Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 92, Issue , 2015, Pages 65-73

  Water, Jorrit Jeroen ^a   Smart, Simon ^a,b   Franzyk, Henrik ^a   Foged, Camilla ^a   Nielsen, Hanne Mørck ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b University of Bath   (United Kingdom)

Author keywords

A549; Antibiotics; Antimicrobial peptide; Calu 3; Infected epithelial cells; PLGA; Polymeric nanoparticles; Pulmonary drug delivery; Staphylococcus aureus; THP 1

Indexed keywords

PLECTASIN; POLYGLACTIN; ANTIINFECTIVE AGENT; DRUG CARRIER; EMULSION; LACTIC ACID; NANOPARTICLE; PEPTIDE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; SOLVENT;

ARTICLE; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; EC50; EPITHELIUM CELL; EVAPORATION; FREEZE DRYING; HUMAN; HUMAN CELL; MACROPHAGE; NANOEMULSION; NONHUMAN; PARTICLE SIZE; RESPIRATORY EPITHELIUM; SCANNING ELECTRON MICROSCOPY; STAPHYLOCOCCUS AUREUS; ZETA POTENTIAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; EMULSION; METABOLISM; TIME;

ANTI-BACTERIAL AGENTS; CELL LINE; CELL SURVIVAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; EMULSIONS; EPITHELIAL CELLS; HUMANS; LACTIC ACID; MACROPHAGES; NANOPARTICLES; PEPTIDES; POLYGLYCOLIC ACID; SOLVENTS; STAPHYLOCOCCUS AUREUS; TIME FACTORS;

EID: 84924427850     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.02.009     Document Type: Article

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