-
1
-
-
34250020201
-
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
-
El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. 2007; 132:2557-2576.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
3
-
-
79751492851
-
NF-kappaB in the liver-linking injury, fibrosis and hepatocellular carcinoma
-
Luedde T, Schwabe RF. NF-kappaB in the liver-linking injury, fibrosis and hepatocellular carcinoma. Nature reviews Gastroenterology & hepatology. 2011; 8:108-118.
-
(2011)
Nature reviews Gastroenterology & hepatology
, vol.8
, pp. 108-118
-
-
Luedde, T.1
Schwabe, R.F.2
-
4
-
-
70350104779
-
SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis
-
e1811-1810
-
Calvisi DF, Ladu S, Pinna F, Frau M, Tomasi ML, Sini M, Simile MM, Bonelli P, Muroni MR, Seddaiu MA, Lim DS, Feo F, Pascale RM. SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis. Gastroenterology. 2009; 137:1816-1826. e1811-1810.
-
(2009)
Gastroenterology
, vol.137
, pp. 1816-1826
-
-
Calvisi, D.F.1
Ladu, S.2
Pinna, F.3
Frau, M.4
Tomasi, M.L.5
Sini, M.6
Simile, M.M.7
Bonelli, P.8
Muroni, M.R.9
Seddaiu, M.A.10
Lim, D.S.11
Feo, F.12
Pascale, R.M.13
-
5
-
-
77952575909
-
PTEN in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and cancer
-
Peyrou M, Bourgoin L, Foti M. PTEN in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and cancer. Digestive diseases (Basel, Switzerland). 2010; 28:236-246.
-
(2010)
Digestive diseases (Basel, Switzerland)
, vol.28
, pp. 236-246
-
-
Peyrou, M.1
Bourgoin, L.2
Foti, M.3
-
6
-
-
79952043062
-
Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad
-
Nejak-Bowen KN, Monga SP. Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad. Seminars in cancer biology. 2011; 21:44-58.
-
(2011)
Seminars in cancer biology
, vol.21
, pp. 44-58
-
-
Nejak-Bowen, K.N.1
Monga, S.P.2
-
7
-
-
77956627711
-
The role of signaling pathways in the development and treatment of hepatocellular carcinoma
-
Whittaker S, Marais R, Zhu AX. The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene. 2010; 29:4989-5005.
-
(2010)
Oncogene
, vol.29
, pp. 4989-5005
-
-
Whittaker, S.1
Marais, R.2
Zhu, A.X.3
-
8
-
-
84905993912
-
beta-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
-
Mokkapati S, Niopek K, Huang L, Cunniff KJ, Ruteshouser EC, deCaestecker M, Finegold MJ, Huff V. beta-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma. Cancer research. 2014; 74:4515-4525.
-
(2014)
Cancer research
, vol.74
, pp. 4515-4525
-
-
Mokkapati, S.1
Niopek, K.2
Huang, L.3
Cunniff, K.J.4
Ruteshouser, E.C.5
deCaestecker, M.6
Finegold, M.J.7
Huff, V.8
-
10
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 1997; 275:1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
11
-
-
34249061491
-
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
-
Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science. 2007; 316:1043-1046.
-
(2007)
Science
, vol.316
, pp. 1043-1046
-
-
Major, M.B.1
Camp, N.D.2
Berndt, J.D.3
Yi, X.4
Goldenberg, S.J.5
Hubbert, C.6
Biechele, T.L.7
Gingras, A.C.8
Zheng, N.9
Maccoss, M.J.10
Angers, S.11
Moon, R.T.12
-
12
-
-
0035844886
-
Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation
-
Persad S, Troussard AA, McPhee TR, Mulholland DJ, Dedhar S. Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation. J Cell Biol. 2001; 153:1161-1174.
-
(2001)
J Cell Biol
, vol.153
, pp. 1161-1174
-
-
Persad, S.1
Troussard, A.A.2
McPhee, T.R.3
Mulholland, D.J.4
Dedhar, S.5
-
13
-
-
70350448825
-
Nuclear-cytoplasmic shuttling of menin regulates nuclear translocation of {beta}-catenin
-
Cao Y, Liu R, Jiang X, Lu J, Jiang J, Zhang C, Li X, Ning G. Nuclear-cytoplasmic shuttling of menin regulates nuclear translocation of {beta}-catenin. Mol Cell Biol. 2009; 29:5477-5487.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5477-5487
-
-
Cao, Y.1
Liu, R.2
Jiang, X.3
Lu, J.4
Jiang, J.5
Zhang, C.6
Li, X.7
Ning, G.8
-
14
-
-
77956668326
-
MicroRNA roles in beta-catenin pathway
-
Huang K, Zhang JX, Han L, You YP, Jiang T, Pu PY, Kang CS. MicroRNA roles in beta-catenin pathway. Mol Cancer. 2010; 9:252.
