S. & Morimoto, R. HSF1 granules: a novel stress-induced nuclear compartment of human cells. J. Cell Sci. 110, 2925-2934 (1997).
-
(1997)
J. Cell Sci.
, vol.110
, pp. 2925-2934
-
-
Cotto, J.1
Fox, S.2
Morimoto, R.3
-
37
-
-
84905227469
-
Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition
-
Maharjan, S., Oku, M., Tsuda, M., Hoseki, J. & Sakai, Y. Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition. Sci. Rep 4, 5896 (2014).
-
(2014)
Sci. Rep
, vol.4
, pp. 5896
-
-
Maharjan, S.1
Oku, M.2
Tsuda, M.3
Hoseki, J.4
Sakai, Y.5
-
38
-
-
77951920370
-
The cardiac mitochondrion: Nexus of stress
-
Baines, C. P. The cardiac mitochondrion: nexus of stress. Annu. Rev. Physiol. 72, 61-80 (2010).
-
(2010)
Annu. Rev. Physiol.
, vol.72
, pp. 61-80
-
-
Baines, C.P.1
-
39
-
-
34247895697
-
Voltage-dependent anion channels are dispensable for mitochondrialdependent cell death
-
Baines, C. P., Kaiser, R. A., Sheiko, T., Craigen, W. J. & Molkentin, J. D. Voltage-dependent anion channels are dispensable for mitochondrialdependent cell death. Nat. Cell Biol. 9, 550-555 (2007).
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 550-555
-
-
Baines, C.P.1
Kaiser, R.A.2
Sheiko, T.3
Craigen, W.J.4
Molkentin, J.D.5
-
40
-
-
49149087268
-
Disruption of the hexokinase-VDAC complex for tumor therapy
-
Galluzzi, L., Kepp, O., Tajeddine, N. & Kroemer, G. Disruption of the hexokinase-VDAC complex for tumor therapy. Oncogene 27, 4633-4635 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 4633-4635
-
-
Galluzzi, L.1
Kepp, O.2
Tajeddine, N.3
Kroemer, G.4
-
41
-
-
71749121777
-
Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis
-
Tomasello, F. et al. Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis. Cell Res. 19, 1363-1376 (2009).
-
(2009)
Cell Res.
, vol.19
, pp. 1363-1376
-
-
Tomasello, F.1
-
42
-
-
84897109705
-
Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway
-
Wang, W. J. et al. Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat. Chem. Biol. 10, 133-140 (2014).
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 133-140
-
-
Wang, W.J.1
-
43
-
-
0030961451
-
Tetramerization and single-stranded DNA binding properties of native and mutated forms of murine mitochondrial single-stranded DNA-binding proteins
-
Li, K. & Williams, R. S. Tetramerization and single-stranded DNA binding properties of native and mutated forms of murine mitochondrial single-stranded DNA-binding proteins. J. Biol. Chem. 272, 8686-8694 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8686-8694
-
-
Li, K.1
Williams, R.S.2
-
44
-
-
0038623298
-
Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation
-
Corey, L. L., Weirich, C. S., Benjamin, I. J. & Kingston, R. E. Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. Genes Dev. 17, 1392-1401 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 1392-1401
-
-
Corey, L.L.1
Weirich, C.S.2
Benjamin, I.J.3
Kingston, R.E.4
-
45
-
-
84920000703
-
ATF1 modulates the heat shock response by regulating the stress-inducible HSF1-transcription complex
-
Takii, R. et al. ATF1 modulates the heat shock response by regulating the stress-inducible HSF1-transcription complex. Mol. Cell. Biol. 35, 11-25 (2015).
-
(2015)
Mol. Cell. Biol.
, vol.35
, pp. 11-25
-
-
Takii, R.1
-
46
-
-
84864585171
-
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers
-
Mendillo, M. L. et al. HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers. Cell 150, 549-562 (2012).
