Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage

Aging Cell

Volumn 14, Issue 2, 2015, Pages 162-169

  Gibbs Seymour, Ian ^a,b   Markiewicz, Ewa ^a   Bekker Jensen, Simon ^b   Mailand, Niels ^b   Hutchison, Christopher J ^a  

^a DURHAM UNIVERSITY   (United Kingdom)

^b University of Copenhagen   (Denmark)

Author keywords

53BP1; DNA damage response; Laminopathy; Lamins

Indexed keywords

53BP1 PROTEIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BINDING PROTEIN; CATHEPSIN L; DEOXYRIBONUCLEASE I; LAMIN A; LAMIN C; UNCLASSIFIED DRUG; LMNA PROTEIN, HUMAN; PROTEIN BINDING; SIGNAL PEPTIDE; TP53BP1 PROTEIN, HUMAN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE ARREST; CELL SURVIVAL; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FLUORESCENCE MICROSCOPY; GENOMIC INSTABILITY; HETEROCHROMATIN; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IONIZING RADIATION; NUCLEAR LAMINA; NULL CELL; OLIGOMERIZATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SKIN FIBROBLAST; U2OS CELL LINE; CYTOLOGY; FIBROBLAST; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

CELL LINE, TUMOR; DNA DAMAGE; DNA REPAIR; FIBROBLASTS; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LAMIN TYPE A; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84924260738     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12258     Document Type: Article

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