메뉴 건너뛰기




Volumn 72, Issue 2, 2015, Pages 204-209

Stages versus subsets: Invariant natural killer T cell lineage differentiation

Author keywords

Innate immunity; Lineage differentiation; T cell

Indexed keywords

CYTOKINE; E PROTEIN; INHIBITOR OF DIFFERENTIATION PROTEIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

EID: 84923792705     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2014.12.005     Document Type: Review
Times cited : (18)

References (63)
  • 2
    • 84907008497 scopus 로고    scopus 로고
    • IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset
    • Sag D., et al. IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset. J Clin Invest 2014, 124(9):3725-3740.
    • (2014) J Clin Invest , vol.124 , Issue.9 , pp. 3725-3740
    • Sag, D.1
  • 3
    • 0347776209 scopus 로고    scopus 로고
    • Mechanism of CD1d-restricted natural killer T cell activation during microbial infection
    • Brigl M., et al. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat Immunol 2003, 4(12):1230-1237.
    • (2003) Nat Immunol , vol.4 , Issue.12 , pp. 1230-1237
    • Brigl, M.1
  • 4
    • 78649866460 scopus 로고    scopus 로고
    • Natural killer T cells: innate lymphocytes positioned as a bridge between acute and chronic inflammation?
    • Fox L., Hegde S., Gumperz J.E. Natural killer T cells: innate lymphocytes positioned as a bridge between acute and chronic inflammation?. Microbes Infect 2010, 12(14-15):1125-1133.
    • (2010) Microbes Infect , vol.12 , Issue.14-15 , pp. 1125-1133
    • Fox, L.1    Hegde, S.2    Gumperz, J.E.3
  • 5
    • 20144389877 scopus 로고    scopus 로고
    • Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
    • Mattner J., et al. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 2005, 434(7032):525-529.
    • (2005) Nature , vol.434 , Issue.7032 , pp. 525-529
    • Mattner, J.1
  • 6
    • 68149163481 scopus 로고    scopus 로고
    • Innate-like recognition of microbes by invariant natural killer T cells
    • Kronenberg M., Kinjo Y. Innate-like recognition of microbes by invariant natural killer T cells. Curr Opin Immunol 2009, 21(4):391-396.
    • (2009) Curr Opin Immunol , vol.21 , Issue.4 , pp. 391-396
    • Kronenberg, M.1    Kinjo, Y.2
  • 7
    • 77953460077 scopus 로고    scopus 로고
    • Invariant natural killer T cell-based immunotherapy for cancer
    • Motohashi S., Nakayama T. Invariant natural killer T cell-based immunotherapy for cancer. Immunotherapy 2009, 1(1):73-82.
    • (2009) Immunotherapy , vol.1 , Issue.1 , pp. 73-82
    • Motohashi, S.1    Nakayama, T.2
  • 8
    • 78650575791 scopus 로고    scopus 로고
    • Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens
    • Van Kaer L., Parekh V.V., Wu L. Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens. Immunotherapy 2011, 3(1):59-75.
    • (2011) Immunotherapy , vol.3 , Issue.1 , pp. 59-75
    • Van Kaer, L.1    Parekh, V.V.2    Wu, L.3
  • 9
    • 62749198174 scopus 로고    scopus 로고
    • Natural killer T cells and autoimmune disease
    • Wu L., Van Kaer L. Natural killer T cells and autoimmune disease. Curr Mol Med 2009, 9(1):4-14.
    • (2009) Curr Mol Med , vol.9 , Issue.1 , pp. 4-14
    • Wu, L.1    Van Kaer, L.2
  • 10
    • 84872943896 scopus 로고    scopus 로고
    • Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions
    • Brennan P.J., Brigl M., Brenner M.B. Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions. Nat Rev Immunol 2013, 13(2):101-117.
