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Volumn 26, Issue 2, 2010, Pages 59-65

Tandem repeat polymorphisms: modulators of disease susceptibility and candidates for 'missing heritability'

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOLOGY; BRAIN DISEASE; DISEASE PREDISPOSITION; DNA SEQUENCE; EVOLUTION; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC POLYMORPHISM; HERITABILITY; HUMAN; MEIOSIS; MENTAL DISEASE; MITOSIS; PRIORITY JOURNAL; SIMPLE SEQUENCE REPEAT; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 75149154292     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tig.2009.11.008     Document Type: Article
Times cited : (120)

References (76)
  • 1
    • 45849092558 scopus 로고    scopus 로고
    • Simple sequence repeats: genetic modulators of brain function and behavior
    • Fondon III J.W., et al. Simple sequence repeats: genetic modulators of brain function and behavior. Trends Neurosci. 31 (2008) 328-334
    • (2008) Trends Neurosci. , vol.31 , pp. 328-334
    • Fondon III, J.W.1
  • 2
    • 46449113997 scopus 로고    scopus 로고
    • The biological effects of simple tandem repeats: lessons from the repeat expansion diseases
    • Usdin K. The biological effects of simple tandem repeats: lessons from the repeat expansion diseases. Genome Res. 18 (2008) 1011-1019
    • (2008) Genome Res. , vol.18 , pp. 1011-1019
    • Usdin, K.1
  • 3
    • 33646130830 scopus 로고    scopus 로고
    • Simple sequence repeats as advantageous mutators in evolution
    • Kashi Y., and King D.G. Simple sequence repeats as advantageous mutators in evolution. Trends Genet. 22 (2006) 253-259
    • (2006) Trends Genet. , vol.22 , pp. 253-259
    • Kashi, Y.1    King, D.G.2
  • 4
    • 0032401047 scopus 로고    scopus 로고
    • Fragile sites still breaking
    • Sutherland G.R., et al. Fragile sites still breaking. Trends Genet. 14 (1998) 501-516
    • (1998) Trends Genet. , vol.14 , pp. 501-516
    • Sutherland, G.R.1
  • 5
    • 34250208181 scopus 로고    scopus 로고
    • Dynamic mutations as digital genetic modulators of brain development, function and dysfunction
    • Nithianantharajah J., and Hannan A.J. Dynamic mutations as digital genetic modulators of brain development, function and dysfunction. BioEssays 29 (2007) 525-535
    • (2007) BioEssays , vol.29 , pp. 525-535
    • Nithianantharajah, J.1    Hannan, A.J.2
  • 6
    • 42949147652 scopus 로고    scopus 로고
    • Expanded clinical phenotype of women with the FMR1 premutation
    • Coffey S.M., et al. Expanded clinical phenotype of women with the FMR1 premutation. Am. J. Med. Genet. A 146A (2008) 1009-1016
    • (2008) Am. J. Med. Genet. A , vol.146 A , pp. 1009-1016
    • Coffey, S.M.1
  • 7
    • 67649218764 scopus 로고    scopus 로고
    • A review of fragile X premutation disorders: expanding the psychiatric perspective
    • Bourgeois J.A., et al. A review of fragile X premutation disorders: expanding the psychiatric perspective. J. Clin. Psychiatry 70 (2009) 852-862
    • (2009) J. Clin. Psychiatry , vol.70 , pp. 852-862
    • Bourgeois, J.A.1
  • 8
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 409 (2001) 860-921
    • (2001) Nature , vol.409 , pp. 860-921
    • International Human Genome Sequencing Consortium1
  • 9
    • 0031081111 scopus 로고    scopus 로고
    • Simple sequence repeats as a source of quantitative genetic variation
    • Kashi Y., et al. Simple sequence repeats as a source of quantitative genetic variation. Trends Genet. 13 (1997) 74-78
    • (1997) Trends Genet. , vol.13 , pp. 74-78
    • Kashi, Y.1
  • 10
    • 66349113764 scopus 로고    scopus 로고
    • Unstable tandem repeats in promoters confer transcriptional evolvability
    • Vinces M.D., et al. Unstable tandem repeats in promoters confer transcriptional evolvability. Science 324 (2009) 1213-1216
    • (2009) Science , vol.324 , pp. 1213-1216
    • Vinces, M.D.1
  • 11
    • 11144230088 scopus 로고    scopus 로고
