Influence of in vitro exposure to mycotoxin zearalenone and its derivatives on swine sperm quality

Reproductive Toxicology

Volumn 25, Issue 4, 2008, Pages 461-467

  Benzoni, E ^a   Minervini, F ^b   Giannoccaro, A ^b   Fornelli, F ^b   Vigo, D ^a   Visconti, A ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b INSTITUTE OF SCIENCES OF FOOD PRODUCTION   (Italy)

Author keywords

Apo BrdU assay; CASA analysis; Flow cytometry; In vitro bioassay; Mycotoxin; SCSA analysis; Sperm quality; Swine spermatozoa

Indexed keywords

ZEARALENONE;

APOPTOSIS; ARTICLE; CELL VIABILITY; CHROMATIN; CONTROLLED STUDY; GENITAL SYSTEM; IN VITRO STUDY; NONHUMAN; REPRODUCTIVE TOXICITY; SPERM; SPERMATOZOON;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CHROMATIN; ESTROGENS, NON-STEROIDAL; MALE; SPERM MOTILITY; SPERMATOZOA; SWINE; ZEARALENONE; ZERANOL;

SUIDAE;

EID: 47249128019     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2008.04.009     Document Type: Article

References (33)

1. Placinta C.M., D'Mello J.P.F., and Mac Donald A.M.C. A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Anim Feed Sci Technol 78 (1999) 21-37
2. Council for Agricultural Science and Technology (CAST). Occurrence of mycotoxins in food and feed. In: CAST, editors. Mycotoxins: risks in plant, animal and human systems. Task Force Report No. 139. Ames, IA: Council for Agricultural Science and Technology; 2003. p. 36-47.
3. European Food Safety Authority (EFSA). Opinion of the scientific panel on contaminants in the food chain on a request from the commission related to zearalenone as undesirable substance in animal feed; 2004. www.efsa.eu.int.
4. Zwierzchowski W., Przybylowcz M., Obremski K., Zielonka L., Skorska-Wyszynska E., Gajecka M., et al. Level of zearalenone in blood serum and lesions in ovarian follicles of sexually immature gilts in the course of zearalenone mycotoxicosis. Pol J Vet Sci 8 (2005) 209-218
5. Malekinejad H., Maas-Bakker R.F., and Fink-Gremmels J. Species differences in the hepatic biotransformation of zearalenone. Vet J 172 (2006) 96-102
6. Minervini F., Giannoccaro A., Cavallini A., and Visconti A. Investigations on cellular proliferation induced by zearalenone and its derivatives in relation to the estrogenic parameters. Toxicol Lett 159 (2005) 272-283
7. Olsen M., Malmlo{combining double acute accent}f H., Pettersson K., Sandholm K., and Kiessling K.H. Plasma and urinary levels of zearalenone and α-zearalenol in a prepubertal gilt fed zearalenone. Acta Pharmacol Toxicol 56 (1985) 239-243
8. Ruhr L.P., Osweiler G.D., and Foley C.W. Effect of the estrogenic mycotoxin zearalenone on reproductive potential in the boar. Am J Vet Res 44 (1983) 483-485
9. Farnworth E.R., and Trenholm H.L. The metabolism of the mycotoxin zearalenone and its effects on the reproductive tracts of young male and female pigs. Can J Anim Sci 63 (1983) 967-975
10. Young L.G., and King G.J. Low concentrations of zearalenone in diets of boars for a prolonged period of time. J Anim Sci 63 (1986) 1197-1200
11. Osweiler G.D. Occurrence and clinical manifestations of trichothecene toxicoses and zearalenone toxicoses. In: Richards J.L., and Thurston J.R. (Eds). Diagnosis of mycotoxicoses (1986), Martinus Nijhoff Publishers 31-42
12. Berger T., Esbenshade K.L., Diekman M.A., Hoagland T., and Tuite J. Influence of prepubertal consumption of zearalenone on sexual development of boars. J Anim Sci 53 (1981) 1559-1564
13. Haschek W.M., and Haliburton J.C. Fusarium monifiorme and zearalenone toxicoses in domestic animals: a review. In: Richards J.L., and Thurston J.R. (Eds). Diagnosis of mycotoxicoses (1986), Martinus Nijhoff Publishers 213-235