-
(2010)
Mol Cancer
, vol.9
, pp. 252
-
-
Huang, K.1
Zhang, J.X.2
Han, L.3
You, Y.P.4
Jiang, T.5
Pu, P.Y.6
Kang, C.S.7
-
15
-
-
84905503012
-
Therapeutic targeting of microRNAs: current status and future challenges
-
Li Z, Rana TM. Therapeutic targeting of microRNAs: current status and future challenges. Nature reviews Drug discovery. 2014; 13:622-638.
-
(2014)
Nature reviews Drug discovery
, vol.13
, pp. 622-638
-
-
Li, Z.1
Rana, T.M.2
-
16
-
-
84896728397
-
Downregulation of miR-200a induces EMT phenotypes and CSC-like signatures through targeting the beta-catenin pathway in hepatic oval cells
-
Liu J, Ruan B, You N, Huang Q, Liu W, Dang Z, Xu W, Zhou T, Ji R, Cao Y, Li X, Wang D, Tao K, Dou K. Downregulation of miR-200a induces EMT phenotypes and CSC-like signatures through targeting the beta-catenin pathway in hepatic oval cells. PloS one. 2013; 8:e79409.
-
(2013)
PloS one
, vol.8
-
-
Liu, J.1
Ruan, B.2
You, N.3
Huang, Q.4
Liu, W.5
Dang, Z.6
Xu, W.7
Zhou, T.8
Ji, R.9
Cao, Y.10
Li, X.11
Wang, D.12
Tao, K.13
Dou, K.14
-
17
-
-
48649099908
-
Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer
-
Nagel R, le Sage C, Diosdado B, van der Waal M, Oude Vrielink JA, Bolijn A, Meijer GA, Agami R. Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer research. 2008; 68:5795-5802.
-
(2008)
Cancer research
, vol.68
, pp. 5795-5802
-
-
Nagel, R.1
le Sage, C.2
Diosdado, B.3
van der Waal, M.4
Oude Vrielink, J.A.5
Bolijn, A.6
Meijer, G.A.7
Agami, R.8
-
18
-
-
67651102656
-
Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein
-
Bouteille N, Driouch K, Hage PE, Sin S, Formstecher E, Camonis J, Lidereau R, Lallem F. Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein. Oncogene. 2009; 28:2569-2580.
-
(2009)
Oncogene
, vol.28
, pp. 2569-2580
-
-
Bouteille, N.1
Driouch, K.2
Hage, P.E.3
Sin, S.4
Formstecher, E.5
Camonis, J.6
Lidereau, R.7
Lallem, F.8
-
20
-
-
84896532358
-
miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/beta-catenin/BCL9 pathway
-
Zhao JJ, Lin J, Zhu D, Wang X, Brooks D, Chen M, Chu ZB, Takada K, Ciccarelli B, Admin S, Tao J, Tai YT, Treon S, Pinkus G, Kuo WP, Hideshima T, et al. miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/beta-catenin/BCL9 pathway. Cancer research. 2014; 74:1801-1813.
-
(2014)
Cancer research
, vol.74
, pp. 1801-1813
-
-
Zhao, J.J.1
Lin, J.2
Zhu, D.3
Wang, X.4
Brooks, D.5
Chen, M.6
Chu, Z.B.7
Takada, K.8
Ciccarelli, B.9
Admin, S.10
Tao, J.11
Tai, Y.T.12
Treon, S.13
Pinkus, G.14
Kuo, W.P.15
Hideshima, T.16
-
21
-
-
84899483530
-
MiR-612 suppresses the stemness of liver cancer via Wnt/beta-catenin signaling
-
Tang J, Tao ZH, Wen D, Wan JL, Liu DL, Zhang S, Cui JF, Sun HC, Wang L, Zhou J, Fan J, Wu WZ. MiR-612 suppresses the stemness of liver cancer via Wnt/beta-catenin signaling. Biochemical and biophysical research communications. 2014; 447:210-215.