    • Molecular origins of rapid and continuous morphological evolution
    • Fondon III J.W., and Garner H.R. Molecular origins of rapid and continuous morphological evolution. Proc. Natl Acad. Sci. U. S. A. 101 (2004) 18058-18063
    • (2004) Proc. Natl Acad. Sci. U. S. A. , vol.101 , pp. 18058-18063
    • Fondon III, J.W.1    Garner, H.R.2
  • 12
    • 20644472668 scopus 로고    scopus 로고
    • Microsatellite instability generates diversity in brain and sociobehavioral traits
    • Hammock E.A.D., and Young L.J. Microsatellite instability generates diversity in brain and sociobehavioral traits. Science 308 (2005) 1630-1634
    • (2005) Science , vol.308 , pp. 1630-1634
    • Hammock, E.A.D.1    Young, L.J.2
  • 13
    • 0030033685 scopus 로고    scopus 로고
    • Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking
    • Benjamin J., et al. Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nat. Genet. 12 (1996) 81-84
    • (1996) Nat. Genet. , vol.12 , pp. 81-84
    • Benjamin, J.1
  • 14
    • 13344275183 scopus 로고    scopus 로고
    • Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of novelty seeking
    • Ebstein R.P., et al. Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of novelty seeking. Nat. Genet. 12 (1996) 78-80
    • (1996) Nat. Genet. , vol.12 , pp. 78-80
    • Ebstein, R.P.1
  • 15
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • Lesch K.-P., et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274 (1996) 1527-1531
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.-P.1
  • 16
    • 0031963478 scopus 로고    scopus 로고
    • Polygenic inheritance and micro/minisatellites
    • Comings D.E., et al. Polygenic inheritance and micro/minisatellites. Mol. Psychiatry 3 (1998) 21-31
    • (1998) Mol. Psychiatry , vol.3 , pp. 21-31
    • Comings, D.E.1
  • 17
    • 21844447826 scopus 로고    scopus 로고
    • Association of the dopamine transporter (DAT1) 10/10-repeat genotype with ADHD symptoms and response inhibition in a general population sample
    • Cornish K.M., et al. Association of the dopamine transporter (DAT1) 10/10-repeat genotype with ADHD symptoms and response inhibition in a general population sample. Mol. Psychiatry 10 (2005) 686-698
    • (2005) Mol. Psychiatry , vol.10 , pp. 686-698
    • Cornish, K.M.1
  • 18
    • 34548306781 scopus 로고    scopus 로고
    • A deletion variant of the α2b-adrenoceptor is related to emotional memory in Europeans and Africans
    • de Quervain D.J.-F., et al. A deletion variant of the α2b-adrenoceptor is related to emotional memory in Europeans and Africans. Nat. Neurosci. 10 (2007) 1137-1139
    • (2007) Nat. Neurosci. , vol.10 , pp. 1137-1139
    • de Quervain, D.J.-F.1
  • 19
    • 34548319358 scopus 로고    scopus 로고
    • Association analysis of 15 polymorphisms within 10 candidate genes for antisocial behavioural traits
    • Prichard Z.M., et al. Association analysis of 15 polymorphisms within 10 candidate genes for antisocial behavioural traits. Psychiatr. Genet. 17 (2007) 299-303
    • (2007) Psychiatr. Genet. , vol.17 , pp. 299-303
    • Prichard, Z.M.1
  • 20
    • 36049008356 scopus 로고    scopus 로고
    • AVPR1A and OXTR polymorphisms are associated with sexual and reproductive behavioral phenotypes in humans. Mutation in brief no. 981. Online
    • Prichard Z.M., et al. AVPR1A and OXTR polymorphisms are associated with sexual and reproductive behavioral phenotypes in humans. Mutation in brief no. 981. Online. Hum. Mutat. 28 (2007) 1150
    • (2007) Hum. Mutat. , vol.28 , pp. 1150
    • Prichard, Z.M.1
  • 21
    • 56949108250 scopus 로고    scopus 로고
    • Embryonic nervous system genes predominate in searches for dinucleotide simple sequence repeats flanked by conserved sequences
    • Riley D.E., and Krieger J.N. Embryonic nervous system genes predominate in searches for dinucleotide simple sequence repeats flanked by conserved sequences. Gene 429 (2009) 74-79