    • (2013) Nat Rev Immunol , vol.13 , Issue.2 , pp. 101-117
    • Brennan, P.J.1    Brigl, M.2    Brenner, M.B.3
  • 11
    • 84877018173 scopus 로고    scopus 로고
    • Transcriptional regulation of the NKT cell lineage
    • Constantinides M.G., Bendelac A. Transcriptional regulation of the NKT cell lineage. Curr Opin Immunol 2013, 25(2):161-167.
    • (2013) Curr Opin Immunol , vol.25 , Issue.2 , pp. 161-167
    • Constantinides, M.G.1    Bendelac, A.2
  • 12
    • 68149164473 scopus 로고    scopus 로고
    • + and respond preferentially under inflammatory conditions
    • + and respond preferentially under inflammatory conditions. J Immunol 2009, 183(3):2142-2149.
    • (2009) J Immunol , vol.183 , Issue.3 , pp. 2142-2149
    • Doisne, J.M.1
  • 13
    • 84886673181 scopus 로고    scopus 로고
    • Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells
    • Lee Y.J., et al. Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells. Nat Immunol 2013, 14(11):1146-1154.
    • (2013) Nat Immunol , vol.14 , Issue.11 , pp. 1146-1154
    • Lee, Y.J.1
  • 14
    • 34249059942 scopus 로고    scopus 로고
    • Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia
    • Michel M.L., et al. Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia. J Exp Med 2007, 204(5):995-1001.
    • (2007) J Exp Med , vol.204 , Issue.5 , pp. 995-1001
    • Michel, M.L.1
  • 15
    • 84857488339 scopus 로고    scopus 로고
    • Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokines
    • Watarai H., et al. Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokines. PLoS Biol 2012, 10(2):e1001255.
    • (2012) PLoS Biol , vol.10 , Issue.2 , pp. e1001255
    • Watarai, H.1
  • 16
    • 1842785209 scopus 로고    scopus 로고
    • T-bet regulates the terminal maturation and homeostasis of NK and Vα14i NKT cells
    • Townsend M.J., et al. T-bet regulates the terminal maturation and homeostasis of NK and Vα14i NKT cells. Immunity 2004, 20(4):477-494.
    • (2004) Immunity , vol.20 , Issue.4 , pp. 477-494
    • Townsend, M.J.1
  • 17
    • 0036794405 scopus 로고    scopus 로고
    • Homeostasis of Vα14i NKT cells
    • Matsuda J.L., et al. Homeostasis of Vα14i NKT cells. Nat Immunol 2002, 3(10):966-974.
    • (2002) Nat Immunol , vol.3 , Issue.10 , pp. 966-974
    • Matsuda, J.L.1
  • 18
    • 27544442994 scopus 로고    scopus 로고
    • Helix-loop-helix proteins and lymphocyte development
    • Murre C. Helix-loop-helix proteins and lymphocyte development. Nat Immunol 2005, 6(11):1079-1086.
    • (2005) Nat Immunol , vol.6 , Issue.11 , pp. 1079-1086
    • Murre, C.1
  • 19
    • 73349117846 scopus 로고    scopus 로고
    • Transcriptional regulator Id2 controls survival of hepatic NKT cells
    • Monticelli L.A., et al. Transcriptional regulator Id2 controls survival of hepatic NKT cells. Proc Natl Acad Sci USA 2009, 106(46):19461-19466.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.46 , pp. 19461-19466
    • Monticelli, L.A.1
  • 20
    • 84896507471 scopus 로고    scopus 로고
    • E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation
    • D'Cruz L.M., et al. E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation. J Immunol 2014, 192(5):2227-2236.
    • (2014) J Immunol , vol.192 , Issue.5 , pp. 2227-2236
    • D'Cruz, L.M.1
  • 21
    • 84887436010 scopus 로고    scopus 로고
    • Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets
    • Hu T., et al. Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets. J Immunol 2013, 191(10):5065-5073.
