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Volumn 8, Issue 11, 2013, Pages

Identification of unstable network modules reveals disease modules associated with the progression of alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; DATABASES, FACTUAL; DISEASE PROGRESSION; HUMANS; MIDDLE AGED; YOUNG ADULT;

EID: 84894217648     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076162     Document Type: Article
Times cited : (26)

References (58)
  • 1
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • doi:10.1007/BF00308809. PubMed: 1759558
    • Braak H, Braak E (1991) Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 82: 239-259. doi:10.1007/BF00308809. PubMed: 1759558.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 2
    • 61649089088 scopus 로고    scopus 로고
    • Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia
    • doi:10.1016/j.neurobiolaging.2007.07.021. PubMed: 17845826
    • Haroutunian V, Katsel P, Schmeidler J (2009) Transcriptional vulnerability of brain regions in Alzheimer's disease and dementia. Neurobiol Aging 30: 561-573. doi:10.1016/j.neurobiolaging.2007.07.021. PubMed: 17845826.
    • (2009) Neurobiol Aging , vol.30 , pp. 561-573
    • Haroutunian, V.1    Katsel, P.2    Schmeidler, J.3
  • 3
    • 55749105400 scopus 로고    scopus 로고
    • Gene expression changes in the course of normal brain aging are sexually dimorphic
    • doi:10.1073/pnas.0806883105. PubMed: 18832152
    • Berchtold NC, Cribbs DH, Coleman PD, Rogers J, Head E et al. (2008) Gene expression changes in the course of normal brain aging are sexually dimorphic. Proc Natl Acad Sci U-S-A 105: 15605-15610. doi:10.1073/pnas.0806883105. PubMed: 18832152.
    • (2008) Proc Natl Acad Sci U-S-A , vol.105 , pp. 15605-15610
    • Berchtold, N.C.1    Cribbs, D.H.2    Coleman, P.D.3    Rogers, J.4    Head, E.5
  • 4
    • 80054993342 scopus 로고    scopus 로고
    • Spatiotemporal transcriptome of the human brain
    • doi:10.1038/nature10523. PubMed: 22031440
    • Kang HJ, Kawasawa YI, Cheng F, Zhu Y, Xu X et al. (2011) Spatiotemporal transcriptome of the human brain. Nature 478: 483-489. doi:10.1038/nature10523. PubMed: 22031440.
    • (2011) Nature , vol.478 , pp. 483-489
    • Kang, H.J.1    Kawasawa, Y.I.2    Cheng, F.3    Zhu, Y.4    Xu, X.5
  • 5
    • 84859741480 scopus 로고    scopus 로고
    • Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers
    • PubMed: 22461973
    • Chen L, Liu R, Liu ZP, Li M, Aihara K (2012) Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers. Sci Rep 2: 342. PubMed: 22461973.
    • (2012) Sci Rep , vol.2 , pp. 342
    • Chen, L.1    Liu, R.2    Liu, Z.P.3    Li, M.4    Aihara, K.5
  • 6
    • 78650373804 scopus 로고    scopus 로고
    • Network medicine: A network-based approach to human disease
    • doi:10.1038/nrg2918. PubMed: 21164525
    • Barabási AL, Gulbahce N, Loscalzo J (2011) Network medicine: a network-based approach to human disease. Nat Rev Genet 12: 56-68. doi:10.1038/nrg2918. PubMed: 21164525.
    • (2011) Nat Rev Genet , vol.12 , pp. 56-68
    • Barabási, A.L.1    Gulbahce, N.2    Loscalzo, J.3
  • 7
    • 38949175007 scopus 로고    scopus 로고
    • A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging
    • DOI 10.1523/JNEUROSCI.4098-07.2008
    • Miller JA, Oldham MC, Geschwind DH (2008) A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging. J Neurosci 28: 1410-1420. doi:10.1523/JNEUROSCI.4098-07.2008. PubMed: 18256261. (Pubitemid 351231536)
    • (2008) Journal of Neuroscience , vol.28 , Issue.6 , pp. 1410-1420
    • Miller, J.A.1    Oldham, M.C.2    Geschwind, D.H.3
  • 8
    • 77957296042 scopus 로고    scopus 로고
    • Analysis of Alzheimer's disease severity across brain regions by topological analysis of gene co-expression networks
    • Ray M, Zhang W (2010) Analysis of Alzheimer's disease severity across brain regions by topological analysis of gene co-expression networks. BMC. Syst Biol 4: 136.
