Receptor-interacting protein kinase 3 contributes to abdominal aortic aneurysms via smooth muscle cell necrosis and inflammation

Circulation Research

Volumn 116, Issue 4, 2015, Pages 600-611

  Wang, Qiwei ^a,b   Liu, Zhenjie ^a,c   Ren, Jun ^a   Morgan, Stephanie ^a   Assa, Carmel ^a   Liu, Bo ^a,b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Abdominal; Aortic aneurysm; Apoptosis; Mouse; Myocytes; Necrosis; Nuclear factor kappa B; Protein kinase C delta; Rip3 protein; Smooth muscle

Indexed keywords

PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN KINASE 1; RECEPTOR INTERACTING PROTEIN KINASE 3; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; PANCREATIC ELASTASE; PRKCD PROTEIN, MOUSE; PROTEIN KINASE C DELTA; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RELA PROTEIN, MOUSE; RIPK3 PROTEIN, HUMAN; RIPK3 PROTEIN, MOUSE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY WALL; ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE DOSAGE; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; MALE; MOUSE; NECROPTOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER; ABDOMINAL AORTA; ANIMAL; AORTIC ANEURYSM, ABDOMINAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; KNOCKOUT MOUSE; METABOLISM; NECROSIS; PATHOLOGY; RNA INTERFERENCE; SMOOTH MUSCLE CELL; TRANSPLANTATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NECROSIS; PANCREATIC ELASTASE; PROTEIN KINASE C-DELTA; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RNA INTERFERENCE; TRANSCRIPTION FACTOR RELA; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84924267038     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.304899     Document Type: Article

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