Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells

BMC Complementary and Alternative Medicine

Volumn 14, Issue 1, 2014, Pages

  Lim, Su Wen ^a   Loh, Hwei San ^a   Ting, Kang Nee ^a   Bradshaw, Tracey D ^b   Zeenathul, Nazariah A ^c  

^a UNIVERSITY OF NOTTINGHAM MALAYSIA CAMPUS   (Malaysia)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Apoptosis; Bax; Bid; Caspase 8; Cytochrome c; Cytotoxicity; DNA damage; Mitochondrial membrane permeability; Tocotrienol isomers

Indexed keywords

ALPHA TOCOTRIENOL; CASPASE 8; CYTOCHROME C; DELTA TOCOTRIENOL; GAMMA TOCOTRIENOL; PROTEIN BAX; PROTEIN BID; TOCOPHEROL; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BAX PROTEIN, HUMAN; BID PROTEIN, HUMAN; CHROMAN DERIVATIVE; PLASTOCHROMANOL 8; TOCOTRIENOL, ALPHA; TOCOTRIENOL, DELTA;

A549 CELL LINE; APOPTOSIS; ARTICLE; BRAIN CANCER; CANCER CELL; CELL CYCLE G1 PHASE; CELL CYCLE PHASE; CELL STRUCTURE; CELL VIABILITY; COMET ASSAY; CONCENTRATION RESPONSE; DNA DAMAGE; DNA FRAGMENTATION; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; ENZYME RELEASE; FLOW; HUMAN; HUMAN CELL; INCIDENCE; ISOMER; MITOCHONDRIAL MEMBRANE; PERMEABILITY; SINGLE STRANDED DNA BREAK; ADENOCARCINOMA; ANALOGS AND DERIVATIVES; CELL CYCLE; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM NEOPLASMS; COMPARATIVE STUDY; DRUG EFFECTS; GLIOBLASTOMA; ISOMERISM; LUNG NEOPLASMS; METABOLISM; MITOCHONDRION; TUMOR CELL LINE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 8; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM NEOPLASMS; CHROMANS; CYTOCHROMES C; DNA FRAGMENTATION; GLIOBLASTOMA; HUMANS; ISOMERISM; LUNG NEOPLASMS; MITOCHONDRIA; TOCOTRIENOLS; VITAMIN E;

EID: 84924325389     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-469     Document Type: Article

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