메뉴 건너뛰기




Volumn 10, Issue 2, 2015, Pages

Molecular characterization of the peripheral airway field of cancerization in lung adenocarcinoma

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; MESSENGER RNA;

EID: 84923382382     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118132     Document Type: Article
Times cited : (17)

References (66)
  • 1
    • 84855792427 scopus 로고    scopus 로고
    • Cancer statistics, 2012
    • PMID: 22237781
    • Siegel R, Naishadham D, Jemal A (2012) Cancer statistics, 2012. CA Cancer J Clin 62: 10-29. doi: 10.3322/caac.20138 PMID: 22237781
    • (2012) CA Cancer J Clin , vol.62 , pp. 10-29
    • Siegel, R.1    Naishadham, D.2    Jemal, A.3
  • 2
    • 33750315764 scopus 로고    scopus 로고
    • Survival of Patients with Stage I Lung Cancer Detected on CT Screening
    • PMID: 17065637
    • The International Early Lung Cancer Action Program Investigators (2006) Survival of Patients with Stage I Lung Cancer Detected on CT Screening. New England Journal of Medicine 355: 1763-1771. PMID: 17065637
    • (2006) New England Journal of Medicine , vol.355 , pp. 1763-1771
  • 3
    • 65249180631 scopus 로고    scopus 로고
    • Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers
    • PMID: 19357784
    • Steiling K, Kadar AY, Bergerat A, Flanigon J, Sridhar S, et al. (2009) Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers. PLoS One 4: e5043. doi: 10.1371/journal.pone.0005043 PMID: 19357784
    • (2009) PLoS One , vol.4 , pp. e5043
    • Steiling, K.1    Kadar, A.Y.2    Bergerat, A.3    Flanigon, J.4    Sridhar, S.5
  • 4
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin
    • PMID: 13094644
    • Slaughter DP, Southwick HW, Smejkal W (1953) Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 6: 963-968. PMID: 13094644
    • (1953) Cancer , vol.6 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 5
    • 0032578509 scopus 로고    scopus 로고
    • Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis
    • PMID: 9751761
    • Belinsky SA, Nikula KJ, Palmisano WA, Michels R, Saccomanno G, et al. (1998) Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci U S A 95: 11891-11896. PMID: 9751761
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 11891-11896
    • Belinsky, S.A.1    Nikula, K.J.2    Palmisano, W.A.3    Michels, R.4    Saccomanno, G.5
  • 6
    • 0030772811 scopus 로고    scopus 로고
    • Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis
    • PMID: 9329980
    • Franklin WA, Gazdar AF, Haney J, Wistuba II, La Rosa FG, et al. (1997) Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis. J Clin Invest 100: 2133-2137. PMID: 9329980
    • (1997) J Clin Invest , vol.100 , pp. 2133-2137
    • Franklin, W.A.1    Gazdar, A.F.2    Haney, J.3    Wistuba, I.I.4    La Rosa, F.G.5
  • 7
    • 4143132121 scopus 로고    scopus 로고
    • Promoter hypermethylation of resected bronchial margins: A field defect of changes?
    • PMID: 15297416
    • Guo M, House MG, Hooker C, Han Y, Heath E, et al. (2004) Promoter hypermethylation of resected bronchial margins: a field defect of changes? Clin Cancer Res 10: 5131-5136. PMID: 15297416
    • (2004) Clin Cancer Res , vol.10 , pp. 5131-5136
    • Guo, M.1    House, M.G.2    Hooker, C.3    Han, Y.4    Heath, E.5
  • 8
    • 0029983092 scopus 로고    scopus 로고
    • Detection of K-ras gene mutations in non-neoplastic lung tissue and lung cancers
    • PMID: 8616804
    • Nelson MA, Wymer J, Clements N Jr (1996) Detection of K-ras gene mutations in non-neoplastic lung tissue and lung cancers. Cancer Lett 103: 115-121. PMID: 8616804
    • (1996) Cancer Lett , vol.103 , pp. 115-121
    • Nelson, M.A.1    Wymer, J.2    Clements, N.3
  • 9
    • 0032809589 scopus 로고    scopus 로고
    • Loss of heterozygosity in epithelial cells obtained by bronchial brushing: Clinical utility in lung cancer
    • PMID: 10473082
    • Powell CA, Klares S, O'Connor G, Brody JS (1999) Loss of heterozygosity in epithelial cells obtained by bronchial brushing: clinical utility in lung cancer. Clin Cancer Res 5: 2025-2034. PMID: 10473082
    • (1999) Clin Cancer Res , vol.5 , pp. 2025-2034
    • Powell, C.A.1    Klares, S.2    O'Connor, G.3    Brody, J.S.4
  • 10
    • 24744461722 scopus 로고    scopus 로고
    • EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients
    • PMID: 16140919
