-
1
-
-
33846705453
-
Nasopharyngeal carcinoma: Molecular biomarker discovery and progress
-
Cho WC (2007)Nasopharyngeal carcinoma: molecular biomarker discovery and progress. Mol Cancer 6: 1.
-
(2007)
Mol Cancer
, vol.6
, pp. 1
-
-
Cho, W.C.1
-
2
-
-
47549106723
-
Nasopharyngeal carcinoma - Review of the molecular mechanisms of tumorigenesis
-
DOI 10.1002/hed.20833
-
Chou J, Lin YC, Kim J, You L, Xu Z, et al. (2008) Nasopharyngeal carcinoma-review of the molecular mechanisms of tumorigenesis. Head Neck 30: 946-963. (Pubitemid 352008957)
-
(2008)
Head and Neck
, vol.30
, Issue.7
, pp. 946-963
-
-
Chou, J.1
Lin, Y.-C.2
Kim, J.3
You, L.4
Xu, Z.5
He, B.6
Jablons, D.M.7
-
3
-
-
78449250038
-
Current treatment options for recurrent nasopharyngeal cancer
-
1
-
Suárez C1, Rodrigo JP, Rinaldo A, Langendijk JA, Shaha AR, et al. (2010) Current treatment options for recurrent nasopharyngeal cancer. Eur Arch Otorhinolaryngol 267: 18118-18124.
-
(2010)
Eur Arch Otorhinolaryngol
, vol.267
, pp. 18118-18124
-
-
Suárez, C.1
Rodrigo, J.P.2
Rinaldo, A.3
Langendijk, J.A.4
Shaha, A.R.5
-
4
-
-
78649311707
-
From man to mouse and back again: Advances in defining tumor AKTivities in vivo
-
Restuccia DF, Hemmings BA (2010) From man to mouse and back again: advances in defining tumor AKTivities in vivo. Dis Model Mech 3: 705-720.
-
(2010)
Dis Model Mech
, vol.3
, pp. 705-720
-
-
Restuccia, D.F.1
Hemmings, B.A.2
-
5
-
-
33745260930
-
AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling
-
DOI 10.1158/0008-5472.CAN-06-0364
-
Riemenschneider MJ, Betensky RA, Pasedag SM, Louis DN (2006) AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling. Cancer Res 66: 5618-5623. (Pubitemid 43927113)
-
(2006)
Cancer Research
, vol.66
, Issue.11
, pp. 5618-5623
-
-
Riemenschneider, M.J.1
Betensky, R.A.2
Pasedag, S.M.3
Louis, D.N.4
-
6
-
-
59749101669
-
mTOR: Dissecting regulation and mechanism of action to understand human disease
-
Goberdhan DI, Boyd CA (2009) mTOR: dissecting regulation and mechanism of action to understand human disease. Biochem Soc Trans 37: 213.
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 213
-
-
Goberdhan, D.I.1
Boyd, C.A.2
-
7
-
-
4043171462
-
Upstream and downstream of mTOR
-
DOI 10.1101/gad.1212704
-
Hay N, Sonenberg N (2004) Upstream and downstream of mTOR. Genes Dev18: 1926-1945. (Pubitemid 39071573)
-
(2004)
Genes and Development
, vol.18
, Issue.16
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
8
-
-
84857675728
-
The mTOR signalling pathway in human cancer
-
Pópulo H, Lopes JM, Soares P (2012) The mTOR signalling pathway in human cancer. Int J Mol Sci13: 1886-1918.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 1886-1918
-
-
Pópulo, H.1
Lopes, J.M.2
Soares, P.3
-
9
-
-
2342639670
-
Signaling control of mRNA translation in cancer pathogenesis
-
DOI 10.1038/sj.onc.1207590
-
Holland EC, Sonenberg N, Pandolfi PP, Thomas G (2004) Signaling control of mRNA translation in cancer pathogenesis. Oncogene 23: 3138-3144. (Pubitemid 38638825)
-
(2004)
Oncogene
, vol.23
, Issue.18
, pp. 3138-3144
-
-
Holland, E.C.1
Sonenberg, N.2
Pandolfi, P.P.3
Thomas, G.4
-
10
-
-
18844429786
-
Molecularly targeted therapy for gastrointestinal cancer
-
DOI 10.2174/1568009053765771
-
Wiedmann MW, Caca K (2005) Molecularly targeted therapy for gastrointestinal cancer. Curr Cancer Drug Targets 5: 171-193. (Pubitemid 40694859)
-
(2005)
Current Cancer Drug Targets
, vol.5
, Issue.3
, pp. 171-193
-
-
Wiedmann, M.W.1
Caca, K.2
-
11
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
-
DOI 10.1038/nm0202-128
-
Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, et al. (2002) Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med 8: 128-135. (Pubitemid 34155123)
-
(2002)
Nature Medicine
, vol.8
, Issue.2
, pp. 128-135
-
-
Guba, M.1
Von Breitenbuch, P.2
Steinbauer, M.3
Koehl, G.4
Flegel, S.5
Hornung, M.6
Bruns, C.J.7
Zuelke, C.8
Farkas, S.9
Anthuber, M.10
Jauch, K.-W.11
Geissler, E.K.12
-
12
-
-
74949114784
-
Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer
-
Yoshizawa A, Fukuoka J, Shimizu S, Shilo K, Franks TJ, et al. (2010) Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer. Clin Cancer Res 16: 240-248.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 240-248
-
-
Yoshizawa, A.1
Fukuoka, J.2
Shimizu, S.3
Shilo, K.4
Franks, T.J.5
-
13
-
-
77952311165
-
Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer
-
Johnson SM, Gulhati P, Rampy BA, Han Y, Rychahou PG, et al. (2010) Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer. J Am Coll Surg 210: 767-776.