-
(2014)
Biochemical and biophysical research communications
, vol.447
, pp. 210-215
-
-
Tang, J.1
Tao, Z.H.2
Wen, D.3
Wan, J.L.4
Liu, D.L.5
Zhang, S.6
Cui, J.F.7
Sun, H.C.8
Wang, L.9
Zhou, J.10
Fan, J.11
Wu, W.Z.12
-
22
-
-
84905222850
-
WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies
-
Aldaz CM, Ferguson BW, Abba MC. WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies. Biochimica et biophysica acta. 2014; 1846:188-200.
-
(2014)
Biochimica et biophysica acta
, vol.1846
, pp. 188-200
-
-
Aldaz, C.M.1
Ferguson, B.W.2
Abba, M.C.3
-
23
-
-
84892417754
-
Common Chromosomal Fragile Site Gene WWOX in Metabolic Disorders and Tumors
-
Li J, Liu J, Ren Y, Yang J, Liu P. Common Chromosomal Fragile Site Gene WWOX in Metabolic Disorders and Tumors. International journal of biological sciences. 2014; 10:142-148.
-
(2014)
International journal of biological sciences
, vol.10
, pp. 142-148
-
-
Li, J.1
Liu, J.2
Ren, Y.3
Yang, J.4
Liu, P.5
-
24
-
-
34247273473
-
Targeted deletion of Wwox reveals a tumor suppressor function
-
Aqeilan RI, Trapasso F, Hussain S, Costinean S, Marshall D, Pekarsky Y, Hagan JP, Zanesi N, Kaou M, Stein GS, Lian JB, Croce CM. Targeted deletion of Wwox reveals a tumor suppressor function. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104:3949-3954.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 3949-3954
-
-
Aqeilan, R.I.1
Trapasso, F.2
Hussain, S.3
Costinean, S.4
Marshall, D.5
Pekarsky, Y.6
Hagan, J.P.7
Zanesi, N.8
Kaou, M.9
Stein, G.S.10
Lian, J.B.11
Croce, C.M.12
-
25
-
-
34250826625
-
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo
-
Aqeilan RI, Hagan JP, Aqeilan HA, Pichiorri F, Fong LY, Croce CM. Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo. Cancer research. 2007; 67:5606-5610.
-
(2007)
Cancer research
, vol.67
, pp. 5606-5610
-
-
Aqeilan, R.I.1
Hagan, J.P.2
Aqeilan, H.A.3
Pichiorri, F.4
Fong, L.Y.5
Croce, C.M.6
-
26
-
-
48449090284
-
The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX
-
Aderca I, Moser CD, Veerasamy M, Bani-Hani AH, Bonilla-Guerrero R, Ahmed K, Shire A, Cazanave SC, Montoya DP, Mettler TA, Burgart LJ, Nagorney DM, Thibodeau SN, Cunningham JM, Lai JP, Roberts LR. The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX. Journal of hepatology. 2008; 49:373-383.
-
(2008)
Journal of hepatology
, vol.49
, pp. 373-383
-
-
Aderca, I.1
Moser, C.D.2
Veerasamy, M.3
Bani-Hani, A.H.4
Bonilla-Guerrero, R.5
Ahmed, K.6
Shire, A.7
Cazanave, S.C.8
Montoya, D.P.9
Mettler, T.A.10
Burgart, L.J.11
Nagorney, D.M.12
Thibodeau, S.N.13
Cunningham, J.M.14
Lai, J.P.15
Roberts, L.R.16
-
27
-
-
4344715921
-
Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma
-
Park SW, Ludes-Meyers J, Zimonjic DB, Durkin ME, Popescu NC, Aldaz CM. Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma. British journal of cancer. 2004; 91:753-759.
-
(2004)
British journal of cancer
, vol.91
, pp. 753-759
-
-
Park, S.W.1
Ludes-Meyers, J.2
Zimonjic, D.B.3
Durkin, M.E.4
Popescu, N.C.5
Aldaz, C.M.6
-
28
-
-
84872664583
-
The expression and significance of WWOX and beta-catenin in hepatocellular carcinoma
-
Li YP, Wu CC, Chen WT, Huang YC, Chai CY. The expression and significance of WWOX and beta-catenin in hepatocellular carcinoma. APMIS: acta pathologica, microbiologica, et immunologica Scandinavica. 2013; 121:120-126.
