Loss of Cftr function exacerbates the phenotype of Na+ hyperabsorption in murine airways

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 7, 2013, Pages

  Livraghi Butrico, Alessandra ^a   Kelly, Elizabeth J ^a   Wilkinson, Kristen J ^a   Rogers, Troy D ^a   Gilmore, Rodney C ^a   Harkema, Jack R ^b   Randell, Scott H ^a   Boucher, Richard C ^a   O'Neal, Wanda K ^a   Grubb, Barbara R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

F508 CFTR; Airway epithelia necrosis; Airway Inflammation; Cystic fibrosis; ENaC; Genetically modified mice

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL SODIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL BETA SUBUNIT; CHLORIDE; SCNN1B PROTEIN, MOUSE; SODIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BACTERIAL LOAD; CELL DEATH; CLARA CELL; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; LUNG FIBROSIS; MOUSE; NEUTROPHIL CHEMOTAXIS; NEWBORN MORTALITY; NONHUMAN; PHENOTYPE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN FUNCTION; SODIUM ABSORPTION; SODIUM CURRENT; SURVIVAL; ABSORPTION; ANIMAL; GENETICS; HUMAN; ION TRANSPORT; LOEFFLER PNEUMONIA; LUNG; METABOLISM; NECROSIS; NEUTROPHIL; PATHOLOGY; TRANSGENIC MOUSE;

ABSORPTION; ANIMALS; CHLORIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL SODIUM CHANNELS; HUMANS; ION TRANSPORT; LUNG; MICE; MICE, TRANSGENIC; NECROSIS; NEUTROPHIL INFILTRATION; NEUTROPHILS; PNEUMONIA; PULMONARY EOSINOPHILIA; SODIUM;

MLCS; MLOWN;

EID: 84878234654     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00150.2012     Document Type: Article

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