    • (2010) BMC. Syst Biol , vol.4 , pp. 136
    • Ray, M.1    Zhang, W.2
  • 9
    • 77956850355 scopus 로고    scopus 로고
    • Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brains
    • Suppl 2
    • Liu ZP, Wang Y, Zhang XS, Chen L (2010) Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brains. BMC. Syst Biol 4 Suppl 2: S11.
    • (2010) BMC. Syst Biol , vol.4
    • Liu, Z.P.1    Wang, Y.2    Zhang, X.S.3    Chen, L.4
  • 10
    • 0026847039 scopus 로고
    • Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans
    • doi:10.1037/0033-295X.99.2.195. PubMed: 1594723
    • Squire LR (1992) Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol Rev 99: 195-231. doi:10.1037/0033-295X. 99.2.195. PubMed: 1594723.
    • (1992) Psychol Rev , vol.99 , pp. 195-231
    • Squire, L.R.1
  • 11
    • 84856804006 scopus 로고    scopus 로고
    • Memory enhancement and deep-brain stimulation of the entorhinal area
    • doi:10.1056/NEJMoa1107212. PubMed: 22316444
    • Suthana N, Haneef Z, Stern J, Mukamel R, Behnke E et al. (2012) Memory enhancement and deep-brain stimulation of the entorhinal area. N Engl J Med 366: 502-510. doi:10.1056/NEJMoa1107212. PubMed: 22316444.
    • (2012) N Engl J Med , vol.366 , pp. 502-510
    • Suthana, N.1    Haneef, Z.2    Stern, J.3    Mukamel, R.4    Behnke, E.5
  • 13
    • 0024317904 scopus 로고
    • Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported
    • doi:10.1001/jama.1989.03430180093036. PubMed: 2810583
    • Evans DA, Funkenstein HH, Albert MS, Scherr PA, Cook NR et al. (1989) Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported. JAMA 262: 2551-2556. doi:10.1001/jama.1989. 03430180093036. PubMed: 2810583.
    • (1989) JAMA , vol.262 , pp. 2551-2556
    • Evans, D.A.1    Funkenstein, H.H.2    Albert, M.S.3    Scherr, P.A.4    Cook, N.R.5
  • 14
    • 0042023711 scopus 로고    scopus 로고
    • Alzheimer disease in the US population: Prevalence estimates using the 2000 census
    • DOI 10.1001/archneur.60.8.1119
    • Hebert LE, Scherr PA, Bienias JL, Bennett DA, Evans DA (2003) Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol 60: 1119-1122. doi:10.1001/archneur.60.8.1119. PubMed: 12925369. (Pubitemid 36975801)
    • (2003) Archives of Neurology , vol.60 , Issue.8 , pp. 1119-1122
    • Hebert, L.E.1    Scherr, P.A.2    Bienias, J.L.3    Bennett, D.A.4    Evans, D.A.5
  • 15
    • 0031695197 scopus 로고    scopus 로고
    • Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
    • Brookmeyer R, Gray S, Kawas C (1998) Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am J Public Health 88: 1337-1342. doi:10.2105/AJPH.88.9.1337. PubMed: 9736873. (Pubitemid 28402270)
    • (1998) American Journal of Public Health , vol.88 , Issue.9 , pp. 1337-1342
    • Brookmeyer, R.1    Gray, S.2    Kawas, C.3
  • 16
    • 33644873184 scopus 로고    scopus 로고
    • BioGRID: A general repository for interaction datasets
    • doi:10.1093/nar/gkj109. PubMed: 16381927
    • Stark C, Breitkreutz BJ, Reguly T, Boucher L, Breitkreutz A et al. (2006) BioGRID: a general repository for interaction datasets. Nucleic Acids Res 34: D535-D539. doi:10.1093/nar/gkj109. PubMed: 16381927.
    • (2006) Nucleic Acids Res , vol.34
    • Stark, C.1    Breitkreutz, B.J.2    Reguly, T.3    Boucher, L.4    Breitkreutz, A.5
  • 18
    • 0037007048 scopus 로고    scopus 로고
    • Largescale analysis of the human and mouse transcriptomes
    • doi:10.1073/pnas.012025199. PubMed: 11904358
    • Su AI, Cooke MP, Ching KA, Hakak Y, Walker JR et al. (2002) Largescale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U-S-A 99: 4465-4470. doi:10.1073/pnas.012025199. PubMed: 11904358.
