MiR-612 suppresses the stemness of liver cancer via Wnt/β-catenin signaling

Biochemical and Biophysical Research Communications

Volumn 447, Issue 1, 2014, Pages 210-215

  Tang, Jun ^a   Tao, Zhong Hua ^b   Wen, Duo ^a   Wan, Jin Liang ^a   Liu, Dong Li ^a   Zhang, Shu ^a   Cui, Jie Feng ^a   Sun, Hui Chuan ^a   Wang, Lu ^a   Zhou, Jian ^a,c   Fan, Jia ^a,c   Wu, Wei Zhong ^a  

^a ZHONGSHAN HOSPITAL OF FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

Cancer stem cells; Hepatocellular carcinoma; Invasive frontier; miR 612; Wnt catenin

Indexed keywords

AGAR; BETA CATENIN; CISPLATIN; FLUOROURACIL; MICRORNA; MICRORNA 612; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CARCINOGENESIS; CARCINOGENICITY; CLONOGENESIS; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; LIVER CELL CARCINOMA; MALE; METASTASIS; MOUSE; NOD SCID MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR INVASION; TUMOR XENOGRAFT; WNT SIGNALING PATHWAY;

MUS;

CANCER STEM CELLS; HEPATOCELLULAR CARCINOMA; INVASIVE FRONTIER; MIR-612; WNT/Β-CATENIN;

ANIMALS; BETA CATENIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; DRUG RESISTANCE, NEOPLASM; EPITHELIAL-MESENCHYMAL TRANSITION; FLUOROURACIL; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED NOD; MICE, SCID; MICRORNAS; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; WNT SIGNALING PATHWAY;

EID: 84899483530     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.03.135     Document Type: Article

References (18)

1. H.B. El-Serag, and K.L. Rudolph Hepatocellular carcinoma: epidemiology and molecular carcinogenesis Gastroenterology 132 2007 2557 2576
2. P.B. Gupta, C.L. Chaffer, and R.A. Weinberg Cancer stem cells: mirage or reality? Nat. Med. 15 2009 1010 1012
3. D. Bonnet, and J.E. Dick Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat. Med. 3 1997 730 737
4. Z.F. Yang, D.W. Ho, M.N. Ng, C.K. Lau, W.C. Yu, and P. Ngai et al. Significance of CD90+ cancer stem cells in human liver cancer Cancer Cell 13 2008 153 166
5. M. Lagos-Quintana, R. Rauhut, W. Lendeckel, and T. Tuschl Identification of novel genes coding for small expressed RNAs Science 294 2001 853 858
6. I.S. Hsieh, K.C. Chang, Y.T. Tsai, J.Y. Ke, P.J. Lu, and K.H. Lee et al. MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway Carcinogenesis 34 2013 530 538
7. Z.H. Tao, J.L. Wan, L.Y. Zeng, L. Xie, H.C. Sun, and L.X. Qin et al. MiR-612 suppresses the invasive-metastatic cascade in hepatocellular carcinoma J. Exp. Med. 210 2013 789 803
8. I. Malanchi, A. Santamaria-Martinez, E. Susanto, H. Peng, H.R. Lehr, and J.F. Delaloye et al. Tumorsphere - interactions between cancer stem cells and their niche govern metastatic colonization Nature 481 2012 85 89
9. X. Li, Y. Pan, R. Fan, H. Jin, S. Han, and J. Liu et al. Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo Carcinogenesis 29 2008 1587 1593
10. S.F. Tavazoie, C. Alarcon, T. Oskarsson, D. Padua, Q. Wang, and P.D. Bos et al. Endogenous human microRNAs that suppress breast cancer metastasis Nature 451 2008 147 152
11. M. Kim, H. Turnquist, J. Jackson, M. Sgagias, Y. Yan, and M. Gong et al. The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells Clin. Cancer Res. 8 2002 22 28
12. F. Ceteci, S. Ceteci, C. Karreman, B.W. Kramer, E. Asan, and R. Gotz et al. Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-driven murine lung cancer Cancer Cell 12 2007 145 159
13. J. Ji, T. Yamashita, A. Budhu, M. Forgues, H.L. Jia, and C. Li et al. Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells Hepatology 50 2009 472 480
14. S.D. Hatfield, H.R. Shcherbata, K.A. Fischer, K. Nakahara, R.W. Carthew, and H. Ruohola-Baker Stem cell division is regulated by the microRNA pathway Nature 435 2005 974 978
15. T. Yamashita, J. Ji, A. Budhu, M. Forgues, W. Yang, and H.Y. Wang et al. EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features Gastroenterology 136 2009 1012 1024
16. S. Ma, K.W. Chan, L. Hu, T.K. Lee, J.Y. Wo, and N.G. Io et al. Identification and characterization of tumorigenic liver cancer stem/progenitor cells Gastroenterology 132 2007 2542 2556
17. T.K. Lee, A. Castilho, V.C. Cheung, K.H. Tang, S. Ma, and I.O. Ng CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation Cell Stem Cell 9 2011 50 63
18. P.C. Hermann, S.L. Huber, T. Herrler, A. Aicher, J.W. Ellwart, and M. Guba et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer Cell Stem Cell 1 2007 313 323