Wdr68 Requires Nuclear Access for Craniofacial Development

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Wang, Bingyan ^a   Doan, Diana ^a   Roman Petersen, Yanett ^a   Alvarado, Estibaliz ^a   Alvarado, Gregory ^a   Bhandari, Ajay ^a   Mohanty, Aditya ^a   Mohanty, Sudipta ^a   Nissen, Robert M ^a  

^a CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; MYOGENIN; PROTEIN WDR68; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CRANIOFACIAL DEVELOPMENT; EMBRYO; GENE OVEREXPRESSION; GENE REPRESSION; HETEROZYGOSITY; HOMOZYGOSITY; IMMUNOPRECIPITATION; MYOG GENE; NONHUMAN; NUCLEAR EXPORT SIGNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ZEBRA FISH;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL NUCLEUS; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; MICE; MYOBLASTS; MYOGENIN; NUCLEAR EXPORT SIGNALS; NUCLEAR PROTEINS; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SKULL; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO;

EID: 84872801049     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054363     Document Type: Article

References (35)

1. Nissen RM, Amsterdam A, Hopkins N, (2006) A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for Endothelin-1 expression. BMC Dev Biol 6: 28.
2. Mazmanian G, Kovshilovsky M, Yen D, Mohanty A, Mohanty S, et al. (2010) The zebrafish dyrk1b gene is important for endoderm formation. Genesis 48: 20-30.
3. Ritterhoff S, Farah CM, Grabitzki J, Lochnit G, Skurat AV, et al. (2010) The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions. Embo J 29: 3750-3761.
4. de Vetten N, Quattrocchio F, Mol J, Koes R, (1997) The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals. Genes Dev 11: 1422-1434.
5. Wang Y, Wu JF, Nakamichi N, Sakakibara H, Nam HG, et al. (2011) LIGHT-REGULATED WD1 and PSEUDO-RESPONSE REGULATOR9 form a positive feedback regulatory loop in the Arabidopsis circadian clock. Plant Cell 23: 486-498.
6. Stirnimann CU, Petsalaki E, Russell RB, Muller CW, (2010) WD40 proteins propel cellular networks. Trends Biochem Sci 35: 565-574.
7. Skurat AV, Dietrich AD, (2004) Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases. J Biol Chem 279: 2490-2498.
8. Lee K, Deng X, Friedman E, (2000) Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells. Cancer Res 60: 3631-3637.
9. Deng X, Ewton DZ, Friedman E, (2009) Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species. Cancer Res 69: 3317-3324.
10. Jin K, Park S, Ewton DZ, Friedman E, (2007) The survival kinase Mirk/Dyrk1B is a downstream effector of oncogenic K-ras in pancreatic cancer. Cancer Res 67: 7247-7255.
11. Lauth M, Bergstrom A, Shimokawa T, Tostar U, Jin Q, et al. (2010) DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS. Nat Struct Mol Biol 17: 718-725.
12. Deng X, Ewton DZ, Mercer SE, Friedman E, (2005) Mirk/dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation. J Biol Chem 280: 4894-4905.
13. Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, et al. (2004) A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Nat Cell Biol 6: 97-105.
14. Russell M, Lange-Carter CA, Johnson GL, (1995) Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1). J Biol Chem 270: 11757-11760.
15. Deng X, Ewton DZ, Pawlikowski B, Maimone M, Friedman E, (2003) Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation. J Biol Chem 278: 41347-41354.
16. Mercer SE, Ewton DZ, Deng X, Lim S, Mazur TR, et al. (2005) Mirk/Dyrk1B Mediates Survival during the Differentiation of C2C12 Myoblasts. J Biol Chem 280: 25788-25801.
17. Mercer SE, Ewton DZ, Shah S, Naqvi A, Friedman E, (2006) Mirk/Dyrk1b mediates cell survival in rhabdomyosarcomas. Cancer Res 66: 5143-5150.
18. Friedman E, (2007) Mirk/Dyrk1B in cancer. J Cell Biochem 102: 274-279.
19. Deng X, Ewton DZ, Li S, Naqvi A, Mercer SE, et al. (2006) The kinase Mirk/Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma. Cancer Res 66: 4149-4158.
20. Lim S, Jin K, Friedman E, (2002) Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha. J Biol Chem 277: 25040-25046.
21. Clouthier DE, Schilling TF, (2004) Understanding endothelin-1 function during craniofacial development in the mouse and zebrafish. Birth Defects Res C Embryo Today 72: 190-199.
22. Kimmel CB, Miller CT, Kruze G, Ullmann B, BreMiller RA, et al. (1998) The shaping of pharyngeal cartilages during early development of the zebrafish. Dev Biol 203: 245-263.
23. Fukuda M, Gotoh I, Gotoh Y, Nishida E, (1996) Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal. J Biol Chem 271: 20024-20028.
24. Ayer DE, Laherty CD, Lawrence QA, Armstrong AP, Eisenman RN, (1996) Mad proteins contain a dominant transcription repression domain. Mol Cell Biol 16: 5772-5781.
25. Laherty CD, Yang WM, Sun JM, Davie JR, Seto E, et al. (1997) Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 89: 349-356.
26. Lyons SE, Shue BC, Lei L, Oates AC, Zon LI, et al. (2001) Molecular cloning, genetic mapping, and expression analysis of four zebrafish c/ebp genes. Gene 281: 43-51.
27. Williamson EA, Xu HN, Gombart AF, Verbeek W, Chumakov AM, et al. (1998) Identification of transcriptional activation and repression domains in human CCAAT/enhancer-binding protein epsilon. J Biol Chem 273: 14796-14804.
28. Weintraub H, (1993) The MyoD family and myogenesis: redundancy, networks, and thresholds. Cell 75: 1241-1244.
29. Berkes CA, Tapscott SJ, (2005) MyoD and the transcriptional control of myogenesis. Semin Cell Dev Biol 16: 585-595.
30. Miyata Y, Nishida E, (2011) DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation. Biochim Biophys Acta 1813: 1728-1739.
31. Mercer SE, Friedman E, (2006) Mirk/Dyrk1B: a multifunctional dual-specificity kinase involved in growth arrest, differentiation, and cell survival. Cell Biochem Biophys 45: 303-315.
32. Miller CT, Swartz ME, Khuu PA, Walker MB, Eberhart JK, et al. (2007) mef2ca is required in cranial neural crest to effect Endothelin1 signaling in zebrafish. Dev Biol 308: 144-157.
33. Yujiri T, Ware M, Widmann C, Oyer R, Russell D, et al. (2000) MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation. Proc Natl Acad Sci U S A 97: 7272-7277.
34. Berkes CA, Bergstrom DA, Penn BH, Seaver KJ, Knoepfler PS, et al. (2004) Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential. Mol Cell 14: 465-477.
35. Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S, et al. (2004) Identification of 315 genes essential for early zebrafish development. Proc Natl Acad Sci U S A 101: 12792-12797.