Stromal cell-derived CCL2 drives neuropathic pain states through myeloid cell infiltration in injured nerve

Brain, Behavior, and Immunity

Volumn 45, Issue , 2015, Pages 198-210

  Van Steenwinckel, Juliette ^a,b,c   Auvynet, Constance ^d,e,f   Sapienza, Anaïs ^d,g,h   Reaux Le Goazigo, Annabelle ^d,g,h   Combadière, Christophe ^d,e,f   Melik Parsadaniantz, Stéphane ^d,g,h  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c Fondation PremUP   (France)

^d SORBONNE UNIVERSITÉ   (France)

^e INSERM   (France)

^f Assistance publique Hôpitaux de Paris   (France)

^g INSTITUT DE LA VISION   (France)

^h CNRS   (France)

Author keywords

CCL2; Chemokine; FACS; Irradiated bone marrow chimeric mice; Macrophages; Neuropathic pain; Nociceptive behavior

Indexed keywords

CHEMOKINE RECEPTOR CCR2; MONOCYTE CHEMOTACTIC PROTEIN 1; N [2 [[1 [4 (1,3 BENZODIOXOL 5 YL) 4 HYDROXYCYCLOHEXYL] 4 ETHOXY 3 PYRROLIDINYL]AMINO] 2 OXOETHYL] 3 (TRIFLUOROMETHYL)BENZAMIDE; SYNAPTOPHYSIN; CCL2 PROTEIN, MOUSE; CCL2 PROTEIN, RAT;

ADULT; ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL INFILTRATION; CHIMERA; CHRONIC CONSTRICTION INJURY; CHRONIC PAIN; CONTROLLED STUDY; EXPERIMENTAL SCIATIC NERVE INJURY; GENE DELETION; IMMUNOCOMPETENT CELL; MACROPHAGE; MALE; MICROINJECTION; MONOCYTE; MONONUCLEAR PHAGOCYTE; MOUSE; NERVE FIBER; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NERVE; SIGNAL TRANSDUCTION; STROMA CELL; UPREGULATION; ANIMAL; GENETICS; HYPERALGESIA; IMMUNOLOGY; INJURIES; NEURALGIA; STENOSIS, OCCLUSION AND OBSTRUCTION;

ANIMALS; BONE MARROW TRANSPLANTATION; CHEMOKINE CCL2; CONSTRICTION, PATHOLOGIC; HYPERALGESIA; MACROPHAGES; MICE; MONOCYTES; MYELOID CELLS; NEURALGIA; PERIPHERAL NERVE INJURIES; RATS; SCIATIC NERVE; UP-REGULATION;

EID: 84924075147     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2014.10.016     Document Type: Article

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