-
(2010)
J Am Coll Surg
, vol.210
, pp. 767-776
-
-
Johnson, S.M.1
Gulhati, P.2
Rampy, B.A.3
Han, Y.4
Rychahou, P.G.5
-
14
-
-
65949098918
-
Identification of potential driver genes in human liver carcinoma by genomewide screening
-
Woo HG, Park ES, Lee JS, Lee YH, Ishikawa T, et al. (2009) Identification of potential driver genes in human liver carcinoma by genomewide screening. Cancer Res 69: 4059-4066.
-
(2009)
Cancer Res
, vol.69
, pp. 4059-4066
-
-
Woo, H.G.1
Park, E.S.2
Lee, J.S.3
Lee, Y.H.4
Ishikawa, T.5
-
15
-
-
84883868478
-
Activation of the PI3K/AKT/mTOR pathway in diffuse large B cell lymphoma: Clinical significance and inhibitory effect of rituximab
-
Xu ZZ, Xia ZG, Wang AH, Wang WF, Liu ZY, et al. (2013) Activation of the PI3K/AKT/mTOR pathway in diffuse large B cell lymphoma: clinical significance and inhibitory effect of rituximab. Ann Hematol 92: 1351-1358.
-
(2013)
Ann Hematol
, vol.92
, pp. 1351-1358
-
-
Xu, Z.Z.1
Xia, Z.G.2
Wang, A.H.3
Wang, W.F.4
Liu, Z.Y.5
-
16
-
-
77954296394
-
4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors
-
She QB, Halilovic E, Ye Q, Zhen W, Shirasawa S, et al. (2010) 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors. Cancer Cell 18: 39-51.
-
(2010)
Cancer Cell
, vol.18
, pp. 39-51
-
-
She, Q.B.1
Halilovic, E.2
Ye, Q.3
Zhen, W.4
Shirasawa, S.5
-
17
-
-
24044551995
-
PI3K/Akt/mTOR pathway as a target for cancer therapy
-
DOI 10.1097/01.cad.0000173476.67239.3b
-
Morgensztern D, McLeod HL (2005) PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 16: 797-803. (Pubitemid 41215743)
-
(2005)
Anti-Cancer Drugs
, vol.16
, Issue.8
, pp. 797-803
-
-
Morgensztern, D.1
McLeod, H.L.2
-
18
-
-
82355160843
-
Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases
-
Adamo B, Deal AM, Burrows E, Geradts J, Hamilton E, et al. (2011) Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases. Breast Cancer Res 13: R125.
-
(2011)
Breast Cancer Res
, vol.13
-
-
Adamo, B.1
Deal, A.M.2
Burrows, E.3
Geradts, J.4
Hamilton, E.5
-
19
-
-
84861203432
-
Activation of Akt is associated with poor prognosis and chemotherapeutic resistance in pediatric B-precursor acute lymphoblastic leukemia
-
Morishita N, Tsukahara H, Chayama K, Ishida T, Washio K, et al. (2012) Activation of Akt is associated with poor prognosis and chemotherapeutic resistance in pediatric B-precursor acute lymphoblastic leukemia. Pediatr Blood Cancer 59: 83-89.
-
(2012)
Pediatr Blood Cancer
, vol.59
, pp. 83-89
-
-
Morishita, N.1
Tsukahara, H.2
Chayama, K.3
Ishida, T.4
Washio, K.5
-
20
-
-
73849152723
-
Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein
-
Abedini MR, Muller EJ, Bergeron R, Gray DA, Tsang BK (2010) Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein. Oncogene 29: 11-25.
-
(2010)
Oncogene
, vol.29
, pp. 11-25
-
-
Abedini, M.R.1
Muller, E.J.2
Bergeron, R.3
Gray, D.A.4
Tsang, B.K.5
-
21
-
-
70449515802
-
Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells
-
Li H, Kim J, Waldman T (2009) Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells. Radiat Oncol 4: 1-10.
-
(2009)
Radiat Oncol
, vol.4
, pp. 1-10
-
-
Li, H.1
Kim, J.2
Waldman, T.3
-
22
-
-
79955479303
-
Treatment for metastatic nasopharyngeal carcinoma
-
Bensouda Y, Kaikani W, Ahbeddou N, Rahhali R, Jabri M, et al. (2011)Treatment for metastatic nasopharyngeal carcinoma. Eur Ann Otorhinolaryngol Head Neck Dis 128: 79-85.