    • (2013) J Immunol , vol.191 , Issue.10 , pp. 5065-5073
    • Hu, T.1
  • 22
    • 58149289887 scopus 로고    scopus 로고
    • A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity
    • Terashima A., et al. A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity. J Exp Med 2008, 205(12):2727-2733.
    • (2008) J Exp Med , vol.205 , Issue.12 , pp. 2727-2733
    • Terashima, A.1
  • 23
    • 33750828624 scopus 로고    scopus 로고
    • GATA-3 regulates the development and function of invariant NKT cells
    • Kim P.J., et al. GATA-3 regulates the development and function of invariant NKT cells. J Immunol 2006, 177(10):6650-6659.
    • (2006) J Immunol , vol.177 , Issue.10 , pp. 6650-6659
    • Kim, P.J.1
  • 24
    • 84890362107 scopus 로고    scopus 로고
    • Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development
    • Verykokakis M., et al. Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development. J Immunol 2013, 191(12):5973-5983.
    • (2013) J Immunol , vol.191 , Issue.12 , pp. 5973-5983
    • Verykokakis, M.1
  • 25
    • 84867051939 scopus 로고    scopus 로고
    • Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
    • Schmitz R., et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 2012, 490(7418):116-120.
    • (2012) Nature , vol.490 , Issue.7418 , pp. 116-120
    • Schmitz, R.1
  • 26
    • 76949089741 scopus 로고    scopus 로고
    • An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells
    • D'Cruz L.M., et al. An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells. Nat Immunol 2010, 11(3):240-249.
    • (2010) Nat Immunol , vol.11 , Issue.3 , pp. 240-249
    • D'Cruz, L.M.1
  • 27
    • 81255144662 scopus 로고    scopus 로고
    • The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets
    • Yang C.Y., et al. The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets. Nat Immunol 2011, 12(12):1221-1229.
    • (2011) Nat Immunol , vol.12 , Issue.12 , pp. 1221-1229
    • Yang, C.Y.1
  • 28
    • 84857190947 scopus 로고    scopus 로고
    • Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling
    • Seiler M.P., et al. Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nat Immunol 2012, 13(3):264-271.
    • (2012) Nat Immunol , vol.13 , Issue.3 , pp. 264-271
    • Seiler, M.P.1
  • 29
    • 49649123906 scopus 로고    scopus 로고
    • Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population
    • Coquet J.M., et al. Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population. Proc Natl Acad Sci USA 2008, 105(32):11287-11292.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.32 , pp. 11287-11292
    • Coquet, J.M.1
  • 30
    • 58149384437 scopus 로고    scopus 로고
    • Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation
    • Michel M.L., et al. Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation. Proc Natl Acad Sci USA 2008, 105(50):19845-19850.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.50 , pp. 19845-19850
    • Michel, M.L.1
  • 31
    • 42649110747 scopus 로고    scopus 로고
    • Cutting edge: NKT cells constitutively express IL-23 receptor and RORγt and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion
    • Rachitskaya A.V., et al. Cutting edge: NKT cells constitutively express IL-23 receptor and RORγt and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion. J Immunol 2008, 180(8):5167-5171.
    • (2008) J Immunol , vol.180 , Issue.8 , pp. 5167-5171
    • Rachitskaya, A.V.1
  • 32
    • 39549106479 scopus 로고    scopus 로고
    • Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
    • Pichavant M., et al. Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17. J Exp Med 2008, 205(2):385-393.
    • (2008) J Exp Med , vol.205 , Issue.2 , pp. 385-393
    • Pichavant, M.1
  • 33
    • 53049086275 scopus 로고    scopus 로고
    • Invariant NKT cells produce IL-17 through IL-23-dependent and -independent pathways with potential modulation of Th17 response in collagen-induced arthritis
    • Yoshiga Y., et al. Invariant NKT cells produce IL-17 through IL-23-dependent and -independent pathways with potential modulation of Th17 response in collagen-induced arthritis. Int J Mol Med 2008, 22(3):369-374.
