Functional variations modulating PRKCA expression and alternative splicing predispose to multiple sclerosis

Human Molecular Genetics

Volumn 23, Issue 25, 2014, Pages 6746-6761

  Paraboschi, Elvezia M ^a   Rimoldi, Valeria ^a   Soldà, Giulia ^a   Tabaglio, Tommaso ^a   Dall'Osso, Claudia ^a   Saba, Elena ^a   Vigliano, Marco ^b   Salviati, Alessandro ^c   Leone, Maurizio ^d,e   Benedetti, Maria D ^f   Fornasari, Diego ^a   Saarela, Janna ^g   De Jager, Philip L ^h,i,j   Patsopoulos, Nikolaos A ^h,i,j   D'Alfonso, Sandra ^e   Gemmati, Donato ^b   Duga, Stefano ^a   Asselta, Rosanna ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF VERONA   (Italy)

^d MAGGIORE DELLA CARITÀ HOSPITAL   (Italy)

^e UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^f UNIVERSITY HOSPITAL OF VERONA   (Italy)

^g UNIVERSITY OF HELSINKI   (Finland)

^h BRIGHAM AND WOMEN S HOSPITAL   (United States)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

^j BROAD INSTITUTE OF MIT AND HARVARD   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; PROTEIN KINASE C ALPHA; MESSENGER RNA; PRKCA PROTEIN, HUMAN;

ADULT; AGED; ALLELE; ALTERNATIVE RNA SPLICING; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; INTRON; ITALIAN (CITIZEN); MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; NONSENSE MEDIATED MRNA DECAY; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYADENYLATION; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TH17 CELL; CELL LINE; CHEMISTRY; CHROMOSOME 17; EXON; GENE LOCUS; GENETIC PREDISPOSITION; GENETICS; INDEL MUTATION; METABOLISM; PATHOLOGY; RNA STABILITY; SIGNAL TRANSDUCTION;

ALLELES; ALTERNATIVE SPLICING; CELL LINE; CHROMOSOMES, HUMAN, PAIR 17; EXONS; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDEL MUTATION; INTRONS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; PROMOTER REGIONS, GENETIC; PROTEIN KINASE C-ALPHA; RNA STABILITY; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84923800522     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu392     Document Type: Article

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