메뉴 건너뛰기




Volumn 63, Issue 9, 2015, Pages 2479-2489

Ergostatrien-3β-ol from antrodia camphorata inhibits diabetes and hyperlipidemia in high-fat-diet treated mice via regulation of hepatic related genes, glucose transporter 4, and AMP-activated protein kinase phosphorylation

Author keywords

AMP activated protein kinase phosphorylation; Antrodia camphorata; diabetes; glucose transporter 4; hypercholesterolemia; hyperlipidemia

Indexed keywords

BIOSYNTHESIS; BLOOD; CHOLESTEROL; CYTOLOGY; ENZYMES; FATTY ACIDS; GLUCOSE; INSULIN; LIPOPROTEINS; MEDICAL PROBLEMS; MUSCLE; PHOSPHORYLATION;

EID: 84924559848     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b00073     Document Type: Article
Times cited : (53)

References (42)
  • 1
    • 0023951171 scopus 로고
    • Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes
    • ORahilly, S.; Turner, R. C.; Matthews, D. R. Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes N. Engl. J. Med. 1988, 318, 1225-1230
    • (1988) N. Engl. J. Med. , vol.318 , pp. 1225-1230
    • Orahilly, S.1    Turner, R.C.2    Matthews, D.R.3
  • 3
    • 79952231175 scopus 로고    scopus 로고
    • Review of pharmacological effects of Antrodia camphorata and its bioactive compounds
    • Geethangili, M.; Tzeng, Y. M. Review of pharmacological effects of Antrodia camphorata and its bioactive compounds Evidence-Based Compl. Altern. Med. 2011, 2011, No. 212641
    • (2011) Evidence-Based Compl. Altern. Med. , vol.2011 , pp. 212641
    • Geethangili, M.1    Tzeng, Y.M.2
  • 4
    • 70349269114 scopus 로고    scopus 로고
    • Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells
    • Yeh, C. T.; Rao, Y. K.; Yao, C. J.; Yeh, C. F.; Li, C. H.; Chuang, S. E.; Luong, J. H.; Lai, G. M.; Tzeng, Y. M. Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells Cancer Lett. 2009, 285, 73-79
    • (2009) Cancer Lett. , vol.285 , pp. 73-79
    • Yeh, C.T.1    Rao, Y.K.2    Yao, C.J.3    Yeh, C.F.4    Li, C.H.5    Chuang, S.E.6    Luong, J.H.7    Lai, G.M.8    Tzeng, Y.M.9
  • 5
    • 77953639975 scopus 로고    scopus 로고
    • Analgesic effects and the mechanisms of anti-inflammation of ergostatrien-3beta-ol from Antrodia camphorata submerged whole broth in mice
    • Huang, G. J.; Huang, S. S.; Lin, S. S.; Shao, Y. Y.; Chen, C. C.; Hou, W. C. Analgesic effects and the mechanisms of anti-inflammation of ergostatrien-3beta-ol from Antrodia camphorata submerged whole broth in mice J. Agric. Food Chem. 2010, 58, 7445-7452
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 7445-7452
    • Huang, G.J.1    Huang, S.S.2    Lin, S.S.3    Shao, Y.Y.4    Chen, C.C.5    Hou, W.C.6
  • 8
    • 33947596679 scopus 로고    scopus 로고
    • The GLUT4 glucose transporter
    • Huang, S.; Czech, M. P. The GLUT4 glucose transporter Cell Metab. 2007, 5, 237-252
    • (2007) Cell Metab. , vol.5 , pp. 237-252
    • Huang, S.1    Czech, M.P.2
  • 10
    • 0035787305 scopus 로고    scopus 로고
    • Intracellular organization of insulin signaling and GLUT4 translocation
    • Watson, R. T.; Pessin, J. E. Intracellular organization of insulin signaling and GLUT4 translocation Recent Prog. Horm. Res. 2001, 56, 175-193
    • (2001) Recent Prog. Horm. Res. , vol.56 , pp. 175-193
    • Watson, R.T.1    Pessin, J.E.2
  • 13
    • 2542491213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma in diabetes and metabolism. PPAR gamma, glucose homeostasis
    • Review.
    • Rangwala, S. M.; Lazar, M. A. Peroxisome proliferator-activated receptor gamma in diabetes and metabolism. PPAR gamma, glucose homeostasis Trends Pharmacol. Sci. 2004, 25, 331-336 Review.
