Metal-free arylation of ethyl acetoacetate with hypervalent diaryliodonium salts: An immediate access to diverse 3-aryl-4(1 H)-quinolones

Journal of Organic Chemistry

Volumn 80, Issue 5, 2015, Pages 2513-2520

  Monastyrskyi, Andrii ^a   Namelikonda, Niranjan K ^a   Manetsch, Roman ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; CHEMICAL REACTIONS; SYNTHESIS (CHEMICAL);

ANTIMALARIAL COMPOUNDS; ARYLATIONS; DIARYLIODONIUM SALTS; ETHYLACETOACETATE; IODONIUM SALTS; METAL FREE; METAL-FREE CONDITIONS; PRECLINICAL DEVELOPMENT;

SALTS;

(4 NITROPHENYL)(PHENYL)IODONIUM TETRAFLUOROBORATE; (6 CHLOROPYRIDIN 3 YL)(PHENYL)IODONIUM TRIFLUOROMETHANESULFONATE; 2 (2 FLUOROPHENYL) 3 OXOBUTANOATE; 2 (2,4 DIMETHYLPHENYL) 3 OXOBUTANOATE; 2 (4 CHLOROPHENYL) 3 OXOBUTANOATE; 2 [4 (TERT BUTYL)PHENYL] 3 OXOBUTANOATE; 3 ARYL 4(1H) QUINOLONE DERIVATIVE; 3 HYDROXY 2 MESITYLBUT 2 ENOATE; 3 OXO 2 [4 (TRIFLUOROMETHYL)PHENYL]BUTANOATE; ACETOACETIC ACID; ANTIMALARIAL AGENT; BIS(2 FLUOROPHENYL)IODONIUM TETRAFLUOROBORATE; BIS(2,4 DIMETHYLPHENYL)IODONIUM TRIFLUOROMETHANESULFONATE; BIS(4 CHLOROPHENYL)IODONIUM TETRAFLUOROBORATE; BIS[4 (METHOXYCARBONYL)PHENYL]IODONIUM TETRAFLUOROBORATE; BIS[4 (TERT BUTYL)PHENYL]IODONIUM TRIFLUOROMETHANESULFONATE; BIS[4 (TRIFLUOROMETHYL)PHENYL]IODONIUM TETRAFLUOROBORATE; DI O TOLYLIODONIUM TETRAFLUOROBORATE; DIMESITYLIODONIUM TRIFLUOROMETHANESULFONATE; DIPHENYLIODONIUM SALT; DIPHENYLIODONIUM TETRAFLUOROBORATE; ELQ 300; ETHYL 3 OXO 2 (O TOLYL)BUTANOATE; ETHYL 3 OXO 2 PHENYLBUTANOATE; ETHYL ACETOACETATE; MESITYL(PHENYL)IODONIUM TRIFLUOROMETHANESULFONATE; METAL; PHENYL[4 (TRIFLUOROMETHYL)PHENYL]IODONIUM TRIFLUOROMETHANESULFONATE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; 6-CHLORO-7-METHOXY-2-METHYL-3-(4-(4-(TRIFLUOROMETHOXY)PHENOXY)PHENYL)QUINOLIN-4(1H)-ONE; ACETOACETIC ACID DERIVATIVE; CATION; IODINE; QUINOLINE DERIVATIVE;

ARTICLE; ARYLATION; CATALYST; CRYSTALLIZATION; CYCLIZATION; DRUG SYNTHESIS; ELECTRONICS; ELECTROPHILICITY; NUCLEOPHILICITY; PROTON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CHEMISTRY; SYNTHESIS;

ACETOACETATES; ANTIMALARIALS; IODINE; METALS; MOLECULAR STRUCTURE; ONIUM COMPOUNDS; QUINOLINES; QUINOLONES;

EID: 84924325586     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo5023958     Document Type: Article

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