Population dynamics of persistent Staphylococcus aureus isolated from the airways of cystic fibrosis patients during a 6-year prospective study

Journal of Clinical Microbiology

Volumn 41, Issue 9, 2003, Pages 4424-4427

  Kahl, Barbara C ^a,d   Duebbers, Angelika ^a   Lubritz, Gabriele ^a   Haeberle, Johannes ^a   Koch, Hans G ^a   Ritzerfeld, Barbara ^a   Reilly, Marion ^a   Harms, Erik ^a   Proctor, Richard A ^c   Herrmann, Mathias ^b   Peters, Georg ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COTRIMOXAZOLE;

ADOLESCENT; ADULT; AIRWAY; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CHILD; CONTROLLED STUDY; CYSTIC FIBROSIS; DYNAMICS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; MOLECULAR TYPING; PHENOTYPE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PULSED FIELD GEL ELECTROPHORESIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; ELECTROPHORESIS, GEL, PULSED-FIELD; FEMALE; HUMANS; INFANT; MALE; PHARYNX; PROSPECTIVE STUDIES; SPUTUM; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STRAWBERRY CRINKLE VIRUS;

EID: 0041417802     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.41.9.4424-4427.2003     Document Type: Article

References (25)

1. Balwit, J. M., P. van Langefelde, J. M. Vann, and R. A. Proctor. 1994. Gentamicin-resistant menadione and hemin auxotrophic Staphylococcus aureus persist within cultured endothelial cells. J. Infect. Dis. 170:1033-1037.
2. Bayles, K. W., C. A. Wesson, L. E. Liou, L. K. Fox, G. A. Bohach, and W. R. Trumble. 1998. Intracellular Staphylococcus aureus escapes the endosome and induces apoptosis in epithelial cells. Infect. Immun. 66:363-372.
3. Branger C., C. Gardye, and N. Lambert-Zechovsky. 1996. Persistence of Staphylococcus aureus strains among cystic fibrosis patients over extended periods of time. J. Med. Microbiol. 45:294-301.
4. Burns, J. L., J. Emerson, J. R. Stapp, D. L. Yim, J. Krzewinski, L. Louden, B. W. Ramsey, and C. R. Clausen. 1998. Microbiology of sputum from patients at cystic fibrosis centers in the United States. Clin. Infect. Dis. 27:158-163.
5. Cystic Fibrosis Foundation. 1999. Patient registry 1998 annual data report. Cystic Fibrosis Foundation, Bethesda, Md.
6. Goering, R. V., and M. A. Winters. 1992. Rapid method for epidemiological evaluation of gram-positive cocci by field inversion gel electrophoresis. J. Clin. Microbiol. 30:577-580.
7. Goerke, C., K. Kraning, M. Stern, G. Döring, K. Botzenhart, and C. Wolz. 2000. Molecular epidemiology of community-acquired Staphylococcus aureus in families with and without cystic fibrosis. J. Infect. Dis. 181:984-989.
8. Hoff, G. E., and N. Hoiby. 1975. Staphylococcus aureus in cystic fibrosis: antibiotic sensitivity and phage types during the latest decade. Acta Pathol. Microbiol. Scand. Sect. B 83:219-225.
9. Hudson, M. C., W. K. Ramp, N. C. Nicholson, A. S. Williams, and M. T. Nousiainen. 1995. Internalization of Staphylococcus aureus by cultured osteoblasts. Microb. Pathog. 19:409-419.
10. Kahl, B., M. Herrmann, A. Schulze Everding, H. G. Koch, K. Becker, E. Harms, R. A. Proctor, and G. Peters. 1998. Persistent infection with small colony variant strains of Staphylococcus aureus in patients with cystic fibrosis. J. Infect. Dis. 177:1023-1029.
11. Kahl, B. C., G. Belling, R. Reichelt, M. Herrmann, R. A. Proctor, and G. Peters. 2003. Thymidine-dependent small-colony variants of Staphylococcus aureus exhibit gross morphological and ultrastructural changes consistent with impaired cell separation. J. Clin. Microbiol. 41:410-413.
12. Kahl, B. C., M. Goulian, W. van Wamel, M. Herrmann, S. M. Simon, G. Kaplan, G. Peters, and A. L. Cheung. 2000. Staphylococcus aureus RN6390 replicates and induces apoptosis in a pulmonary epithelial cell line. Infect. Immun. 68:5385-5392.
13. Knowles, M. R., P. H. Gilligan, and R. C. Boucher. 2000. Cystic fibrosis, p. 767-772. In G. L. Mandell, J. E. Bennett, and R. Dolin (ed.), Principles and practice of infectious diseases 5th ed. Churchill Livingstone, New York, N.Y.
14. Mahenthiralingam, E., M. E. Campbell, J. Foster, J. S. Lam, and D. P. Speert. 1996. Random amplified polymorphic DNA typing of Pseudomonas aeruginosa isolates recovered from patients with cystic fibrosis. J. Clin. Microbiol. 34:1129-1135.
15. Proctor, R. A., P. van Langefelde, M. Kristjansson, J. N. Maslow, and R. D. Arbeit. 1995. Persisting and relapsing infections associated with small-colony variants of Staphylococcus aureus. Clin. Infect. Dis. 20:95-102.
16. Renders, N. H. M., A. van Belkum, S. E. Overbeek, J. W. Mouton, and H. A. Verbrugh. 1997. Molecular epidemiology of Staphylococcus aureus strains colonizing the lungs of related and unrelated cystic fibrosis patients. Clin. Microbiol. Infect. 3:216-221.
17. Roemling, U., B. Fiedler, J. Bosshammer, D. Grothues, J. Greipel, H. von der Hardt, and B. Tuemmler. 1994. Epidemiology of chronic Pseudomonas aeruginosa infections in cystic fibrosis. J. Infect. Dis. 170:1616-1621.
18. Rosenfeld, M., J. Emerson, F. Accurso, D. Armstrong, R. Castile, K. Grimwood, P. Hiatt, K. McCoy, S. McNamara, B. Ramsey, and J. Wagener. 1999. Diagnostic accuracy of oropharyngeal cultures in infants and young children with cystic fibrosis. Pediatr. Pulmonol. 28:321-328.
19. 1. Cell. Microbiol. 1:101-117.
20. Struelens, M. J. 1996. Consensus guidelines for appropriate use and evaluation of microbial epidemiologic typing systems. Clin. Microbiol. Infect. 2:2-11.
21. Tenover, F. C., R. D. Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33:2233-2239.
22. von Eiff, C., K. Becker, D. Metze, G. Lubritz, J. Hockmann, T. Schwarz, and G. Peters. 2001. Intracellular persistence of Staphylococcus aureus small-colony variants within keratinocytes: a cause for antibiotic treatment failure in a patient with Darier's disease. Clin. Infect. Dis. 32:1643-1647.
23. von Eiff, C., D. Bettin, R. A. Proctor, B. Rolaufs, N. Lindner, W. Winkelmann, and G. Peters. 1997. Recovery of small colony variants of Staphylococcus aureus following gentamicin bead placement for osteomyelitis. Clin. Infect. Dis. 25:1250-1251.
24. von Eiff, C., C. Heilmann, R. A. Proctor, C. Wolz, G. Peters, and F. Goetz. 1997. A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly. J. Bacteriol. 179:4706-4712.
25. von Eiff, C., P. E. Vaudaux, B. C. Kahl, D. P. Lew, S. Emler, A. Schmidt, G. Peters, and R. A. Proctor. 1999. Bloodstream infections caused by small-colony variants of coagulase-negative staphylococci following pacemaker implantation. Clin. Infect. Dis. 29:932-934.