-
(2011)
Eur Ann Otorhinolaryngol Head Neck Dis
, vol.128
, pp. 79-85
-
-
Bensouda, Y.1
Kaikani, W.2
Ahbeddou, N.3
Rahhali, R.4
Jabri, M.5
-
23
-
-
9244228003
-
Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
-
DOI 10.1158/0008-5472.CAN-04-2677
-
Topisirovic I, Ruiz-Gutierrez M, Borden KL (2004) Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities. Cancer Res J 64: 8639-8642. (Pubitemid 39552077)
-
(2004)
Cancer Research
, vol.64
, Issue.23
, pp. 8639-8642
-
-
Topisirovic, I.1
Ruiz-Gutierrez, M.2
Borden, K.L.B.3
-
24
-
-
33846276209
-
4E-binding protein 1, a cell signaling hallmark in breast cancer that correlates with pathologic grade and prognosis
-
DOI 10.1158/1078-0432.CCR-06-1560
-
Rojo F, Najera L, Lirola J, Jiménez J, Guzmán M, et al. (2007) 4E-binding protein 1, a cell signaling hallmark in breast cancer that correlates with pathologic grade and prognosis. Clin Cancer Res 13: 81-89. (Pubitemid 46121856)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.1
, pp. 81-89
-
-
Rojo, F.1
Najera, L.2
Lirola, J.3
Jimenez, J.4
Guzman, M.5
Dolors, S.M.6
Baselga, J.7
Ramon Y, C.S.8
-
25
-
-
2442459672
-
Role of the p70S6K pathway in regulating the actin cytoskeleton and cell migration
-
DOI 10.1016/j.yexcr.2003.12.032, PII S001448270300689X
-
Berven LA, Willard FS, Crouch MF (2004) Role of the p70S6K pathway in regulating the actin cytoskeleton and cell migration. Exp Cell Res 296: 183-195. (Pubitemid 38624640)
-
(2004)
Experimental Cell Research
, vol.296
, Issue.2
, pp. 183-195
-
-
Berven, L.A.1
Willard, F.S.2
Crouch, M.F.3
-
26
-
-
74949110996
-
The role of mTOR and phosphop70S6K in pathogenesis and progression of gastric carcinomas: An immunohistochemical study on tissue microarray
-
Xiao L, Wang YC, Li WS, Du Y (2009) The role of mTOR and phosphop70S6K in pathogenesis and progression of gastric carcinomas: an immunohistochemical study on tissue microarray. J Exp Clin Cancer Res 28: 152.
-
(2009)
J Exp Clin Cancer Res
, vol.28
, pp. 152
-
-
Xiao, L.1
Wang, Y.C.2
Li, W.S.3
Du, Y.4
-
27
-
-
33750089285
-
Phosphorylated 4E binding protein 1: A hallmark of cell signaling that correlates with survival in ovarian cancer
-
DOI 10.1002/cncr.22195
-
Castellvi J, Garcia A, Rojo F, Ruiz-Marcellan C, Gil A, et al. (2006) Phosphorylated 4E binding protein 1: a hallmark of cell signaling that correlates with survival in ovarian cancer. Cancer 107: 1801-1811. (Pubitemid 44582949)
-
(2006)
Cancer
, vol.107
, Issue.8
, pp. 1801-1811
-
-
Castellvi, J.1
Garcia, A.2
Rojo, F.3
Ruiz-Marcellan, C.4
Gil, A.5
Baselga, J.6
Ramon Y, C.S.7
-
28
-
-
33746046387
-
Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma
-
DOI 10.1158/1078-0432.CCR-05-2202
-
Pelloski CE, Lin E, Zhang L, Yung WK, Colman H, et al. (2006) Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma. Clin Cancer Res 12: 3935-3941. (Pubitemid 44078078)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.13
, pp. 3935-3941
-
-
Pelloski, C.E.1
Lin, E.2
Zhang, L.3
Yung, W.K.A.4
Colman, H.5
Liu, J.-L.6
Woo, S.Y.7
Heimberger, A.B.8
Suki, D.9
Prados, M.10
Chang, S.11
Barker III, F.G.12
Fuller, G.N.13
Aldape, K.D.14
-
29
-
-
77952257255
-
Research Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma
-
Chen J, Hu CF, Hou JH, Shao Q, Yan LX, et al. (2010) Research Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma. J Transl Med 8: 30.
-
(2010)
J Transl Med
, vol.8
, pp. 30
-
-
Chen, J.1
Hu, C.F.2
Hou, J.H.3
Shao, Q.4
Yan, L.X.5
-
30
-
-
84882643175
-
XRCC3 and RAD51 Expression Are Associated with Clinical Factors in Breast Cancer
-
Hu J, Wang N, Wang YJ (2013) XRCC3 and RAD51 Expression Are Associated with Clinical Factors in Breast Cancer. PLoS One. 8: e72104.
-
(2013)
PLoS One
, vol.8
-
-
Hu, J.1
Wang, N.2
Wang, Y.J.3
|