-
(2012)
Cell
, vol.150
, pp. 549-562
-
-
Mendillo, M.L.1
-
47
-
-
84883321205
-
Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells
-
Vihervaara, A. et al. Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells. Proc. Natl Acad. Sci. USA 110, E3388-E3397 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. E3388-E3397
-
-
Vihervaara, A.1
-
48
-
-
0035799352
-
Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation
-
Lin, K. M. et al. Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation. Circulation 103, 1787-1792 (2001).
-
(2001)
Circulation
, vol.103
, pp. 1787-1792
-
-
Lin, K.M.1
-
49
-
-
0042330503
-
Hsp10 and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells
-
Shan, Y. X. et al. Hsp10 and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells. J. Mol. Cell. Cardiol. 35, 1135-1143 (2003).
-
(2003)
J. Mol. Cell. Cardiol.
, vol.35
, pp. 1135-1143
-
-
Shan, Y.X.1
-
50
-
-
78549293327
-
Heat shock protein 60 regulation of the mitochondrial permeability transition pore in tumor cells
-
Ghosh, J. C., Siegelin, M. D., Dohi, T. & Altieri, D. C. Heat shock protein 60 regulation of the mitochondrial permeability transition pore in tumor cells. Cancer Res. 70, 8988-8993 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 8988-8993
-
-
Ghosh, J.C.1
Siegelin, M.D.2
Dohi, T.3
Altieri, D.C.4
-
51
-
-
34250561475
-
A new puffing pattern induced by heat shock and DNP in Drosophila
-
Ritossa, F. A new puffing pattern induced by heat shock and DNP in Drosophila . Experientia 18, 571-573 (1962).
-
(1962)
Experientia
, vol.18
, pp. 571-573
-
-
Ritossa, F.1
-
52
-
-
0018382014
-
The induction of gene activity in drosophilia by heat shock
-
Ashburner, M. & Bonner, J. J. The induction of gene activity in drosophilia by heat shock. Cell 17, 241-254 (1979).
-
(1979)
Cell
, vol.17
, pp. 241-254
-
-
Ashburner, M.1
Bonner, J.J.2
-
53
-
-
0022555843
-
The heat-shock response
-
Lindquist, S. The heat-shock response. Annu. Rev. Biochem. 55, 1151-1191 (1986).
-
(1986)
Annu. Rev. Biochem.
, vol.55
, pp. 1151-1191
-
-
Lindquist, S.1
-
54
-
-
84893853030
-
Molecular chaperones and proteostasis regulation during redox imbalance
-
Niforou, K., Cheimonidou, C. & Trougakos, I. P. Molecular chaperones and proteostasis regulation during redox imbalance. Redox Biol 2, 323-332 (2014).
-
(2014)
Redox Biol
, vol.2
, pp. 323-332
-
-
Niforou, K.1
Cheimonidou, C.2
Trougakos, I.P.3
-
55
-
-
0037176860
-
Redox-dependent regulation of the conformation and function of human heat shock factor 1
-
Manalo, D. J., Lin, Z. & Liu, A. Y. Redox-dependent regulation of the conformation and function of human heat shock factor 1. Biochemistry 41, 2580-2588 (2002).
-
(2002)
Biochemistry
, vol.41
, pp. 2580-2588
-
-
Manalo, D.J.1
Lin, Z.2
Liu, A.Y.3
-
56
-
-
0037442768
-
Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress
-
Ahn, S. G. & Thiele, D. J. Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress. Genes Dev. 17, 516-528 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 516-528
-
-
Ahn, S.G.1
Thiele, D.J.2
-
57
-
-
42449139730
-
Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication
-
Wiedmer, A. et al. Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication. J. Virol. 82, 4647-4655 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 4647-4655
-
-
Wiedmer, A.1
-
58
-
-
84867722747
-
Physiological roles of the permeability transition pore
-
Brenner, C. & Moulin, M. Physiological roles of the permeability transition pore. Circ. Res. 111, 1237-1247 (2012).
-
(2012)
Circ. Res.
