Cigarette smoke exposure reveals a novel role for the MEK/ERK1/2 MAPK pathway in regulation of CFTR

Biochimica et Biophysica Acta - General Subjects

Volumn 1850, Issue 6, 2015, Pages 1224-1232

  Xu, Xiaohua ^a   Balsiger, Robert ^a   Tyrrell, Jean ^b   Boyaka, Prosper N ^a   Tarran, Robert ^b   Cormet Boyaka, Estelle ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Airway epithelial cell; CFTR; Cigarette smoke; MAPK pathway

Indexed keywords

ACETYLCYSTEINE; CIGARETTE SMOKE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; RNA; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; ANTIOXIDANT; CBL PROTEIN; CBL PROTEIN, HUMAN; CFTR PROTEIN, HUMAN; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN KINASE INHIBITOR; SMOKE;

ARTICLE; BIOTINYLATION; BRONCHIAL EPITHELIAL CELL; BRONCHUS MUCOSA; CELL MEMBRANE; CELL SURVIVAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; EPITHELIUM CELL; EXPOSURE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; ADVERSE EFFECTS; BRONCHUS; CELL LINE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMOKE; SMOKING; TIME;

ANTIOXIDANTS; BRONCHI; CELL LINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DOWN-REGULATION; EPITHELIAL CELLS; HUMANS; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-CBL; RNA INTERFERENCE; SMOKE; SMOKING; TIME FACTORS; TRANSFECTION;

EID: 84923902575     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2015.02.004     Document Type: Article

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