Analysis of adult cerebral cortex and hippocampus transcriptomes reveals unique molecular changes in the Ts1Cje mouse model of down syndrome

Brain Pathology

Volumn 25, Issue 1, 2015, Pages 11-23

  Guedj, Faycal ^a   Pennings, Jeroen L A ^b   Wick, Heather C ^c   Bianchi, Diana W ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^c Tufts University   (United States)

Author keywords

Brain; Down syndrome; gene expression; mouse model; pathway dysregulation

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GLUTATHIONE TRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; RNA; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTOME; COPPER ZINC SUPEROXIDE DISMUTASE; HOMEODOMAIN PROTEIN; NUCLEAR PROTEIN; SND1 PROTEIN, MOUSE; SUPEROXIDE DISMUTASE; ZHX2 PROTEIN, MOUSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CYB5R1 GENE; DCAF7 GENE; DNAHC11 GENE; DOWN REGULATION; DOWN SYNDROME; ENZYME ACTIVITY; EXON; FEMALE; FSBP GENE; GENE; GENE DOSAGE; GENE EXPRESSION; GENE ONTOLOGY; GENE OVEREXPRESSION; HIPPOCAMPUS; HORMONE METABOLISM; ITGB8 GENE; MALE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMELLING; SND1 GENE; TMEM196 GENE; UPREGULATION; VMN2R110 GENE; WILD TYPE; ZHX2 GENE; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; COPY NUMBER VARIATION; DISEASE MODEL; METABOLISM; MICROARRAY ANALYSIS; MUTANT MOUSE STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DNA COPY NUMBER VARIATIONS; DOWN SYNDROME; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; HOMEODOMAIN PROTEINS; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICROARRAY ANALYSIS; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE; TRANSCRIPTOME;

EID: 84923565187     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/bpa.12151     Document Type: Article

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