, vol.111
, pp. 1237-1247
-
-
Brenner, C.1
Moulin, M.2
-
59
-
-
0035487007
-
The mitochondrial permeability transition initiates autophagy in rat hepatocytes
-
Elmore, S. P., Qian, T., Grissom, S. F. & Lemasters, J. J. The mitochondrial permeability transition initiates autophagy in rat hepatocytes. FASEB J. 15, 2286-2297 (2001).
-
(2001)
FASEB J.
, vol.15
, pp. 2286-2297
-
-
Elmore, S.P.1
Qian, T.2
Grissom, S.F.3
Lemasters, J.J.4
-
60
-
-
84903954689
-
A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation
-
Sutendra, G. et al. A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation. Cell 158, 84-97 (2014).
-
(2014)
Cell
, vol.158
, pp. 84-97
-
-
Sutendra, G.1
-
61
-
-
0036790590
-
Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage
-
Yan, L. J. et al. Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. EMBO J. 21, 5164-5172 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 5164-5172
-
-
Yan, L.J.1
-
62
-
-
33646199490
-
Maintenance of olfactory neurogenesis requires HSF1, a major heat shock transcription factor in mice
-
Takaki, E. et al. Maintenance of olfactory neurogenesis requires HSF1, a major heat shock transcription factor in mice. J. Biol. Chem. 281, 4931-4937 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 4931-4937
-
-
Takaki, E.1
-
63
-
-
84878138385
-
Mitonuclear protein imbalance as a conserved longevity mechanism
-
Houtkooper, R. H. et al. Mitonuclear protein imbalance as a conserved longevity mechanism. Nature 497, 451-457 (2013).
-
(2013)
Nature
, vol.497
, pp. 451-457
-
-
Houtkooper, R.H.1
-
64
-
-
84886786722
-
Muscle mitohormesis promotes longevity via systemic repression of insulin signaling
-
Owusu-Ansah, E., Song, W. & Perrimon, N. Muscle mitohormesis promotes longevity via systemic repression of insulin signaling. Cell 155, 699-712 (2013).
-
(2013)
Cell
, vol.155
, pp. 699-712
-
-
Owusu-Ansah, E.1
Song, W.2
Perrimon, N.3
-
65
-
-
0038701745
-
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
-
Hsu, A. L., Murphy, C. T. & Kenyon, C. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300, 1142-1145 (2003).
-
(2003)
Science
, vol.300
, pp. 1142-1145
-
-
Hsu, A.L.1
Murphy, C.T.2
Kenyon, C.3
-
66
-
-
0742323000
-
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones
-
Morley, J. F. & Morimoto, R. I. Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. Mol. Biol. Cell 15, 657-664 (2004).
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 657-664
-
-
Morley, J.F.1
Morimoto, R.I.2
-
67
-
-
77958449033
-
Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT
-
Hayashida, N. et al. Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT. EMBO J. 29, 3459-3469 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 3459-3469
-
-
Hayashida, N.1
-
68
-
-
80053359794
-
Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation
-
Shinkawa, T. et al. Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation. Mol. Biol. Cell 22, 3571-3583 (2011).
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 3571-3583
-
-
Shinkawa, T.1
-
69
-
-
0037184954
-
Early mitochondrial activation and cytochrome c up-regulation during apoptosis
-
Chandra, D., Liu, J. W. & Tang, D. G. Early mitochondrial activation and cytochrome c up-regulation during apoptosis. J. Biol. Chem. 277, 50842-50854 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 50842-50854
-
-
Chandra, D.1
Liu, J.W.2
Tang, D.G.3
-
70
-
-
79960038600
-
Labeling mitochondria with TMRM or TMRE
-
Chazotte, B. Labeling mitochondria with TMRM or TMRE. Cold Spring Harb. Protoc 2011, 895-897 (2011).
-
(2011)
Cold Spring Harb. Protoc
, vol.2011
, pp. 895-897
-
-
Chazotte, B.1
|