14. Boe-Hansen G.B., Morris I.D., Ersboll A.K., Greve T., and Christensen P. DNA integrity in sexed bull sperm assessed by neutral Comet assay and sperm chromatin structure assay. Theriogenology 63 (2005) 1789-1802
15. D'Occhio M.J., Hengstberger K.J., and Johnston S. Biology of sperm chromatin structure and relationship to male fertility and embryonic survival. Anim Reprod Sci 101 (2007) 1-17
16. Gandini L., Lombardo F., Lenzi A., Spanò M., and Dondero F. Cryopreservation and sperm DNA integrity. Cell Tissue Bank 7 (2006) 91-98
17. Peris S.I., Bilodeau J.F., Dufour M., and Bailey JL. Impact of cryopreservation and reactive oxygen species on DNA integrity, lipid peroxidation, and functional parameters in ram sperm. Mol Reprod Dev (2006) 10.1002/mrd
18. Evenson D.P., Larson K.L., and Jost L.K. Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques. J Androl 23 (2002) 25-43
19. Anzar M., He L., Buhr M.M., Kroetsch T.G., and Pauls K.P. Sperm apoptosis in fresh and cryopreserved bull semen detected by flow cytometry and its relationship with fertility. Biol Reprod 66 (2002) 354-360
20. Muratori M., Maggi M., Spinelli S., Filimberti E., Forti G., and Baldi E. Spontaneous DNA fragmentation in swim-up selected human spermatozoa during long term incubation. J Androl 24 (2003) 253-262
21. Sergerie M., Bleau G., Teulé R., Daudin M., and Bujan L. Sperm DNA integrity as diagnosis and prognosis element of male fertility. Gynecol Obstet Fertil 33 (2005) 89-91
22. Betancourt M., Reséndiz A., Casas E., and Fierro R. Effect of two insecticides and two herbicides on the porcine sperm motility patterns using computer-assisted semen analysis (CASA) in vitro. Reprod Toxicol 22 (2006) 508-512
23. Yang J., Zhang Y., Wang Y., and Cui S. Toxic effects of zearalenone and α-zearalenol on the regulation of steroidogenesis and testosterone production in mouse Leydig cells. Toxicol In Vitro 21 (2007) 558-565
24. Evenson D.P., and Melamed M.R. Rapid analysis of normal and abnormal cell types in human semen and testis biopsies by flow cytometry. J Histochem Cytochem 31 (1983) 248-253
25. Boe-Hansen G.B., Ersboll A.K., and Christensnen P. Variability and laboratory factors affecting the sperm chromatin structure assay in human semen. J Androl 26 3 (2005) 360-368
26. Evenson D.P., and Wixon R. Environmental toxicants cause sperm DNA fragmentation as detected by the sperm chromatin structure assay (SCSA). Toxicol Appl Pharmacol 207 (2005) S532-S537
27. Bochenek M., Smorag Z., and Pilch J. Sperm chromatin structure assay of bulls qualified for artificial insemination. Theriogenology 56 (2001) 557-567
28. Tsakmakidis I.A., Lymberopoulos A.G., Alexopoulos C., Boscos C.M., and Kyriakis S.C. In vitro effect of zearalenone and α-zearalenol in boar sperm characteristics and acrosome reaction. Reprod Dom Anim 41 (2006) 394-401
29. Rajkovic A., Uyttendaele M., and Debevere J. Computer aided boar semen motility analysis for cereulide detection in different food matrices. Int J Food Microbiol 114 (2007) 92-99
30. Muratori M., Piomboni P., Baldi E., Filimberti E., Pecchioli P., Moretti E., et al. Functional and ultrastructural features of DNA-fragmented human sperm. J Androl 21 (2000) 903-912
31. Giwercman A., Richtoff J., Hjollund H., Bonde J.P., Jepson K., Frohm B., et al. Correlation between sperm motility and sperm chromatin structure assay parameters. Fertil Steril 80 (2003) 1404-1412
32. Benchaib M., Lornage J., Mazoyer C., Lejeune H., Salle B., and Guerin J.F. Sperm deoxyribonucleic acid fragmentation as a prognostic indicator of assisted reproductive technology outcome. Fertil Steril 87 (2007) 93-100
33. Rago V., Aquila S., Panza R., and Carpino A. Cytochrome p450arom, androgen and estrogen receptors in pig sperm. Reprod Biol Endocrinol 5 (2007) 23 10.1186/1477-7827-5-23