    • (2002) Proc Natl Acad Sci U-S-A , vol.99 , pp. 4465-4470
    • Su, A.I.1    Cooke, M.P.2    Ching, K.A.3    Hakak, Y.4    Walker, J.R.5
  • 19
    • 64349094767 scopus 로고    scopus 로고
    • Tissue specificity and the human protein interaction network
    • PubMed: 19357639
    • Bossi A, Lehner B (2009) Tissue specificity and the human protein interaction network. Mol Syst Biol 5: 260. PubMed: 19357639.
    • (2009) Mol Syst Biol , vol.5 , pp. 260
    • Bossi, A.1    Lehner, B.2
  • 22
    • 71849108522 scopus 로고    scopus 로고
    • Community detection algorithms: A comparative analysis
    • doi:10.1103/PhysRevE.80.056117. PubMed: 20365053
    • Lancichinetti A, Fortunato S (2009) Community detection algorithms: a comparative analysis. Phys Rev E 80: 056117. doi:10.1103/PhysRevE.80.056117. PubMed: 20365053.
    • (2009) Phys Rev E , vol.80 , pp. 056117
    • Lancichinetti, A.1    Fortunato, S.2
  • 23
    • 33745012299 scopus 로고    scopus 로고
    • Modularity and community structure in networks
    • doi:10.1073/pnas.0601602103. PubMed: 16723398
    • Newman ME (2006) Modularity and community structure in networks. Proc Natl Acad Sci U-S-A 103: 8577-8582. doi:10.1073/pnas.0601602103. PubMed: 16723398.
    • (2006) Proc Natl Acad Sci U-S-A , vol.103 , pp. 8577-8582
    • Newman, M.E.1
  • 24
    • 41349115432 scopus 로고    scopus 로고
    • The DAVID Gene Functional Classification Tool: A novel biological module-centric algorithm to functionally analyze large gene lists
    • doi:10.1186/gb-2007-8-9-r183. PubMed: 17784955
    • Huang DW, Sherman BT, Tan Q, Collins JR, Alvord WG et al. (2007) The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biol 8: R183. doi:10.1186/gb-2007-8-9-r183. PubMed: 17784955.
    • (2007) Genome Biol , vol.8
    • Huang, D.W.1    Sherman, B.T.2    Tan, Q.3    Collins, J.R.4    Alvord, W.G.5
  • 25
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • PubMed: 19131956
    • Huang DW, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57. PubMed: 19131956.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 26
    • 1942439646 scopus 로고    scopus 로고
    • The highly conserved and multifunctional NuA4 HAT complex
    • DOI 10.1016/j.gde.2004.02.009, PII S0959437X04000310
    • Doyon Y, Côté J (2004) The highly conserved and multifunctional NuA4 HAT complex. Curr Opin Genet Dev 14: 147-154. doi:10.1016/j.gde.2004.02.009. PubMed: 15196461. (Pubitemid 38520142)
    • (2004) Current Opinion in Genetics and Development , vol.14 , Issue.2 , pp. 147-154
    • Doyon, Y.1    Cote, J.2
  • 27
    • 0034682736 scopus 로고    scopus 로고
    • Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis
    • doi:10.1016/S0092-8674(00)00051-9. PubMed: 10966108
    • Ikura T, Ogryzko VV, Grigoriev M, Groisman R, Wang J et al. (2000) Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102: 463-473. doi:10.1016/S0092-8674(00)00051-9. PubMed: 10966108.
    • (2000) Cell , vol.102 , pp. 463-473
    • Ikura, T.1    Ogryzko, V.V.2    Grigoriev, M.3    Groisman, R.4    Wang, J.5
  • 28
    • 66449130744 scopus 로고    scopus 로고
    • RVB1/RVB2: Running rings around molecular biology
    • doi:10.1016/j.molcel.2009.05.016. PubMed: 19524533
    • Jha S, Dutta A (2009) RVB1/RVB2: running rings around molecular biology. Mol Cell 34: 521-533. doi:10.1016/j.molcel.2009.05.016. PubMed: 19524533.