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 331-336
    • Rangwala, S.M.1    Lazar, M.A.2
  • 14
    • 77649189367 scopus 로고    scopus 로고
    • Rosiglitazone increases cell surface GLUT4 levels in 3T3-L1 adipocytes through an enhacement of endosomal recycling
    • Martinez, L.; Berenguer, M.; Bruce, M. C.; Le Marchand-Brustel, Y.; Govers, R. Rosiglitazone increases cell surface GLUT4 levels in 3T3-L1 adipocytes through an enhacement of endosomal recycling Biochem. Pharmacol. 2010, 79, 1300-1309
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 1300-1309
    • Martinez, L.1    Berenguer, M.2    Bruce, M.C.3    Le Marchand-Brustel, Y.4    Govers, R.5
  • 15
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten, S.; Desvergne, B.; Wahli, W. Roles of PPARs in health and disease Nature 2000, 405, 421-424
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 16
    • 0028273352 scopus 로고
    • Comparative efficacy and safety of micronised fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia
    • Farnier, M.; Bonnefous, F.; Debbas, N.; Irvine, A. Comparative efficacy and safety of micronised fenofibrate and simvastatin in patients with primary type IIa or IIb hyperlipidemia Arch. Int. Med. 1994, 154, 441-449
    • (1994) Arch. Int. Med. , vol.154 , pp. 441-449
    • Farnier, M.1    Bonnefous, F.2    Debbas, N.3    Irvine, A.4
  • 17
    • 33646192257 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-α - Selective ligand reduces adiposity, improves insulin sensitivity, and inhibits atherosclerosis in LDL receptor-deficient mice
    • Srivastava, R. A. K.; Jahagirdar, R.; Azhar, S.; Sharma, S.; Bisgaier, C. L. Peroxisome proliferator-activated receptor-α - selective ligand reduces adiposity, improves insulin sensitivity, and inhibits atherosclerosis in LDL receptor-deficient mice Mol. Cell. Biochem. 2006, 285, 35-50
    • (2006) Mol. Cell. Biochem. , vol.285 , pp. 35-50
    • Srivastava, R.A.K.1    Jahagirdar, R.2    Azhar, S.3    Sharma, S.4    Bisgaier, C.L.5
  • 18
    • 3543009434 scopus 로고    scopus 로고
    • The high-fat diet mouse: A model for studying mechanisms and type 2 diabetes
    • Winzell, M. S.; Ahrèn, B. The high-fat diet mouse: a model for studying mechanisms and type 2 diabetes Diabetes 2004, 53 (Suppl. 3) S215-219
    • (2004) Diabetes , vol.53 , Issue.SUPPL.. 3 , pp. 215-219
    • Winzell, M.S.1    Ahrèn, B.2
  • 19
    • 1842584230 scopus 로고    scopus 로고
    • Fat, carbohydrate and calories in the development of diabetes and obesity in the C57BL/6J mouse
    • Petro, A. E.; Cotter, J.; Cooper, D. A.; Peters, J. C.; Surwit, S. J.; Surwit, R. S. Fat, carbohydrate and calories in the development of diabetes and obesity in the C57BL/6J mouse Metabolism 2004, 53, 454-457
    • (2004) Metabolism , vol.53 , pp. 454-457
    • Petro, A.E.1    Cotter, J.2    Cooper, D.A.3    Peters, J.C.4    Surwit, S.J.5    Surwit, R.S.6
  • 21
    • 0037067666 scopus 로고    scopus 로고
    • The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways
    • Fryer, L. G.; Parbu-Patel, A.; Patel, A. The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways J. Biol. Chem. 2002, 277, 25226-25232
    • (2002) J. Biol. Chem. , vol.277 , pp. 25226-25232
    • Fryer, L.G.1    Parbu-Patel, A.2    Patel, A.3
  • 22
    • 0034141355 scopus 로고    scopus 로고
    • The regulation of AMP-activated protein kinase by phosphorylation