    • (2009) Gene , vol.429 , pp. 74-79
    • Riley, D.E.1    Krieger, J.N.2
  • 22
    • 37349020265 scopus 로고    scopus 로고
    • Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: meta-analysis and new data
    • Munafò M.R., et al. Association of the dopamine D4 receptor (DRD4) gene and approach-related personality traits: meta-analysis and new data. Biol. Psychiatry 63 (2008) 197-206
    • (2008) Biol. Psychiatry , vol.63 , pp. 197-206
    • Munafò, M.R.1
  • 23
    • 61449207211 scopus 로고    scopus 로고
    • 5-HTTLPR genotype and anxiety-related personality traits: a meta-analysis and new data
    • Munafò M.R., et al. 5-HTTLPR genotype and anxiety-related personality traits: a meta-analysis and new data. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (2009) 271-281
    • (2009) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.150 B , pp. 271-281
    • Munafò, M.R.1
  • 24
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio T.A., et al. Finding the missing heritability of complex diseases. Nature 461 (2009) 747-753
    • (2009) Nature , vol.461 , pp. 747-753
    • Manolio, T.A.1
  • 25
    • 52449094233 scopus 로고    scopus 로고
    • Short tandem repeats in human exons: a target for disease mutations
    • Madsen B.E., et al. Short tandem repeats in human exons: a target for disease mutations. BMC Genomics 9 (2008) 410
    • (2008) BMC Genomics , vol.9 , pp. 410
    • Madsen, B.E.1
  • 26
    • 53549094135 scopus 로고    scopus 로고
    • Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties
    • Bacolla A., et al. Abundance and length of simple repeats in vertebrate genomes are determined by their structural properties. Genome Res. 18 (2008) 1545-1553
    • (2008) Genome Res. , vol.18 , pp. 1545-1553
    • Bacolla, A.1
  • 27
    • 0029939169 scopus 로고    scopus 로고
    • Polymorphism in serotonin transporter gene associated with susceptibility to major depression
    • Ogilvie A.D., et al. Polymorphism in serotonin transporter gene associated with susceptibility to major depression. Lancet 347 (1996) 731-733
    • (1996) Lancet , vol.347 , pp. 731-733
    • Ogilvie, A.D.1
  • 28
    • 0034606330 scopus 로고    scopus 로고
    • Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder
    • Schulze T.G., et al. Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder. Am. J. Med. Genet. 96 (2000) 801-803
    • (2000) Am. J. Med. Genet. , vol.96 , pp. 801-803
    • Schulze, T.G.1
  • 29
    • 34548687990 scopus 로고    scopus 로고
    • Monoamine metabolites level in CSF is related to the 5-HTT gene polymorphism in treatment-resistant depression
    • Kishida I., et al. Monoamine metabolites level in CSF is related to the 5-HTT gene polymorphism in treatment-resistant depression. Neuropsychopharmacology 32 (2007) 2143-2151
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2143-2151
    • Kishida, I.1
  • 30
    • 68049126142 scopus 로고    scopus 로고
    • Accurate, large-scale genotyping of 5HTTLPR and flanking single nucleotide polymorphisms in an association study of depression, anxiety, and personality measures
    • Wray N.R., et al. Accurate, large-scale genotyping of 5HTTLPR and flanking single nucleotide polymorphisms in an association study of depression, anxiety, and personality measures. Biol. Psychiatry 66 (2009) 468-476
    • (2009) Biol. Psychiatry , vol.66 , pp. 468-476
    • Wray, N.R.1
  • 31
    • 0031229750 scopus 로고    scopus 로고
    • Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT)
    • Rees M., et al. Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT). Mol. Psychiatry 2 (1997) 398-402
    • (1997) Mol. Psychiatry , vol.2 , pp. 398-402
    • Rees, M.1
  • 32
    • 0036724341 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study
    • Neves-Pereira M., et al. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am. J. Hum. Genet. 71 (2002) 651-655
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 651-655
