Transcription factor C/EBPα-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia

Blood

Volumn 122, Issue 14, 2013, Pages 2433-2442

  Katzerke, Christiane ^a   Madan, Vikas ^b   Gerloff, Dennis ^a   Bräuer Hartmann, Daniela ^a   Hartmann, Jens Uwe ^a   Wurm, Alexander Arthur ^a   Müller Tidow, Carsten ^c   Schnittger, Susanne ^d   Tenen, Daniel G ^b,e   Niederwieser, Dietger ^a   Behre, Gerhard ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c UNIVERSITY OF MÜNSTER   (Germany)

^d MLL MUNICH LEUKEMIA LABORATORY   (Germany)

^e HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; MICRORNA; MICRORNA 30C; NOTCH1 RECEPTOR; UNCLASSIFIED DRUG;

ACUTE MYELOID LEUKEMIA; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; COMPUTER MODEL; CONTROLLED STUDY; GENE INACTIVATION; GENE MUTATION; GENE TARGETING; GRANULOCYTE; GRANULOPOIESIS; HUMAN; HUMAN CELL; KARYOTYPE; LUCIFERASE ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL; CHROMATIN IMMUNOPRECIPITATION; CYTOLOGY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; IMMUNOBLOTTING; KNOCKOUT MOUSE; LEUKOPOIESIS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GRANULOCYTES; HUMANS; IMMUNOBLOTTING; LEUKEMIA, MYELOID, ACUTE; LEUKOPOIESIS; MICE; MICE, KNOCKOUT; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, NOTCH1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION;

EID: 84887776468     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-12-472183     Document Type: Article

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