Redox-dependent regulation of the conformation and function of human heat shock factor 1

Biochemistry

Volumn 41, Issue 8, 2002, Pages 2580-2588

  Manalo, Dominador J ^a,b   Lin, Zheng ^a   Liu, Alice Y C ^a  

^a RUTGERS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN HEAT SHOCKS;

AMINO ACIDS; BIOASSAY; CELLS; CONFORMATIONS; IMMUNOLOGY; MONOMERS; PROTEINS; SULFUR COMPOUNDS;

BIOCHEMISTRY;

AMINO ACID; CYSTEINE; DIAMIDE; DISULFIDE; DITHIOTHREITOL; HEAT SHOCK PROTEIN; MONOMER; SERINE; THIOL; THIOL DERIVATIVE; TRANSCRIPTION FACTOR;

ARTICLE; CONFORMATIONAL TRANSITION; CROSS LINKING; DNA BINDING; DOSE RESPONSE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MAMMAL CELL; MUTATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN MODIFICATION; WESTERN BLOTTING;

BASE SEQUENCE; CYSTEINE; DISULFIDES; DNA PRIMERS; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HELA CELLS; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PROTEIN CONFORMATION; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 0037176860     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0159682     Document Type: Article

References (43)

1. Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
2. Heat shock transcription factors: Structure and regulation
3. Transduction of the stress signal and mechanisms of transcriptional regulation of heat shock/stress protein gene expression in higher eukaryotes
4. Regulation of Drosophila heat shock factor trimerization: Global sequence requirements and independence of nuclear localization
5. Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1
6. Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress
7. Multiple layers of regulation of human heat shock transcription factor 1
8. Activation of the DNA-binding ability of human heat shock transcription factor 1 may involve the transition from an intramolecular to an intermolecular triple-stranded coiled-coil structure
9. Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation
10. Regulation of heat shock factor trimer formation: Role of a conserved leucine zipper
11. Intramolecular repression of mouse heat shock factor 1
12. Modulation of human heat shock factor trimerization by the linker domain
13. The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression
14. Heat shock gene regulation by nascent polypeptides and denatured proteins: HSP 70 as a potential autoregulatory factor
15. Negative regulation of the heat shock transcriptional response by HSBPI
16. Induction of human heat shock factor is reprogrammed in a Drosophila cell environment
17. Attenuation of the heat shock response in HeLa cells is mediated by the release of bound heat shock transcription factor and is modulated by changes in growth and in heat shock temperatures
18. In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation
19. Thiol reducing reagents inhibit the heat shock response
20. Resolution, detection, and characerization of redox conformers of human HSF1
21. Molecular cloning and expression of a human heat shock factor, HSF1
22. Agedependent decrease in the heat-inducible DNA-sequence specific activity in human diploid fibroblasts
23. Formation of disulfides with diamide
24. RsrA, an anti-sigma factor regulated by redox change
25. Isolation of a cDNA for HSF1: Evidence for two heat shock factor genes in humans
26. Formation of disulphide bonds
27. Redox control of enzyme activities by thiol/disulfide exchange
28. Bridge over troubled waters: Sensing stress by disulfide bond formation
29. Experimental studies of protein folding and unfolding
30. Stability studies on BPTI
31. Substantial increase of protein stability by multiple disulphide bonds
32. Activation of OxyR transcription factor by reversible disulfide bond formation
33. Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide status
34. Oxidative modifications in nitrosative stress
35. (S)NO signals: Translocation, regulation, and a consensus motif
36. Reaction between S-nitrosothiols and thiols: Generation of nitroxyl (HNO) and subsequent chemistry
37. Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability
38. Characterization of a novel chicken heat shock transcription factor, HSF3, suggests a new regulatory pathway
39. Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation
40. A conserved heptapeptide restrains the activity of the yeast heat shock transcription factor
41. Attenuated heat shock transcriptional response in aging: Molecular mechanisms and implications in the biology of aging
42. Protein oxidation in aging, disease, and oxidative stress