    • Neves-Pereira, M.1
  • 33
    • 12944312689 scopus 로고    scopus 로고
    • Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders
    • Lasky-Su J.A., et al. Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders. Am. J. Med. Genet. B Neuropsychiatr. Genet. 133B (2005) 110-115
    • (2005) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.133 B , pp. 110-115
    • Lasky-Su, J.A.1
  • 34
    • 53049106720 scopus 로고    scopus 로고
    • A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder
    • Benedetti F., et al. A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder. Neurosci. Lett. 445 (2008) 184-187
    • (2008) Neurosci. Lett. , vol.445 , pp. 184-187
    • Benedetti, F.1
  • 35
    • 0033808601 scopus 로고    scopus 로고
    • Brain derived neurotrophic factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia
    • Krebs M.O., et al. Brain derived neurotrophic factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia. Mol. Psychiatry 5 (2000) 558-562
    • (2000) Mol. Psychiatry , vol.5 , pp. 558-562
    • Krebs, M.O.1
  • 36
    • 33644611155 scopus 로고    scopus 로고
    • A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function
    • Reif A., et al. A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function. Mol. Psychiatry 11 (2006) 286-300
    • (2006) Mol. Psychiatry , vol.11 , pp. 286-300
    • Reif, A.1
  • 37
    • 33751191400 scopus 로고    scopus 로고
    • Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects
    • Passos Gregorio S., et al. Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects. Schizophr. Res. 88 (2006) 275-282
    • (2006) Schizophr. Res. , vol.88 , pp. 275-282
    • Passos Gregorio, S.1
  • 38
    • 33846383832 scopus 로고    scopus 로고
    • Positive association of schizophrenia to JARID2 gene
    • Pedrosa E., et al. Positive association of schizophrenia to JARID2 gene. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B (2007) 45-51
    • (2007) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.144 B , pp. 45-51
    • Pedrosa, E.1
  • 39
    • 36749104268 scopus 로고    scopus 로고
    • Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence
    • Gysin R., et al. Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence. Proc. Natl Acad. Sci. U. S. A. 104 (2007) 16621-16626
    • (2007) Proc. Natl Acad. Sci. U. S. A. , vol.104 , pp. 16621-16626
    • Gysin, R.1
  • 40
    • 67149112115 scopus 로고    scopus 로고
    • TATA box-binding protein gene is associated with risk for schizophrenia, age at onset and prefrontal function
    • Ohi K., et al. TATA box-binding protein gene is associated with risk for schizophrenia, age at onset and prefrontal function. Genes Brain Behav. 8 (2009) 473-480
    • (2009) Genes Brain Behav. , vol.8 , pp. 473-480
    • Ohi, K.1
  • 41
    • 57349143930 scopus 로고    scopus 로고
    • Association of the dopamine transporter (SLC6A3/DAT1) gene 9-6 haplotype with adult ADHD
    • Franke B., et al. Association of the dopamine transporter (SLC6A3/DAT1) gene 9-6 haplotype with adult ADHD. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (2008) 1576-1579
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.147 B , pp. 1576-1579
    • Franke, B.1
  • 42
    • 51449092787 scopus 로고    scopus 로고
    • Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls
    • Johnson K.A., et al. Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (2008) 927-937
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.147 B , pp. 927-937
    • Johnson, K.A.1
  • 43
    • 0345268657 scopus 로고    scopus 로고
    • Association of the androgen receptor CAG repeat polymorphism with Alzheimer's disease in men
    • Lehmann D.J., et al. Association of the androgen receptor CAG repeat polymorphism with Alzheimer's disease in men. Neurosci. Lett. 340 (2003) 87-90
    • (2003) Neurosci. Lett. , vol.340 , pp. 87-90
    • Lehmann, D.J.1
  • 44
    • 34547633480 scopus 로고    scopus 로고
