Cellular pharmacokinetics and intracellular activity against Listeria monocytogenes and Staphylococcus aureus of chemically modified and nanoencapsulated gentamicin

Journal of Antimicrobial Chemotherapy

Volumn 67, Issue 9, 2012, Pages 2158-2164

  Imbuluzqueta, Edurne ^a   Lemaire, Sandrine ^b   Gamazo, Carlos ^a   Elizondo, Elisa ^c,d   Ventosa, Nora ^c,d   Veciana, Jaume ^c,d   Van bambeke, Françoise ^b   Blanco Prieto, María J ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c INSTITUT DE CIÈNCIA DE MATERIALS DE BARCELONA ICMAB CSIC   (Spain)

^d BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

Drug accumulation; Intracellular bacteria; Nanoparticles; Subcellular distribution

Indexed keywords

GENTAMICIN; NANOPARTICLE; POLYGLACTIN;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; CELL LEVEL; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; INCUBATION TIME; LISTERIA; LISTERIA MONOCYTOGENES; MACROPHAGE; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; MONOCYTE; NANOENCAPSULATION; NONHUMAN; PHAGOCYTE; PHAGOLYSOSOME; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL LINE; GENTAMICINS; HUMANS; LISTERIA MONOCYTOGENES; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; NANOPARTICLES; STAPHYLOCOCCUS AUREUS;

EID: 84865398530     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks172     Document Type: Article

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