    • (2008) Int J Mol Med , vol.22 , Issue.3 , pp. 369-374
    • Yoshiga, Y.1
  • 34
    • 79251578351 scopus 로고    scopus 로고
    • Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria
    • Doisne J.M., et al. Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria. J Immunol 2011, 186(2):662-666.
    • (2011) J Immunol , vol.186 , Issue.2 , pp. 662-666
    • Doisne, J.M.1
  • 35
    • 80052966551 scopus 로고    scopus 로고
    • Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria
    • Kinjo Y., et al. Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nat Immunol 2011, 12(10):966-974.
    • (2011) Nat Immunol , vol.12 , Issue.10 , pp. 966-974
    • Kinjo, Y.1
  • 36
    • 84859809966 scopus 로고    scopus 로고
    • Development and function of murine RORγt+ iNKT cells are under TGF-β signaling control
    • Havenar-Daughton C., et al. Development and function of murine RORγt+ iNKT cells are under TGF-β signaling control. Blood 2012, 119(15):3486-3494.
    • (2012) Blood , vol.119 , Issue.15 , pp. 3486-3494
    • Havenar-Daughton, C.1
  • 37
    • 80052923989 scopus 로고    scopus 로고
    • IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression
    • Milpied P., et al. IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression. Blood 2011, 118(11):2993-3002.
    • (2011) Blood , vol.118 , Issue.11 , pp. 2993-3002
    • Milpied, P.1
  • 38
    • 46949088806 scopus 로고    scopus 로고
    • Neuropilin-1 is a receptor for transforming growth factor β-1, activates its latent form, and promotes regulatory T cell activity
    • Glinka Y., Prud'homme G.J. Neuropilin-1 is a receptor for transforming growth factor β-1, activates its latent form, and promotes regulatory T cell activity. J Leukoc Biol 2008, 84(1):302-310.
    • (2008) J Leukoc Biol , vol.84 , Issue.1 , pp. 302-310
    • Glinka, Y.1    Prud'homme, G.J.2
  • 39
    • 84869767226 scopus 로고    scopus 로고
    • ZBTB7B (Th-POK) regulates the development of IL-17-producing CD1d-restricted mouse NKT cells
    • Enders A., et al. ZBTB7B (Th-POK) regulates the development of IL-17-producing CD1d-restricted mouse NKT cells. J Immunol 2012, 189(11):5240-5249.
    • (2012) J Immunol , vol.189 , Issue.11 , pp. 5240-5249
    • Enders, A.1
  • 40
    • 84870551898 scopus 로고    scopus 로고
    • The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells
    • Engel I., et al. The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells. Blood 2012, 120(23):4524-4532.
    • (2012) Blood , vol.120 , Issue.23 , pp. 4524-4532
    • Engel, I.1
  • 41
    • 83755166410 scopus 로고    scopus 로고
    • Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses
    • Chang P.P., et al. Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses. Nat Immunol 2012, 13(1):35-43.
    • (2012) Nat Immunol , vol.13 , Issue.1 , pp. 35-43
    • Chang, P.P.1
  • 42
    • 83755166409 scopus 로고    scopus 로고
    • Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner
    • King I.L., et al. Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner. Nat Immunol 2012, 13(1):44-50.
    • (2012) Nat Immunol , vol.13 , Issue.1 , pp. 44-50
    • King, I.L.1
  • 43
    • 46149094402 scopus 로고    scopus 로고
    • B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo
    • Barral P., et al. B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo. Proc Natl Acad Sci USA 2008, 105(24):8345-8350.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.24 , pp. 8345-8350
    • Barral, P.1
  • 44
    • 46149103655 scopus 로고    scopus 로고
    • NK T cells provide lipid antigen-specific cognate help for B cells
    • Leadbetter E.A., et al. NK T cells provide lipid antigen-specific cognate help for B cells. Proc Natl Acad Sci USA 2008, 105(24):8339-8344.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.24 , pp. 8339-8344
    • Leadbetter, E.A.1
  • 45
    • 58849166273 scopus 로고    scopus 로고
    • NKT-cell help to B lymphocytes can occur independently of cognate interaction
    • Tonti E., et al. NKT-cell help to B lymphocytes can occur independently of cognate interaction. Blood 2009, 113(2):370-376.