    • Differential enrichment of simple sequence repeats in selected Alzheimer-associated genes
    • Hill D., et al. Differential enrichment of simple sequence repeats in selected Alzheimer-associated genes. Cell Mol. Biol. (Noisy-le-grand) 53 (2007) 23-31
    • (2007) Cell Mol. Biol. (Noisy-le-grand) , vol.53 , pp. 23-31
    • Hill, D.1
  • 45
    • 34548149724 scopus 로고    scopus 로고
    • Role of serotonin transporter polymorphisms in the behavioural and psychological symptoms in probable Alzheimer disease patients
    • Pritchard A.L., et al. Role of serotonin transporter polymorphisms in the behavioural and psychological symptoms in probable Alzheimer disease patients. Dement. Geriatr. Cogn. Disord. 24 (2007) 201-206
    • (2007) Dement. Geriatr. Cogn. Disord. , vol.24 , pp. 201-206
    • Pritchard, A.L.1
  • 46
    • 36549013598 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism and BPSD in mild Alzheimer's disease
    • Ueki A., et al. Serotonin transporter gene polymorphism and BPSD in mild Alzheimer's disease. J. Alzheimers Dis. 12 (2007) 245-253
    • (2007) J. Alzheimers Dis. , vol.12 , pp. 245-253
    • Ueki, A.1
  • 47
    • 47049110342 scopus 로고    scopus 로고
    • Association of a NOS1 promoter repeat with Alzheimer's disease
    • Galimberti D., et al. Association of a NOS1 promoter repeat with Alzheimer's disease. Neurobiol. Aging 29 (2008) 1359-1365
    • (2008) Neurobiol. Aging , vol.29 , pp. 1359-1365
    • Galimberti, D.1
  • 48
    • 47849086388 scopus 로고    scopus 로고
    • The androgen receptor's CAG/glutamine tract in mouse models of neurological disease and cancer
    • Lieberman A.P., and Robins D.M. The androgen receptor's CAG/glutamine tract in mouse models of neurological disease and cancer. J. Alzheimers Dis. 14 (2008) 247-255
    • (2008) J. Alzheimers Dis. , vol.14 , pp. 247-255
    • Lieberman, A.P.1    Robins, D.M.2
  • 49
    • 34548100282 scopus 로고    scopus 로고
    • The BC genotype of the VNTR polymorphism of platelet glycoprotein Ibalpha is overrepresented in patients with recurrent stroke regardless of aspirin therapy
    • Cervera A., et al. The BC genotype of the VNTR polymorphism of platelet glycoprotein Ibalpha is overrepresented in patients with recurrent stroke regardless of aspirin therapy. Cerebrovasc. Dis. 24 (2007) 242-246
    • (2007) Cerebrovasc. Dis. , vol.24 , pp. 242-246
    • Cervera, A.1
  • 50
    • 34247891781 scopus 로고    scopus 로고
    • IL1RN VNTR polymorphism in ischemic stroke: analysis in 3 populations
    • SWISS, ISGS, and MSGD Investigators
    • Worrall B.B., et al., SWISS, ISGS, and MSGD Investigators. IL1RN VNTR polymorphism in ischemic stroke: analysis in 3 populations. Stroke 38 (2007) 1189-1196
    • (2007) Stroke , vol.38 , pp. 1189-1196
    • Worrall, B.B.1
  • 51
    • 0037335985 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist gene polymorphisms in carotid atherosclerosis
    • Worrall B.B., et al. Interleukin-1 receptor antagonist gene polymorphisms in carotid atherosclerosis. Stroke 34 (2003) 790-793
    • (2003) Stroke , vol.34 , pp. 790-793
    • Worrall, B.B.1
  • 52
    • 53749088453 scopus 로고    scopus 로고
    • Pentanucleotide repeat polymorphism, lipoprotein(a) levels, and risk of ischemic heart disease
    • Kamstrup P.R., et al. Pentanucleotide repeat polymorphism, lipoprotein(a) levels, and risk of ischemic heart disease. J. Clin. Endocrinol. Metab. 93 (2008) 3769-3776
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 3769-3776
    • Kamstrup, P.R.1
  • 53
    • 34249988179 scopus 로고    scopus 로고
    • Trinucleotide repeats of programmed cell death-1 gene are associated with susceptibility to type 1 diabetes mellitus
    • Hiromine Y., et al. Trinucleotide repeats of programmed cell death-1 gene are associated with susceptibility to type 1 diabetes mellitus. Metabolism 56 (2007) 905-909
    • (2007) Metabolism , vol.56 , pp. 905-909
    • Hiromine, Y.1
  • 54