    • Stein, S. C.; Woods, A.; Jones, N. A.; Davison, M. D.; Carling, D. The regulation of AMP-activated protein kinase by phosphorylation Biochem. J. 2000, 345, 437-443
    • (2000) Biochem. J. , vol.345 , pp. 437-443
    • Stein, S.C.1    Woods, A.2    Jones, N.A.3    Davison, M.D.4    Carling, D.5
  • 23
  • 24
    • 47849123027 scopus 로고    scopus 로고
    • Effects of Momordica charantia on insulin resistance and visceral obesity in mice on high-fat diet
    • Shih, C. C.; Lin, C. H.; Lin, W. L. Effects of Momordica charantia on insulin resistance and visceral obesity in mice on high-fat diet Diabetes Res. Clin. Pract. 2008, 81, 134-143
    • (2008) Diabetes Res. Clin. Pract. , vol.81 , pp. 134-143
    • Shih, C.C.1    Lin, C.H.2    Lin, W.L.3
  • 25
    • 78649637009 scopus 로고    scopus 로고
    • Eriobotrya japonica improves hyperlipidaemia and reverses insulin resistance in high-fat-fed mice
    • Shih, C. C.; Lin, C. H.; Wu, J. B. Eriobotrya japonica improves hyperlipidaemia and reverses insulin resistance in high-fat-fed mice Phytother. Res. 2010, 24, 1769-1780
    • (2010) Phytother. Res. , vol.24 , pp. 1769-1780
    • Shih, C.C.1    Lin, C.H.2    Wu, J.B.3
  • 26
    • 84875592476 scopus 로고    scopus 로고
    • Cell suspension culture of Eriobotrya japonica regulates the diabetic and hyperlipidemic signs of high-fat-fed mice
    • Shih, C. C.; Ciou, J. L.; Lin, C. H.; Wu, J. B.; Ho, H. Y. Cell suspension culture of Eriobotrya japonica regulates the diabetic and hyperlipidemic signs of high-fat-fed mice Molecules 2013a, 18, 2726-2753
    • (2013) Molecules , vol.18 , pp. 2726-2753
    • Shih, C.C.1    Ciou, J.L.2    Lin, C.H.3    Wu, J.B.4    Ho, H.Y.5
  • 27
    • 84908568650 scopus 로고    scopus 로고
    • Tormentic acid, a major component of suspension cells of Eriobotrya japonica, suppresses high-fat diet-induced diabetes and hyperlipidemia by glucose transporter 4 and AMP-activated protein kinase phosphorylation
    • Wu, J. B.; Kuo, Y. H.; Lin, C. H.; Ho, Y. H.; Shih, C. C. Tormentic acid, a major component of suspension cells of Eriobotrya japonica, suppresses high-fat diet-induced diabetes and hyperlipidemia by glucose transporter 4 and AMP-activated protein kinase phosphorylation J. Agric. Food Chem. 2014, 62, 10717-10726
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 10717-10726
    • Wu, J.B.1    Kuo, Y.H.2    Lin, C.H.3    Ho, Y.H.4    Shih, C.C.5
  • 28
    • 64549141112 scopus 로고    scopus 로고
    • Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructose-fed rats
    • Shih, C. C.; Lin, C. H.; Lin, W. L.; Wu, J. B. Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructose-fed rats J. Ethnopharmacol. 2009, 123, 82-90
    • (2009) J. Ethnopharmacol. , vol.123 , pp. 82-90
    • Shih, C.C.1    Lin, C.H.2    Lin, W.L.3    Wu, J.B.4
  • 29
    • 11844254843 scopus 로고    scopus 로고
    • Fenofibrate treatment is associated with better glycemic control and lower serum leptin and insulin levels in type 2 diabetic patients with hypertriglyceridemia
    • Damci, T.; Tatliagac, S.; Osar, Z.; Ilkova, H. Fenofibrate treatment is associated with better glycemic control and lower serum leptin and insulin levels in type 2 diabetic patients with hypertriglyceridemia Eur. J. Inter. Med. 2003, 14, 357-360
    • (2003) Eur. J. Inter. Med. , vol.14 , pp. 357-360
    • Damci, T.1    Tatliagac, S.2    Osar, Z.3    Ilkova, H.4
  • 30
    • 2542528670 scopus 로고    scopus 로고
    • A family with severe insulin resistance and diabetes due to a mutation in AKT2