    • (2009) Blood , vol.113 , Issue.2 , pp. 370-376
    • Tonti, E.1
  • 46
    • 83755220439 scopus 로고    scopus 로고
    • Innate iNKT cell help to B cells: fast but does not last
    • Lehuen A., Fazilleau N. Innate iNKT cell help to B cells: fast but does not last. Nat Immunol 2012, 13(1):11-13.
    • (2012) Nat Immunol , vol.13 , Issue.1 , pp. 11-13
    • Lehuen, A.1    Fazilleau, N.2
  • 47
    • 84885060911 scopus 로고    scopus 로고
    • Natural killer T (NKT)-B-cell interactions promote prolonged antibody responses and long-term memory to pneumococcal capsular polysaccharides
    • Bai L., et al. Natural killer T (NKT)-B-cell interactions promote prolonged antibody responses and long-term memory to pneumococcal capsular polysaccharides. Proc Natl Acad Sci USA 2013, 110(40):16097-16102.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.40 , pp. 16097-16102
    • Bai, L.1
  • 48
    • 24644433401 scopus 로고    scopus 로고
    • Glycolipid antigen induces long-term natural killer T cell anergy in mice
    • Parekh V.V., et al. Glycolipid antigen induces long-term natural killer T cell anergy in mice. J Clin Invest 2005, 115(9):2572-2583.
    • (2005) J Clin Invest , vol.115 , Issue.9 , pp. 2572-2583
    • Parekh, V.V.1
  • 49
    • 24644456381 scopus 로고    scopus 로고
    • Activation or anergy: NKT cells are stunned by α-galactosylceramide
    • Sullivan B.A., Kronenberg M. Activation or anergy: NKT cells are stunned by α-galactosylceramide. J Clin Invest 2005, 115(9):2328-2329.
    • (2005) J Clin Invest , vol.115 , Issue.9 , pp. 2328-2329
    • Sullivan, B.A.1    Kronenberg, M.2
  • 50
    • 58149104377 scopus 로고    scopus 로고
    • Harnessing invariant NKT cells in vaccination strategies
    • Cerundolo V., et al. Harnessing invariant NKT cells in vaccination strategies. Nat Rev Immunol 2009, 9(1):28-38.
    • (2009) Nat Rev Immunol , vol.9 , Issue.1 , pp. 28-38
    • Cerundolo, V.1
  • 51
    • 84897003491 scopus 로고    scopus 로고
    • Biology of CD1- and MR1-restricted T cells
    • Salio M., et al. Biology of CD1- and MR1-restricted T cells. Annu Rev Immunol 2014, 32:323-366.
    • (2014) Annu Rev Immunol , vol.32 , pp. 323-366
    • Salio, M.1
  • 52
    • 53149100521 scopus 로고    scopus 로고
    • Rapid NKT cell responses are self-terminating during the course of microbial infection
    • Chiba A., et al. Rapid NKT cell responses are self-terminating during the course of microbial infection. J Immunol 2008, 181(4):2292-2302.
    • (2008) J Immunol , vol.181 , Issue.4 , pp. 2292-2302
    • Chiba, A.1
  • 53
    • 84901699999 scopus 로고    scopus 로고
    • Id2 represses E2A-mediated activation of IL-10 expression in T cells
    • Masson F., et al. Id2 represses E2A-mediated activation of IL-10 expression in T cells. Blood 2014, 123(22):3420-3428.
    • (2014) Blood , vol.123 , Issue.22 , pp. 3420-3428
    • Masson, F.1
  • 54
    • 13544262688 scopus 로고    scopus 로고
    • Direct regulatory role of NKT cells in allogeneic graft survival is dependent on the quantitative strength of antigenicity
    • Oh K., et al. Direct regulatory role of NKT cells in allogeneic graft survival is dependent on the quantitative strength of antigenicity. J Immunol 2005, 174(4):2030-2036.