    • (2009) Mol Cell , vol.34 , pp. 521-533
    • Jha, S.1    Dutta, A.2
  • 30
    • 78649767505 scopus 로고    scopus 로고
    • Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease
    • doi:10.1016/j.pneurobio.2010.10.006. PubMed: 21056617
    • Salminen A, Ojala J, Kaarniranta K, Hiltunen M, Soininen H (2011) Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease. Prog Neurobiol 93: 99-110. doi:10.1016/j.pneurobio.2010.10.006. PubMed: 21056617.
    • (2011) Prog Neurobiol , vol.93 , pp. 99-110
    • Salminen, A.1    Ojala, J.2    Kaarniranta, K.3    Hiltunen, M.4    Soininen, H.5
  • 31
    • 79960889419 scopus 로고    scopus 로고
    • Normalization of gene expression using SYBR green qPCR: A case for paraoxonase 1 and 2 in Alzheimer's disease brains
    • doi:10.1016/j.jneumeth.2011.05.026. PubMed: 21672555
    • Leduc V, Legault V, Dea D, Poirier J (2011) Normalization of gene expression using SYBR green qPCR: a case for paraoxonase 1 and 2 in Alzheimer's disease brains. J Neurosci Methods 200: 14-19. doi:10.1016/j.jneumeth.2011.05. 026. PubMed: 21672555.
    • (2011) J Neurosci Methods , vol.200 , pp. 14-19
    • Leduc, V.1    Legault, V.2    Dea, D.3    Poirier, J.4
  • 32
    • 0242322038 scopus 로고    scopus 로고
    • Identification of New Subunits of the Multiprotein Mammalian TRRAP/TIP60-containing Histone Acetyltransferase Complex
    • DOI 10.1074/jbc.C300389200
    • Cai Y, Jin J, Tomomori-Sato C, Sato S, Sorokina I et al. (2003) Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. J Biol Chem 278: 42733-42736. doi:10.1074/jbc.C300389200. PubMed: 12963728. (Pubitemid 37345881)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.44 , pp. 42733-42736
    • Cai, Y.1    Jin, J.2    Tomomori-Sato, C.3    Sato, S.4    Sorokina, I.5    Parmely, T.J.6    Conaway, R.C.7    Conaway, J.W.8
  • 34
    • 67349147423 scopus 로고    scopus 로고
    • Chromatin remodelling beyond transcription: The INO80 and SWR1 complexes
    • doi:10.1038/nrm2693. PubMed: 19424290
    • Morrison AJ, Shen X (2009) Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes. Nat Rev Mol Cell Biol 10: 373-384. doi:10.1038/nrm2693. PubMed: 19424290.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 373-384
    • Morrison, A.J.1    Shen, X.2
  • 35
    • 84862777943 scopus 로고    scopus 로고
    • An epigenetic blockade of cognitive functions in the neurodegenerating brain
    • doi:10.1038/nature10849. PubMed: 22388814
    • Gräff J, Rei D, Guan JS, Wang WY, Seo J et al. (2012) An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature 483: 222-226. doi:10.1038/nature10849. PubMed: 22388814.
    • (2012) Nature , vol.483 , pp. 222-226
    • Gräff, J.1    Rei, D.2    Guan, J.S.3    Wang, W.Y.4    Seo, J.5
  • 38
    • 78650922822 scopus 로고    scopus 로고
    • A novel mutation in MED12 causes FG syndrome (Opitz-Kaveggia syndrome)
    • doi:10.1111/j.1399-0004.2010.01449.x. PubMed: 20507344
    • Rump P, Niessen RC, Verbruggen KT, Brouwer OF, de Raad M et al. (2011) A novel mutation in MED12 causes FG syndrome (Opitz-Kaveggia syndrome). Clin Genet 79: 183-188. doi:10.1111/j.1399-0004.2010.01449.x. PubMed: 20507344.
    • (2011) Clin Genet , vol.79 , pp. 183-188
    • Rump, P.1    Niessen, R.C.2    Verbruggen, K.T.3    Brouwer, O.F.4    De Raad, M.5
  • 39
    • 48349122949 scopus 로고    scopus 로고
    • Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation
    • doi:10.1016/j.molcel. 2008.05.023. PubMed: 18691967
    • Ding N, Zhou H, Esteve PO, Chin HG, Kim S et al. (2008) Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation. Mol Cell 31: 347-359. doi:10.1016/j.molcel. 2008.05.023. PubMed: 18691967.