    • George, S.; Rochford, J. J.; Wolfrum, C. A family with severe insulin resistance and diabetes due to a mutation in AKT2 Science 2004, 304, 1325-1328
    • (2004) Science , vol.304 , pp. 1325-1328
    • George, S.1    Rochford, J.J.2    Wolfrum, C.3
  • 31
    • 1942453616 scopus 로고    scopus 로고
    • Glycolysis and glyconeogenesis
    • Berg, J. M. Tymoczko, J. L. Freeman: New York
    • Berg, J. M.; Tymoczko, J. L.; Stryer, L. Glycolysis and glyconeogenesis. In Stryer Biochemistry; Berg, J. M.; Tymoczko, J. L., Eds.; Freeman: New York, 2001; pp 425-464.
    • (2001) Stryer Biochemistry , pp. 425-464
    • Berg, J.M.1    Tymoczko, J.L.2    Stryer, L.3
  • 32
    • 0036097775 scopus 로고    scopus 로고
    • Intrahepatic mechanisms underlying the effect of metformin in decreasing basal glucose production in rats fed a high-fat diet
    • Mithieux, G.; Guignot, L.; Bordet, J. C.; Wiernsperger, N. Intrahepatic mechanisms underlying the effect of metformin in decreasing basal glucose production in rats fed a high-fat diet Diabetes 2002, 51, 139-143
    • (2002) Diabetes , vol.51 , pp. 139-143
    • Mithieux, G.1    Guignot, L.2    Bordet, J.C.3    Wiernsperger, N.4
  • 35
    • 0035065450 scopus 로고    scopus 로고
    • Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice
    • Patel, D. D.; Knight, B. L.; Wiggins, D.; Humphreys, S. M.; Gibbons, G. F. Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice J. Lipid Res. 2001, 42, 328-337
    • (2001) J. Lipid Res. , vol.42 , pp. 328-337
    • Patel, D.D.1    Knight, B.L.2    Wiggins, D.3    Humphreys, S.M.4    Gibbons, G.F.5
  • 36
    • 0035914356 scopus 로고    scopus 로고
    • Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
    • Cases, S.; Stone, S. J.; Zhou, P.; Yen, E.; Tow, B.; Lardizabal, K. D.; Voelker, T.; Farese, R. V., Jr. Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members J. Biol. Chem. 2001, 276, 38870-38876
    • (2001) J. Biol. Chem. , vol.276 , pp. 38870-38876
    • Cases, S.1    Stone, S.J.2    Zhou, P.3    Yen, E.4    Tow, B.5    Lardizabal, K.D.6    Voelker, T.7    Farese, R.V.8
  • 38
    • 62149094721 scopus 로고    scopus 로고
    • Fenofibrate ameliorates diabetic and dyslipidemic profiles in KKAy mice partly via down-regulation of 11β-HSD1, PEPCK and DGAT2. Comparison of PPARα, PPARγ, and liver x receptor agonists
    • Srivastava, R. A. K. Fenofibrate ameliorates diabetic and dyslipidemic profiles in KKAy mice partly via down-regulation of 11β-HSD1, PEPCK and DGAT2. Comparison of PPARα, PPARγ, and liver x receptor agonists Eur. J. Pharmacol. 2009, 607, 258-263
    • (2009) Eur. J. Pharmacol. , vol.607 , pp. 258-263
    • Srivastava, R.A.K.1
  • 39
    • 0030829812 scopus 로고    scopus 로고
    • Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene
    • Shimano, H.; Shimomura, I.; Hammer, R. E.; Herz, J.; Goldstein, J. L.; Brown, M. S.; Horton, J. D. Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene J. Clin. Invest. 1997, 100, 2115-2124
    • (1997) J. Clin. Invest. , vol.100 , pp. 2115-2124
    • Shimano, H.1    Shimomura, I.2    Hammer, R.E.3    Herz, J.4    Goldstein, J.L.5    Brown, M.S.6    Horton, J.D.7
  • 40
    • 23644456172 scopus 로고    scopus 로고
    • Therapeutic roles of peroxisome proliferator-activated receptor agonists
    • Staeles, B.; Fruchart, J. C. Therapeutic roles of peroxisome proliferator-activated receptor agonists Diabetes 2005, 54, 2460-2470
    • (2005) Diabetes , vol.54 , pp. 2460-2470
    • Staeles, B.1    Fruchart, J.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.