XRCC3 and RAD51 Expression Are Associated with Clinical Factors in Breast Cancer

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Hu, Jia ^a,b   Wang, Ning ^b   Wang, Ya Jie ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; PROGESTERONE RECEPTOR; RAD51 PROTEIN; XRCC3 PROTEIN;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER STAGING; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DNA REPAIR; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MICROSCOPY; PREVALENCE; PROTEIN EXPRESSION; TISSUE MICROARRAY; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DNA-BINDING PROTEINS; FEMALE; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; RAD51 RECOMBINASE; RECEPTORS, PROGESTERONE;

EID: 84882643175     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072104     Document Type: Article

References (31)

1. Walsh T, King MC, (2007) Ten genes for inherited breast cancer. Cancer Cell 11(2): 103-5.
2. Ralhan R, Kaur J, Kreienberg R, Wiesmüller L, (2007) Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial cases. Cancer Lett 248(1): 1-17.
3. Bishop DK, Ear U, Bhattacharyya A, Calderone C, Beckett M, et al. (1998) Xrcc3 is required for assembly of Rad51 complexes in vivo. J Biol Chem 273(34): 21482-8.
4. Maacke H, Opitz S, Jost K, Hamdorf W, Henning W, et al. (2000) Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer. Int J Cancer 88(6): 907-13.
5. Barbano R, Copetti M, Perrone G, Pazienza V, Muscarella LA, et al. (2011) High RAD51 mRNA expression characterize estrogen receptor-positive/progesteron receptor-negative breast cancer and is associated with patient's outcome. Int J Cancer 129(3): 536-45.
6. He XF, Wei W, Su J, Yang ZX, Liu Y, et al. (2012) Association between the XRCC3 polymorphisms and breast cancer risk: meta-analysis based on case-control studies. Mol Biol Rep 39(5): 5125-34.
7. Qiu LX, Mao C, Yao L, Yu KD, Zhan P, et al. (2010) XRCC3 5′-UTR and IVS5-14 polymorphisms and breast cancer susceptibility: a meta-analysis. Breast Cancer Res Treat 122(2): 489-93.
8. Zhang B, Beeghly-Fadiel A, Long J, Zheng W, (2011) Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence. Lancet Oncol 12(5): 477-88.
9. Allred DC, Swanson PE, (2000) Testing for erbB-2 by immunohistochemistry in breast cancer. Am J Clin Pathol 113(2): 171-5.
10. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology™: breast cancer. Available at: http://www.nccn.org/professionals/physician_gls/pdf/breast.pdf. Accessed May 10, 2012.
11. Leake R, Barnes D, Pinder S, Ellis I, Anderson L, et al. (2000) Immunohistochemical detection of steroid receptors in breast cancer: a working protocol. UK Receptor Group, UK NEQAS, The Scottish Breast Cancer Pathology Group, and The Receptor and Biomarker Study Group of the EORTC. J Clin Pathol 53(8): 634-5.
12. Mohammed ZM, Edwards J, Orange C, Mallon E, Doughty JC, et al. (2012) Breast cancer outcomes by steroid hormone receptor status assessed visually and by computer image analysis. Histopathology 61(2): 283-92.
13. Cuatrecasas M, Santamaria G, Velasco M, Camacho E, Hernandez L, et al. (2006) ATM gene expression is associated with differentiation and angiogenesis in infiltrating breast carcinomas. Histol Histopathol 21(2): 149-56.
14. Angèle S, Treilleux I, Brémond A, Tanière P, Hall J, (2003) Altered expression of DNA double-strand break detection and repair proteins in breast carcinomas. Histopathology 43(4): 347-53.
15. Bartkova J, Tommiska J, Oplustilova L, Aaltonen K, Tamminen A, et al. (2008) Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene. Mol Oncol 2(4): 296-316.
16. Richardson C, Stark JM, Ommundsen M, Jasin M, (2004) Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability. Oncogene 23(2): 546-53.
17. Loignon M, Amrein L, Dunn M, Aloyz R, (2007) XRCC3 depletion induces spontaneous DNA breaks and p53-dependent cell death. Cell Cycle 6(5): 606-11.
18. Martinez-Marignac VL, Rodrigue A, Davidson D, Couillard M, Al-Moustafa AE, et al. (2011) The effect of a DNA repair gene on cellular invasiveness: XRCC3 over-expression in breast cancer cells. PLoS One 6(1): e16394.
19. Ang KK, Berkey BA, Tu X, Zhang HZ, Katz R, et al. (2002) Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 62(24): 7350-6.
20. Krause M, Zips D, Thames HD, Kummermehr J, Baumann M, (2006) Preclinical evaluation of molecular-targeted anticancer agents for radiotherapy. Radiother Oncol 80(2): 112-22.
21. Bergkvist GT, Argyle DJ, Pang LY, Muirhead R, Yool DA, (2011) Studies on the inhibition of feline EGFR in squamous cell carcinoma: enhancement of radiosensitivity and rescue of resistance to small molecule inhibitors. Cancer Biol Ther 11(11): 927-37.
22. Golding SE, Morgan RN, Adams BR, Hawkins AJ, Povirk LF, et al. (2009) Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells. Cancer Biol Ther 8(8): 730-8.
23. Kriegs M, Kasten-Pisula U, Rieckmann T, Holst K, Saker J, et al. (2010) The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining. DNA Repair (Amst) 9(8): 889-97.
24. Myllynen L, Rieckmann T, Dahm-Daphi J, Kasten-Pisula U, Petersen C, et al. (2011) In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status. Radiother Oncol 101(1): 147-51.
25. Toulany M, Minjgee M, Kehlbach R, Chen J, Baumann M, et al. (2010) ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway. Radiother Oncol 97(2): 338-45.
26. Liccardi G, Hartley JA, Hochhauser D, (2011) EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment. Cancer Res 71(3): 1103-14.
27. Murdoch WJ, (1998) Perturbation of sheep ovarian surface epithelial cells by ovulation: evidence for roles of progesterone and poly(ADP-ribose) polymerase in the restoration of DNA integrity. J Endocrinol 156(3): 503-8.
28. Martelli A, Mattioli F, Angiola M, Reimann R, Brambilla G, (2003) Species, sex and inter-individual differences in DNA repair induced by nine sex steroids in primary cultures of rat and human hepatocytes. Mutat Res 536(1-2): 69-78.
29. Leo JC, Wang SM, Guo CH, Aw SE, Zhao Y, et al. (2005) Gene regulation profile reveals consistent anticancer properties of progesterone in hormone-independent breast cancer cells transfected with progesterone receptor. Int J Cancer 117(4): 561-8.
30. Yanagisawa T, Urade M, Yamamoto Y, Furuyama J, (1998) Increased expression of human DNA repair genes, XRCC1, XRCC3 and RAD51, in radioresistant human KB carcinoma cell line N10. Oral Oncol 34(6): 524-822.
31. Wang ZM, Chen ZP, Xu ZY, Christodoulopoulos G, Bello V, et al. (2001) In vitro evidence for homologous recombinational repair in resistance to melphalan. J Natl Cancer Inst 93(19): 1473-8.