    • (2008) Mol Cell , vol.31 , pp. 347-359
    • Ding, N.1    Zhou, H.2    Esteve, P.O.3    Chin, H.G.4    Kim, S.5
  • 40
    • 33751209807 scopus 로고    scopus 로고
    • A subunit of the mediator complex regulates vertebrate neuronal development
    • doi:10.1073/pnas.0605414103. PubMed: 17088561
    • Wang X, Yang N, Uno E, Roeder RG, Guo S (2006) A subunit of the mediator complex regulates vertebrate neuronal development. Proc Natl Acad Sci U-S-A 103: 17284-17289. doi:10.1073/pnas.0605414103. PubMed: 17088561.
    • (2006) Proc Natl Acad Sci U-S-A , vol.103 , pp. 17284-17289
    • Wang, X.1    Yang, N.2    Uno, E.3    Roeder, R.G.4    Guo, S.5
  • 41
    • 0034131044 scopus 로고    scopus 로고
    • Impaired proteasome function in Alzheimer's disease
    • DOI 10.1046/j.1471-4159.2000.0750436.x
    • Keller JN, Hanni KB, Markesbery WR (2000) Impaired proteasome function in Alzheimer's disease. J Neurochem 75: 436-439. PubMed: 10854289. (Pubitemid 30418211)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.1 , pp. 436-439
    • Keller, J.N.1    Hanni, K.B.2    Markesbery, W.R.3
  • 42
    • 0034730172 scopus 로고    scopus 로고
    • Inhibition of the ubiquitin-proteasome system in Alzheimer's disease
    • doi:10.1073/pnas.170173897. PubMed: 10944193
    • Lam YA, Pickart CM, Alban A, Landon M, Jamieson C et al. (2000) Inhibition of the ubiquitin-proteasome system in Alzheimer's disease. Proc Natl Acad Sci U-S-A 97: 9902-9906. doi:10.1073/pnas.170173897. PubMed: 10944193.
    • (2000) Proc Natl Acad Sci U-S-A , vol.97 , pp. 9902-9906
    • Lam, Y.A.1    Pickart, C.M.2    Alban, A.3    Landon, M.4    Jamieson, C.5
  • 43
    • 52049112825 scopus 로고    scopus 로고
    • Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex
    • doi:10.1016/j.molcel.2008.08.027. PubMed: 18922472
    • Yao T, Song L, Jin J, Cai Y, Takahashi H et al. (2008) Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Mol Cell 31: 909-917. doi:10.1016/j.molcel. 2008.08.027. PubMed: 18922472.
    • (2008) Mol Cell , vol.31 , pp. 909-917
    • Yao, T.1    Song, L.2    Jin, J.3    Cai, Y.4    Takahashi, H.5
  • 44
    • 84856970989 scopus 로고    scopus 로고
    • Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network
    • doi:10.1093/hmg/ddr539. PubMed: 22100762
    • Nakamura Y, Tagawa K, Oka T, Sasabe T, Ito H et al. (2012) Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network. Hum Mol Genet 21: 1099-1110. doi:10.1093/hmg/ddr539. PubMed: 22100762.
    • (2012) Hum Mol Genet , vol.21 , pp. 1099-1110
    • Nakamura, Y.1    Tagawa, K.2    Oka, T.3    Sasabe, T.4    Ito, H.5
  • 45
    • 65649112466 scopus 로고    scopus 로고
    • Functional and evolutionary insights into human brain development through global transcriptome analysis
    • doi:10.1016/j.neuron.2009.03.027. PubMed: 19477152
    • Johnson MB, Kawasawa YI, Mason CE, Krsnik Z, Coppola G et al. (2009) Functional and evolutionary insights into human brain development through global transcriptome analysis. Neuron 62: 494-509. doi:10.1016/j.neuron.2009.03.027. PubMed: 19477152.
    • (2009) Neuron , vol.62 , pp. 494-509
    • Johnson, M.B.1    Kawasawa, Y.I.2    Mason, C.E.3    Krsnik, Z.4    Coppola, G.5
  • 46
    • 84866518216 scopus 로고    scopus 로고
    • An anatomically comprehensive atlas of the adult human brain transcriptome
    • doi:10.1038/nature11405. PubMed: 22996553
    • Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, Shen EH, Ng L et al. (2012) An anatomically comprehensive atlas of the adult human brain transcriptome. Nature 489: 391-399. doi:10.1038/nature11405. PubMed: 22996553.
