SiRNA-Act1 inhibits the function of IL-17 on lung fibroblasts via the NF-κB pathway

Respiration

Volumn 86, Issue 4, 2013, Pages 332-340

  Dong, Zhaoxing ^a   Yang, Yanni ^b   Zhang, Tao ^a   Li, Yongxia ^a   Kang, Qinxin ^a   Lei, Wen ^a   Cao, Yu ^a   Niu, Xiaoqun ^a   Wang, Dianhua ^c   Tai, Wenlin ^c  

^a Glaxo Wellcome R and D   (United Kingdom)

^b Department of Ophthalmology ^*  (United Kingdom)

^c KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Activator 1; Interleukin 17; Lung fibroblast; Lung fibrosis

Indexed keywords

ACTIVATOR 1; ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; PROTEIN KINASE; RECOMBINANT CYTOKINE; RECOMBINANT INTERLEUKIN 17; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLEOMYCIN-INDUCED PULMONARY FIBROSIS; CELL CULTURE; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; GROWTH INHIBITION; LUNG FIBROBLAST; MALE; MOUSE; NONHUMAN; PRIMARY CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; CELL PROLIFERATION; CELL TRANSDIFFERENTIATION; COLLAGEN; FIBROBLASTS; GENE SILENCING; INTERLEUKIN-17; LUNG; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; REPLICATION PROTEIN C; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84888033963     PISSN: 00257931     EISSN: 14230356     Source Type: Journal    
DOI: 10.1159/000348403     Document Type: Article

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