    • 43449095982 scopus 로고    scopus 로고
    • Intron 4 a/b polymorphism of the endothelial nitric oxide synthase gene is associated with both type 1 and type 2 diabetes in a genetically homogeneous population
    • Galanakis E., et al. Intron 4 a/b polymorphism of the endothelial nitric oxide synthase gene is associated with both type 1 and type 2 diabetes in a genetically homogeneous population. Hum. Immunol. 69 (2008) 279-283
    • (2008) Hum. Immunol. , vol.69 , pp. 279-283
    • Galanakis, E.1
  • 55
    • 16944365288 scopus 로고    scopus 로고
    • Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC
    • Laken S.J., et al. Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC. Nat. Genet. 17 (1997) 79-83
    • (1997) Nat. Genet. , vol.17 , pp. 79-83
    • Laken, S.J.1
  • 56
    • 38849178040 scopus 로고    scopus 로고
    • Prostate cancer risk and ESR1 TA, ESR2 CA repeat polymorphisms
    • McIntyre M.H., et al. Prostate cancer risk and ESR1 TA, ESR2 CA repeat polymorphisms. Cancer Epidemiol. Biomarkers Prev. 16 (2007) 2233-2236
    • (2007) Cancer Epidemiol. Biomarkers Prev. , vol.16 , pp. 2233-2236
    • McIntyre, M.H.1
  • 57
    • 34147186189 scopus 로고    scopus 로고
    • Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer
    • Schildkraut J.M., et al. Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer. Cancer Epidemiol. Biomarkers Prev. 16 (2007) 473-480
    • (2007) Cancer Epidemiol. Biomarkers Prev. , vol.16 , pp. 473-480
    • Schildkraut, J.M.1
  • 58
    • 37449023721 scopus 로고    scopus 로고
    • Trinucleotide repeats are prevalent among cancer-related genes
    • Haberman Y., et al. Trinucleotide repeats are prevalent among cancer-related genes. Trends Genet. 24 (2008) 14-18
    • (2008) Trends Genet. , vol.24 , pp. 14-18
    • Haberman, Y.1
  • 59
    • 25144494777 scopus 로고    scopus 로고
    • Intragenic tandem repeats generate functional variability
    • Verstrepen K.J., et al. Intragenic tandem repeats generate functional variability. Nat. Genet. 37 (2005) 986-990
    • (2005) Nat. Genet. , vol.37 , pp. 986-990
    • Verstrepen, K.J.1
  • 60
    • 17844383699 scopus 로고    scopus 로고
    • Functional insights from the distribution and role of homopeptide repeat-containing proteins
    • Faux N.G., et al. Functional insights from the distribution and role of homopeptide repeat-containing proteins. Genome Res. 15 (2005) 537-551
    • (2005) Genome Res. , vol.15 , pp. 537-551
    • Faux, N.G.1
  • 61
    • 0035853756 scopus 로고    scopus 로고
    • Novel frameshift mutations near short simple repeats
    • van Den Hurk W.H., et al. Novel frameshift mutations near short simple repeats. J Biol. Chem. 276 (2001) 11496-11498
    • (2001) J Biol. Chem. , vol.276 , pp. 11496-11498
    • van Den Hurk, W.H.1
  • 62
    • 33847077134 scopus 로고    scopus 로고
    • Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets
    • Krol J., et al. Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets. Mol. Cell 25 (2007) 575-586
    • (2007) Mol. Cell , vol.25 , pp. 575-586
    • Krol, J.1
  • 63
    • 59849088220 scopus 로고    scopus 로고
    • RNA regulation of epigenetic processes
    • Mattick J.S., et al. RNA regulation of epigenetic processes. BioEssays 31 (2009) 51-59
    • (2009) BioEssays , vol.31 , pp. 51-59
    • Mattick, J.S.1
  • 64
    • 67649983121 scopus 로고    scopus 로고
    • Instability and chromatin structure of expanded trinucleotide repeats
    • Dion V., and Wilson J.H. Instability and chromatin structure of expanded trinucleotide repeats. Trends Genet. 25 (2009) 288-297
    • (2009) Trends Genet. , vol.25 , pp. 288-297
    • Dion, V.1    Wilson, J.H.2
  • 65
    • 42149156593 scopus 로고    scopus 로고
    • DNA instability in postmitotic neurons
    • Gonitel R., et al. DNA instability in postmitotic neurons. Proc. Natl Acad. Sci. U. S. A. 105 (2008) 3467
    • (2008) Proc. Natl Acad. Sci. U. S. A. , vol.105 , pp. 3467
    • Gonitel, R.1