    • (2012) Nature , vol.489 , pp. 391-399
    • Hawrylycz, M.J.1    Lein, E.S.2    Guillozet-Bongaarts, A.L.3    Shen, E.H.4    Ng, L.5
  • 47
    • 79956322553 scopus 로고    scopus 로고
    • Global quantification of mammalian gene expression control
    • doi:10.1038/nature10098. PubMed: 21593866
    • Schwanhäusser B, Busse D, Li N, Dittmar G, Schuchhardt J et al. (2011) Global quantification of mammalian gene expression control. Nature 473: 337-342. doi:10.1038/nature10098. PubMed: 21593866.
    • (2011) Nature , vol.473 , pp. 337-342
    • Schwanhäusser, B.1    Busse, D.2    Li, N.3    Dittmar, G.4    Schuchhardt, J.5
  • 49
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the ageing human brain
    • DOI 10.1038/nature02661
    • Lu T, Pan Y, Kao SY, Li C, Kohane I et al. (2004) Gene regulation and DNA damage in the ageing human brain. Nature 429: 883-891. doi:10.1038/nature02661. PubMed: 15190254. (Pubitemid 38843301)
    • (2004) Nature , vol.429 , Issue.6994 , pp. 883-891
    • Lu, T.1    Pan, Y.2    Kao, S.-Y.3    Li, C.4    Kohane, I.5    Chan, J.6    Yankner, B.A.7
  • 53
    • 58149182724 scopus 로고    scopus 로고
    • NCBI GEO: Archive for high-throughput functional genomic data
    • doi:10.1093/nar/gkn764. PubMed: 18940857
    • Barrett T, Troup DB, Wilhite SE, Ledoux P, Rudnev D et al. (2009) NCBI GEO: archive for high-throughput functional genomic data. Nucleic Acids Res 37: D885-D890. doi:10.1093/nar/gkn764. PubMed: 18940857.
    • (2009) Nucleic Acids Res , vol.37
    • Barrett, T.1    Troup, D.B.2    Wilhite, S.E.3    Ledoux, P.4    Rudnev, D.5
  • 54
    • 56349094785 scopus 로고    scopus 로고
    • Fast unfolding of communities in large networks
    • doi:10.1088/1742-5468/2008/10/P10008
    • Blondel VD, Guillaume JL, Lambiotte R, Lefebvre E (2008) Fast unfolding of communities in large networks. J Stat Mech P10008. doi:10.1088/1742-5468/ 2008/10/P10008.
    • (2008) J Stat Mech , vol.P10008
    • Blondel, V.D.1    Guillaume, J.L.2    Lambiotte, R.3    Lefebvre, E.4
  • 55
    • 41349117788 scopus 로고    scopus 로고
    • Finding community structure in very large networks
    • doi:10.1103/PhysRevE.70.066111. PubMed: 15697438
    • Clauset A, Newman MEJ, Moore C (2004) Finding community structure in very large networks. Phys Rev E 70: 066111. doi:10.1103/PhysRevE.70.066111. PubMed: 15697438.
    • (2004) Phys Rev E , vol.70 , pp. 066111
    • Clauset, A.1    Newman, M.E.J.2    Moore, C.3
  • 56
    • 0036529479 scopus 로고    scopus 로고
    • An efficient algorithm for large-scale detection of protein families
    • Enright AJ, Van Dongen S, Ouzounis CA (2002) An efficient algorithm for large-scale detection of protein families. Nucleic Acids Res 30: 1575-1584. doi:10.1093/nar/30.7.1575. PubMed: 11917018. (Pubitemid 34679732)
    • (2002) Nucleic Acids Research , vol.30 , Issue.7 , pp. 1575-1584
    • Enright, A.J.1    Van Dongen, S.2    Ouzounis, C.A.3
  • 57
    • 34247223815 scopus 로고    scopus 로고
    • Quantifying social group evolution
    • DOI 10.1038/nature05670, PII NATURE05670
    • Palla G, Barabási AL, Vicsek T (2007) Quantifying social group evolution. Nature 446: 664-667. doi:10.1038/nature05670. PubMed: 17410175. (Pubitemid 46606882)
    • (2007) Nature , vol.446 , Issue.7136 , pp. 664-667
    • Palla, G.1    Barabasi, A.-L.2    Vicsek, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.