CX3CL1-mediated macrophage activation contributed to paclitaxel-induced DRG neuronal apoptosis and painful peripheral neuropathy

Brain, Behavior, and Immunity

Volumn 40, Issue , 2014, Pages 155-165

  Huang, Zhen Zhen ^a   Li, Dai ^a   Liu, Cui Cui ^a   Cui, Yu ^a   Zhu, He Quan ^a   Zhang, Wen Wen ^a   Li, Yong Yong ^a   Xin, Wen Jun ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Allodynia; Apoptosis; CX3CL1; Macrophage; P38 MAPK; Paclitaxel

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE 3; CLODRONIC ACID; FRACTALKINE; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUTRALIZING ANTIBODY; PACLITAXEL; ANTINEOPLASTIC AGENT; CX3CL1 PROTEIN, RAT;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EVOKED RESPONSE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGE CULTURE; MACROPHAGE FUNCTION; MALE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVE FIBER; NERVOUS SYSTEM INFLAMMATION; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORY NERVE CELL; SPINAL CORD DORSAL HORN; SPINAL GANGLION; UPREGULATION; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; INJURIES; METABOLISM; NERVE CELL; PAIN; SCIATIC NERVE; SPRAGUE DAWLEY RAT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CHEMOKINE CX3CL1; GANGLIA, SPINAL; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; NEURONS; PACLITAXEL; PAIN; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; UP-REGULATION;

EID: 84904089879     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2014.03.014     Document Type: Article

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