Mycotoxin zearalenone induces apoptosis in mouse Leydig cells via an endoplasmic reticulum stress-dependent signalling pathway

Reproductive Toxicology

Volumn 52, Issue , 2015, Pages 71-77

  Lin, Pengfei ^a   Chen, Fenglei ^a   Sun, Jin ^a   Zhou, Jinhua ^a   Wang, Xiangguo ^a   Wang, Nan ^a   Li, Xiao ^a   Zhang, Zhe ^a   Wang, Aihua ^a   Jin, YaPing ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Murine Leydig tumour cell line; Primary mouse Leydig cells; Zearalenone

Indexed keywords

4 PHENYLBUTYRIC ACID; CASPASE 12; CASPASE 3; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; SHORT HAIRPIN RNA; TESTOSTERONE; ZEARALENONE; 4-PHENYLBUTYRIC ACID; ARYLBUTYRIC ACID DERIVATIVE; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; SMALL INTERFERING RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; GENE SILENCING; INTRACELLULAR SIGNALING; LEYDIG CELL; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REPRODUCTIVE TOXICITY; TESTOSTERONE SYNTHESIS; TUMOR CELL LINE; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECTS; ENDOPLASMIC RETICULUM; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

FUSARIUM; LENTIVIRUS; MURINAE;

ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; CELL PROLIFERATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HEAT-SHOCK PROTEINS; LEYDIG CELLS; MALE; MICE; PHENYLBUTYRATES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TESTOSTERONE; ZEARALENONE;

EID: 84924244851     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2015.02.007     Document Type: Article

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