The molecular link between C-C-chemokine ligand 2-induced leukocyte recruitment and hyperalgesia

Journal of Pain

Volumn 14, Issue 9, 2013, Pages 897-910

  Pflücke, Diana ^a   Hackel, Dagmar ^a,b   Mousa, Shaaban A ^b   Partheil, Anna ^a   Neumann, Annick ^a   Brack, Alexander ^a   Rittner, Heike L ^a  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

CCL2; cyclooxygenase 2; electrophysiology; macrophages; reactive oxygen species; transient receptor potential ankyrin 1; transient receptor potential vannilloid 1

Indexed keywords

4 HYDROXYNONENAL; ANKYRIN; ANKYRIN 1; CD68 ANTIGEN; CYCLOOXYGENASE 2; CYCLOPHOSPHAMIDE; HC 30031; MACROPHAGE DERIVED CHEMOKINE; N (4 TERT BUTYLPHENYL) 4 (3 CHLORO 2 PYRIDINYL) 1 PIPERAZINECARBOXAMIDE; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HYPERALGESIA; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; LEUKOPENIA; MACROPHAGE; MALE; MONOCYTE; NEUTROPHIL; NONHUMAN; PAIN THRESHOLD; PROTEIN FUNCTION; RAT;

CCL2; CYCLOOXYGENASE-2; ELECTROPHYSIOLOGY; MACROPHAGES; REACTIVE OXYGEN SPECIES; TRANSIENT RECEPTOR POTENTIAL ANKYRIN 1; TRANSIENT RECEPTOR POTENTIAL VANNILLOID 1;

ALDEHYDES; ANIMALS; CHEMOKINE CCL2; CIGUATOXINS; CYCLOPHOSPHAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; HOT TEMPERATURE; HUMANS; HYPERALGESIA; IMMUNOSUPPRESSIVE AGENTS; LEUKOCYTES; MACROPHAGES; MALE; PAIN THRESHOLD; PHYSICAL STIMULATION; PYRAZINES; PYRIDINES; RATS; RATS, WISTAR; REACTION TIME; REACTIVE OXYGEN SPECIES; RECEPTORS, CCR2; TIME FACTORS;

EID: 84883758135     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2013.02.012     Document Type: Article

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