HIV-1 single-stranded RNA induces CXCL13 secretion in human monocytes via TLR7 activation and plasmacytoid dendritic cell-derived type i IFN

Journal of Immunology

Volumn 194, Issue 6, 2015, Pages 2769-2775

  Cohen, Kristen W ^a,b   Dugast, Anne Sophie ^c   Alter, Galit ^c   McElrath, M Juliana ^d   Stamatatos, Leonidas ^a,b  

^a SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; CXCL13 CHEMOKINE; INTERFERON; INTERFERON STIMULATED GENE FACTOR 3 ALPHA; MESSENGER RNA; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; ALPHA INTERFERON; ANTIRETROVIRUS AGENT; CXCL13 PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; RESIQUIMOD; VIRUS RNA;

ARTICLE; CD4 LYMPHOCYTE COUNT; CELL POPULATION; CHEMOTAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMORAL IMMUNITY; IMMUNE DYSREGULATION; IN VITRO STUDY; MONOCYTE; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE SUBPOPULATION; UPREGULATION; VIREMIA; VIRION; VIRUS LOAD; AGONISTS; BLOOD; CELL CULTURE; COHORT ANALYSIS; DENDRITIC CELL; DRUG EFFECTS; FLOW CYTOMETRY; GENE EXPRESSION; GENETICS; HIV INFECTIONS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION (PROCESS); VIROLOGY;

ANTI-RETROVIRAL AGENTS; CELLS, CULTURED; CHEMOKINE CXCL13; COHORT STUDIES; DENDRITIC CELLS; FLOW CYTOMETRY; GENE EXPRESSION; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; IMIDAZOLES; INTERFERON-ALPHA; LEUKOCYTES, MONONUCLEAR; MONOCYTES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; TOLL-LIKE RECEPTOR 7; VIREMIA;

EID: 84924559908     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400952     Document Type: Article

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