-
(2013)
APMIS: acta pathologica, microbiologica, et immunologica Scandinavica
, vol.121
, pp. 120-126
-
-
Li, Y.P.1
Wu, C.C.2
Chen, W.T.3
Huang, Y.C.4
Chai, C.Y.5
-
29
-
-
84895774982
-
Molecular origin of the binding of WWOX tumor suppressor to ErbB4 receptor tyrosine kinase
-
Schuchardt BJ, Bhat V, Mikles DC, McDonald CB, Sudol M, Farooq A. Molecular origin of the binding of WWOX tumor suppressor to ErbB4 receptor tyrosine kinase. Biochemistry. 2013; 52:9223-9236.
-
(2013)
Biochemistry
, vol.52
, pp. 9223-9236
-
-
Schuchardt, B.J.1
Bhat, V.2
Mikles, D.C.3
McDonald, C.B.4
Sudol, M.5
Farooq, A.6
-
30
-
-
84875259917
-
p73 participates in WWOX-mediated apoptosis in leukemia cells
-
Lin D, Cui Z, Kong L, Cheng F, Xu J, Lan F. p73 participates in WWOX-mediated apoptosis in leukemia cells. International journal of molecular medicine. 2013; 31:849-854.
-
(2013)
International journal of molecular medicine
, vol.31
, pp. 849-854
-
-
Lin, D.1
Cui, Z.2
Kong, L.3
Cheng, F.4
Xu, J.5
Lan, F.6
-
31
-
-
33846196252
-
Physical association with WWOX suppresses c-Jun transcriptional activity
-
Gaudio E, Palamarchuk A, Palumbo T, Trapasso F, Pekarsky Y, Croce CM, Aqeilan RI. Physical association with WWOX suppresses c-Jun transcriptional activity. Cancer research. 2006; 66:11585-11589.
-
(2006)
Cancer research
, vol.66
, pp. 11585-11589
-
-
Gaudio, E.1
Palamarchuk, A.2
Palumbo, T.3
Trapasso, F.4
Pekarsky, Y.5
Croce, C.M.6
Aqeilan, R.I.7
-
32
-
-
78449302631
-
Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours
-
Kim TH, Kim YK, Kwon Y, Heo JH, Kang H, Kim G, An HJ. Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours. Histopathology. 2010; 57:734-743.
-
(2010)
Histopathology
, vol.57
, pp. 734-743
-
-
Kim, T.H.1
Kim, Y.K.2
Kwon, Y.3
Heo, J.H.4
Kang, H.5
Kim, G.6
An, H.J.7
-
33
-
-
84875807408
-
Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer
-
Wu Z, He B, He J, Mao X. Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer. The Prostate. 2013; 73:596-604.
-
(2013)
The Prostate
, vol.73
, pp. 596-604
-
-
Wu, Z.1
He, B.2
He, J.3
Mao, X.4
-
34
-
-
84887196682
-
miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance
-
Zhang L, Pickard K, Jenei V, Bullock MD, Bruce A, Mitter R, Kelly G, Paraskeva C, Strefford J, Primrose J, Thomas GJ, Packham G, Mirnezami AH. miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance. Cancer research. 2013; 73:6435-6447.
-
(2013)
Cancer research
, vol.73
, pp. 6435-6447
-
-
Zhang, L.1
Pickard, K.2
Jenei, V.3
Bullock, M.D.4
Bruce, A.5
Mitter, R.6
Kelly, G.7
Paraskeva, C.8
Strefford, J.9
Primrose, J.10
Thomas, G.J.11
Packham, G.12
Mirnezami, A.H.13
-
35
-
-
84922214693
-
Suppression of AKT expression by miR-153 produced anti-tumor activity in lung cancer
-
[Epub ahead of print]
-
Yuan Y, Du W, Wang Y, Xu C, Wang J, Zhang Y, Wang H, Ju J, Zhao L, Wang Z, Lu Y, Cai B, Pan Z. Suppression of AKT expression by miR-153 produced anti-tumor activity in lung cancer. International journal of cancer Journal international du cancer. 2014; doi: 10.1002/ijc.29103. [Epub ahead of print].
-
(2014)
International journal of cancer Journal international du cancer
-
-
Yuan, Y.1
Du, W.2
Wang, Y.3
Xu, C.4
Wang, J.5
Zhang, Y.6
Wang, H.7
Ju, J.8
Zhao, L.9
Wang, Z.10
Lu, Y.11
Cai, B.12
Pan, Z.13
|