mTOR: Dissecting regulation and mechanism of action to understand human disease

Biochemical Society Transactions

Volumn 37, Issue 1, 2009, Pages 213-216

  Goberdhan, Deborah C I ^a   Boyd, C A Richard ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Amino acid sensing; Autophagy; Mammalian target of rapamycin (mTOR); Protein kinase; Therapeutic agent

Indexed keywords

AMINO ACID TRANSPORTER; GROWTH FACTOR RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAB7 PROTEIN; RAS PROTEIN; RHEB PROTEIN; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR FOXO; TUBERIN; AMINO ACID; PROTEIN KINASE; TRANSCRIPTION FACTOR;

ARTICLE; AUTOPHAGY; CELL GROWTH; CELL METABOLISM; CELL STRESS; CELL SURVIVAL; CHROMOSOME 10; CHROMOSOME DELETION; DEGENERATIVE DISEASE; ENDOSOME; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; NEOPLASM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; RNA TRANSLATION; SIGNAL TRANSDUCTION; UPREGULATION; ANTIBODY SPECIFICITY; GENERAL ASPECTS OF DISEASE; METABOLISM; REVIEW;

MAMMALIA;

AMINO ACIDS; DISEASE; HUMANS; ORGAN SPECIFICITY; PROTEIN KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 59749101669     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0370213     Document Type: Article

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