The number of PML nuclear bodies increases in early S phase by a fission mechanism

Journal of Cell Science

Volumn 119, Issue 6, 2006, Pages 1026-1033

  Dellaire, Graham ^a   Ching, Reagan W ^a   Dehghani, Hesam ^a,b   Ren, Ying ^a   Bazett Jones, David P ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b FERDOWSI UNIVERSITY OF MASHHAD   (Iran)

Author keywords

DNA synthesis; Electron spectroscopic imaging; Nuclear organisation; Particle tracking; PML nuclear body

Indexed keywords

DNA;

ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE S PHASE; CELL FUSION; CELL NUCLEUS INCLUSION BODY; CELL SHAPE; CELL STRUCTURE; CHROMATIN CONDENSATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA REPAIR; DNA SYNTHESIS; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; TRANSCRIPTION REGULATION;

CELL LINE, TUMOR; CHROMATIN; HUMANS; INTRANUCLEAR INCLUSION BODIES; NEOPLASM PROTEINS; NUCLEAR MATRIX; NUCLEAR PROTEINS; S PHASE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 33645731002     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02816     Document Type: Article

References (27)

1. Bernardi, R. and Pandolfi, P. P. (2003). Role of PML and the PML-nuclear body in the control of programmed cell death. Oncogene 22, 9048-9057.
2. Boisvert, F. M., Hendzel, M. J. and Bazett-Jones, D. P. (2000). Promyelocytic leukemia (PML) nuclear bodies are protein structures that do not accumulate RNA. J. Cell Biol. 148, 283-292.
3. Chang, K. S., Fan, Y. H., Andreeff, M., Liu, J. and Mu, Z. M. (1995). The PML gene encodes a phosphoprotein associated with the nuclear matrix. Blood 85, 3646-3653.
4. Ching, R. W., Dellaire, G., Eskiw, C. H. and Bazett-Jones, D. P. (2005). PML bodies: a meeting place for genomic loci? J. Cell Sci. 118, 847-854.
5. Chubb, J. R., Boyle, S., Perry, P. and Bickmore, W. A. (2002). Chromatin motion is constrained by association with nuclear compartments in human cells. Curr. Biol. 12, 439-445.
6. Dellaire, G. and Bazett-Jones, D. P. (2004). PML nuclear bodies: dynamic sensors of DNA damage and cellular stress. BioEssays 26, 963-977.
7. Dellaire, G., Nisman, R. and Bazett-Jones, D. P. (2004). Correlative light and electron spectroscopic imaging of chromatin in situ. Methods Enzymol. 375, 456-478.
8. Dellaire, G., Eskiw, C. H., Dehgani, H., Ching, R. W. and Bazett-Jones, D. P. (2006). Mitotic accumulations of PML protein contribute to the re-establishment of PML nuclear bodies in G1. J. Cell Sci. 119, 1034-1042.
9. Drouin, A., Schmitt, A., Masse, J. M., Cieutat, A. M., Fichelson, S. and Cramer, E. M. (2001). Identification of PML oncogenic domains (PODs) in human megakaryocytes. Exp. Cell Res. 271, 277-285.
10. Erlandsson, F., Linnman, C., Ekholm, S., Bengtsson, E. and Zetterberg, A. (2000). A detailed analysis of cyclin A accumulation at the G(1)/S border in normal and transformed cells. Exp. Cell Res. 259, 86-95.
11. Eskiw, C. H., Dellaire, G., Mymryk, J. S. and Bazett-Jones, D. P. (2003). Size, position and dynamic behavior of PML nuclear bodies following cell stress as a paradigm for supramolecular trafficking and assembly. J. Cell Sci. 116, 4455-4466.
12. Eskiw, C. H., Dellaire, G. and Bazett-Jones, D. P. (2004). Chromatin contributes to structural integrity of promyelocytic leukemia bodies through a SUMO-1-independent mechanism. J. Biol. Chem. 279, 9577-9585.
13. Everett, R. D. (2001). DNA viruses and viral proteins that interact with PML nuclear bodies. Oncogene 20, 7266-7273.
14. Everett, R. D. and Murray, J. (2005). ND10 components relocate to sites associated with herpes simplex virus type 1 nucleoprotein complexes during virus infection. J. Virol. 79, 5078-5089.
15. Everett, R. D., Sourvinos, G., Leiper, C., Clements, J. B. and Orr, A. (2004). Formation of nuclear foci of the herpes simplex virus type 1 regulatory protein ICP4 at early times of infection: localization, dynamics, recruitment of ICP27, and evidence for the de novo induction of ND10-like complexes. J. Virol. 78, 1903-1917.
16. Gorisch, S. M., Wachsmuth, M., Ittrich, C., Bacher, C. P., Rippe, K. and Lichter, P. (2004). Nuclear body movement is determined by chromatin accessibility and dynamics. Proc. Natl. Acad. Sci. USA 101, 13221-13226.
17. Koken, M. H., Linares-Cruz, G., Quignon, F., Viron, A., Chelbi-Alix, M. K., Sobczak-Thepot, J., Juhlin, L., Degos, L., Calvo, F. and de The, H. (1995). The PML growth-suppressor has an altered expression in human oncogenesis. Oncogene 10, 1315-1324.
18. Leonhardt, H, Rahn, H. P., Weinzierl, P., Sporbert, A., Cremer, T., Zink, D. and Cardoso, M. C. (2000). Dynamics of DNA replication factories in living cells. J. Cell Biol. 149, 271-280.
19. Melnick, A. and Licht, J. D. (1999). Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 93, 3167-3215.
20. Pichierri, P., Franchitto, A. and Rosselli, F. (2004). BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks. EMBO J. 23, 3154-3163.
21. Platani, M., Goldberg, I., Lamond, A. I. and Swedlow, J. R. (2002). Cajal body dynamics and association with chromatin are ATP-dependent. Nat. Cell Biol. 4, 502-508.
22. Terris, B., Baldin, V., Dubois, S., Degott, C., Flejou, J. F., Henin, D. and Dejean, A. (1995). PML nuclear bodies are general targets for inflammation and cell proliferation. Cancer Res. 55, 1590-1597.
23. Wang, J., Shiels, C., Sasieni, P., Wu, P. J., Islam, S. A., Freemont, P. S. and Sheer, D. (2004). Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions. J. Cell Biol. 164, 515-526.
24. Wang, X. W., Tseng, A., Ellis, N. A., Spillare, E. A., Linke, S. P., Robles, A. I., Seker, H., Yang, Q., Hu, P., Beresten, S. et al. (2001). Functional interaction of p53 and BLM DNA helicase in apoptosis. J. Biol. Chem. 276, 32948-32955.
25. Wiesmeijer, K., Molenaar, C., Bekeer, I. M., Tanke, H. J. and Dirks, R. W. (2002). Mobile foci of Sp100 do not contain PML: PML bodies are immobile but PML and Sp100 proteins are not. J. Struct. Biol. 140, 180-188.
26. Zhong, S., Hu, P., Ye, T. Z., Stan, R., Ellis, N. A. and Pandolfi, P. P. (1999). A role for PML and the nuclear body in genomic stability. Oncogene 18, 7941-7947.
27. Zhong, S., Muller, S., Ronchetti, S., Freemont, P. S., Dejean, A. and Pandolfi, P. P. (2000). Role of SUMO-1-modified PML in nuclear body formation. Blood 95, 2748-2752.