  • 66
    • 60549083544 scopus 로고    scopus 로고
    • An open access database of genome-wide association results
    • Johnson A.D., and O'Donnell C.J. An open access database of genome-wide association results. BMC Med. Genet. 10 (2009) 6
    • (2009) BMC Med. Genet. , vol.10 , pp. 6
    • Johnson, A.D.1    O'Donnell, C.J.2
  • 67
    • 0036255811 scopus 로고    scopus 로고
    • Candidate-gene approaches for studying complex genetic traits: practical considerations
    • Tabor H.K., et al. Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat. Rev. Genet. 3 (2002) 391-397
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 391-397
    • Tabor, H.K.1
  • 68
    • 42949131582 scopus 로고    scopus 로고
    • Marked variation in predicted and observed variability of tandem repeat loci across the human genome
    • O'Dushlaine C.T., and Shields D.C. Marked variation in predicted and observed variability of tandem repeat loci across the human genome. BMC Genomics 9 (2008) 175
    • (2008) BMC Genomics , vol.9 , pp. 175
    • O'Dushlaine, C.T.1    Shields, D.C.2
  • 69
    • 70350125551 scopus 로고    scopus 로고
    • Triplet repeat length bias and variation in the human transcriptome
    • Molla M., et al. Triplet repeat length bias and variation in the human transcriptome. Proc. Natl Acad. Sci. U. S. A. 106 (2009) 17095-17100
    • (2009) Proc. Natl Acad. Sci. U. S. A. , vol.106 , pp. 17095-17100
    • Molla, M.1
  • 70
    • 0037268258 scopus 로고    scopus 로고
    • Genome-wide analysis of microsatellite repeats in humans: their abundance and density in specific genomic regions
    • Subramanian S., et al. Genome-wide analysis of microsatellite repeats in humans: their abundance and density in specific genomic regions. Genome Biol. 4 (2003) R13
    • (2003) Genome Biol. , vol.4
    • Subramanian, S.1
  • 71
    • 62149119245 scopus 로고    scopus 로고
    • Salichs, E. et al. (2008) Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment. PloS Genet. 5, e1000397. doi:10.1371/journal.pgen.1000397 (www.plosgenetics.org)
    • Salichs, E. et al. (2008) Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment. PloS Genet. 5, e1000397. doi:10.1371/journal.pgen.1000397 (www.plosgenetics.org)
  • 72
    • 77950461601 scopus 로고    scopus 로고
    • Conrad, D.F. et al. (2009) Origins and functional impact of copy number variation in the human genome. Nature doi:10.1038/nature08516 (www.nature.com), Epub ahead of print, doi:10.1038/nature08516z
    • Conrad, D.F. et al. (2009) Origins and functional impact of copy number variation in the human genome. Nature doi:10.1038/nature08516 (www.nature.com), Epub ahead of print, doi:10.1038/nature08516z
  • 73
    • 67650001851 scopus 로고    scopus 로고
    • Complex human chromosomal and genomic rearrangements
    • Zhang F., et al. Complex human chromosomal and genomic rearrangements. Trends Genet. 25 (2009) 298-307
    • (2009) Trends Genet. , vol.25 , pp. 298-307
    • Zhang, F.1
  • 74
    • 63149156282 scopus 로고    scopus 로고
    • Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations
    • Bruce H.A., et al. Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations. Psychiatr. Genet. 19 (2009) 64-71
    • (2009) Psychiatr. Genet. , vol.19 , pp. 64-71
    • Bruce, H.A.1
  • 75
    • 33744936003 scopus 로고    scopus 로고
    • Tandemly repeated DNA: why should anyone care?
    • Armour J.A. Tandemly repeated DNA: why should anyone care?. Mutat. Res. 598 (2006) 6-14
    • (2006) Mutat. Res. , vol.598 , pp. 6-14
    • Armour, J.A.1
  • 76
    • 44349132708 scopus 로고    scopus 로고
    • Common and rare variants in multifactorial susceptibility to common diseases
    • Bodmer W., and Bonilla C. Common and rare variants in multifactorial susceptibility to common diseases. Nat. Genet. 40 (2008) 695-701
    • (2008) Nat. Genet. , vol.40 , pp. 695-701
    • Bodmer, W.1    Bonilla, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.