    • (2005) J Immunol , vol.174 , Issue.4 , pp. 2030-2036
    • Oh, K.1
  • 55
    • 84863808516 scopus 로고    scopus 로고
    • Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4
    • Ji Y., et al. Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4. J Biol Chem 2012, 287(29):24378-24386.
    • (2012) J Biol Chem , vol.287 , Issue.29 , pp. 24378-24386
    • Ji, Y.1
  • 56
    • 84859997837 scopus 로고    scopus 로고
    • Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity
    • Ji Y., et al. Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity. J Biol Chem 2012, 287(17):13561-13571.
    • (2012) J Biol Chem , vol.287 , Issue.17 , pp. 13561-13571
    • Ji, Y.1
  • 57
    • 84866520055 scopus 로고    scopus 로고
    • Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production
    • Lynch L., et al. Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production. Immunity 2012, 37(3):574-587.
    • (2012) Immunity , vol.37 , Issue.3 , pp. 574-587
    • Lynch, L.1
  • 58
    • 84871871453 scopus 로고    scopus 로고
    • A novel function of adipocytes in lipid antigen presentation to iNKT cells
    • Huh J.Y., et al. A novel function of adipocytes in lipid antigen presentation to iNKT cells. Mol Cell Biol 2013, 33(2):328-339.
    • (2013) Mol Cell Biol , vol.33 , Issue.2 , pp. 328-339
    • Huh, J.Y.1
  • 59
    • 77956943528 scopus 로고    scopus 로고
    • Identification of regulatory Foxp3+ invariant NKT cells induced by TGF-β
    • Monteiro M., et al. Identification of regulatory Foxp3+ invariant NKT cells induced by TGF-β. J Immunol 2010, 185(4):2157-2163.
    • (2010) J Immunol , vol.185 , Issue.4 , pp. 2157-2163
    • Monteiro, M.1
  • 60
    • 84855999082 scopus 로고    scopus 로고
    • Rapamycin combined with TGF-β converts human invariant NKT cells into suppressive Foxp3+ regulatory cells
    • Moreira-Teixeira L., et al. Rapamycin combined with TGF-β converts human invariant NKT cells into suppressive Foxp3+ regulatory cells. J Immunol 2012, 188(2):624-631.
    • (2012) J Immunol , vol.188 , Issue.2 , pp. 624-631
    • Moreira-Teixeira, L.1
  • 61
    • 79960727504 scopus 로고    scopus 로고
    • Characterization of human invariant natural killer T cells expressing FoxP3
    • Engelmann P., et al. Characterization of human invariant natural killer T cells expressing FoxP3. Int Immunol 2011, 23(8):473-484.
    • (2011) Int Immunol , vol.23 , Issue.8 , pp. 473-484
    • Engelmann, P.1
  • 62
    • 61449255982 scopus 로고    scopus 로고
    • A phase I-II study of α-galactosylceramide-pulsed IL-2/GM-CSF-cultured peripheral blood mononuclear cells in patients with advanced and recurrent non-small cell lung cancer
    • Motohashi S., et al. A phase I-II study of α-galactosylceramide-pulsed IL-2/GM-CSF-cultured peripheral blood mononuclear cells in patients with advanced and recurrent non-small cell lung cancer. J Immunol 2009, 182(4):2492-2501.
    • (2009) J Immunol , vol.182 , Issue.4 , pp. 2492-2501
    • Motohashi, S.1
  • 63
    • 72049133156 scopus 로고    scopus 로고
    • Alpha-galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial
    • Woltman A.M., et al. Alpha-galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial. Antivir Ther 2009, 14(6):809-818.
    • (2009) Antivir Ther , vol.14 , Issue.6 , pp. 809-818
    • Woltman, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.