Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU

Science Signaling

Volumn 8, Issue 366, 2015, Pages ra23-

  Shanmughapriya, Santhanam ^a,b   Rajan, Sudarsan ^a,b   Hoffman, Nicholas E ^a,b   Zhang, Xueqian ^b   Guo, Shuchi ^a,b   Kolesar, Jill E ^c   Hines, Kevin J ^a,b   Ragheb, Jonathan ^a,b   Jog, Neelakshi R ^b   Caricchio, Roberto ^b   Baba, Yoshihiro ^d   Zhou, Yandong ^e   Kaufman, Brett A ^c   Cheung, Joseph Y ^b   Kurosaki, Tomohiro ^d   Gill, Donald L ^e   Madesh, Muniswamy ^a,b  

^a TEMPLE UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE   (United States)

^d OSAKA UNIVERSITY   (Japan)

^e PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; CYCLIC ADENOSINE MONOPHOSPHATE RESPONSE ELEMENT BINDING PROTEIN; IMMUNOGLOBULIN M; LUCIFERASE; MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME; STROMAL INTERACTION MOLECULE 1; STROMAL INTERACTION MOLECULE 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; AVIAN PROTEIN; CALCIUM CHANNEL; CREB1 PROTEIN, MOUSE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOCHONDRIAL CALCIUM UNIPORTER; MITOCHONDRIAL PROTEIN; ORAI1 PROTEIN, MOUSE; STIM1 PROTEIN, MOUSE;

ARTICLE; B LYMPHOCYTE; BINDING SITE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL CULTURE; CELL DEATH; CELL FATE; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CYTOSOLIC FRACTION; DNA PROTEIN COMPLEX; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HELA CELL LINE; HUMAN; HUMAN CELL; LYMPHOCYTE; META ANALYSIS; MITOCHONDRIAL CALCIUM UNIPORTER GENE; MITOCHONDRIAL GENOME; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; CHICKEN; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; AVIAN PROTEINS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL LINE; CHICKENS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENDOPLASMIC RETICULUM; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; ORAI1 PROTEIN; STROMAL INTERACTION MOLECULE 1;

EID: 84924180724     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005673     Document Type: Article

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