    • Tang X, Shigematsu H, Bekele BN, Roth JA, Minna JD, et al. (2005) EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients. Cancer Res 65: 7568-7572. PMID: 16140919
    • (2005) Cancer Res , vol.65 , pp. 7568-7572
    • Tang, X.1    Shigematsu, H.2    Bekele, B.N.3    Roth, J.A.4    Minna, J.D.5
  • 11
    • 19244370711 scopus 로고    scopus 로고
    • High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints
    • PMID: 10766185
    • Wistuba II, Behrens C, Virmani AK, Mele G, Milchgrub S, et al. (2000) High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 60: 1949-1960. PMID: 10766185
    • (2000) Cancer Res , vol.60 , pp. 1949-1960
    • Wistuba, I.I.1    Behrens, C.2    Virmani, A.K.3    Mele, G.4    Milchgrub, S.5
  • 13
    • 82755194759 scopus 로고    scopus 로고
    • MiRNAs as regulators of the response to inhaled environmental toxins and airway carcinogenesis
    • PMID: 21549133
    • Perdomo C, Spira A, Schembri F (2011) MiRNAs as regulators of the response to inhaled environmental toxins and airway carcinogenesis. Mutat Res 717: 32-37. doi: 10.1016/j.mrfmmm.2011.04.005 PMID: 21549133
    • (2011) Mutat Res , vol.717 , pp. 32-37
    • Perdomo, C.1    Spira, A.2    Schembri, F.3
  • 14
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • PMID: 16461460
    • Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, et al. (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 103: 2257-2261. PMID: 16461460
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3    Ambs, S.4    Cimmino, A.5
  • 15
    • 84977478146 scopus 로고    scopus 로고
    • MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer
    • PMID: 21300873
    • Boeri M, Verri C, Conte D, Roz L, Modena P, et al. (2011) MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer. Proc Natl Acad Sci U S A 108: 3713-3718. doi: 10.1073/pnas.1100048108 PMID: 21300873
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3713-3718
    • Boeri, M.1    Verri, C.2    Conte, D.3    Roz, L.4    Modena, P.5
  • 16
    • 84858126071 scopus 로고    scopus 로고
    • MicroRNA dysregulation in cancer: Diagnostics, monitoring and therapeutics. A comprehensive review
    • PMID: 22351564
    • Iorio MV, Croce CM (2012) MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med 4: 143-159. doi: 10.1002/emmm.201100209 PMID: 22351564
    • (2012) EMBO Mol Med , vol.4 , pp. 143-159
    • Iorio, M.V.1    Croce, C.M.2
  • 17
    • 33847749502 scopus 로고    scopus 로고
    • Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer
    • PMID: 17334370
    • Spira A, Beane JE, Shah V, Steiling K, Liu G, et al. (2007) Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med 13: 361-366. PMID: 17334370
    • (2007) Nat Med , vol.13 , pp. 361-366
    • Spira, A.1    Beane, J.E.2    Shah, V.3    Steiling, K.4    Liu, G.5
  • 18
    • 33845881700 scopus 로고    scopus 로고
    • Modification of gene expression of the small airway epithelium in response to cigarette smoking
    • PMID: 17115125
    • Harvey BG, Heguy A, Leopold PL, Carolan BJ, Ferris B, et al. (2007) Modification of gene expression of the small airway epithelium in response to cigarette smoking. J Mol Med (Berl) 85: 39-53. PMID: 17115125
    • (2007) J Mol Med (Berl) , vol.85 , pp. 39-53
    • Harvey, B.G.1    Heguy, A.2    Leopold, P.L.3    Carolan, B.J.4    Ferris, B.5
  • 19
    • 33645406090 scopus 로고    scopus 로고
    • Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking
    • PMID: 16520944
    • Heguy A, O'Connor, Luettich K, Worgall S, Cieciuch A, et al. (2006) Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking. J Mol Med (Berl) 84: 318-328. PMID: 16520944
    • (2006) J Mol Med (Berl) , vol.84 , pp. 318-328
    • Heguy, A.1    O'Connor2    Luettich, K.3    Worgall, S.4    Cieciuch, A.5
  • 20
    • 84864464973 scopus 로고    scopus 로고
    • DIANA miRPath v.2.0: Investigating the combinatorial effect of microRNAs in pathways
    • PMID: 22649059
    • Vlachos IS, Kostoulas N, Vergoulis T, Georgakilas G, Reczko M, et al. (2012) DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Research 40: W498-W504. doi: 10.1093/nar/gks494 PMID: 22649059
    • (2012) Nucleic Acids Research , vol.40 , pp. W498-W504
    • Vlachos, I.S.1    Kostoulas, N.2    Vergoulis, T.3    Georgakilas, G.4    Reczko, M.5
  • 21
    • 80051559806 scopus 로고    scopus 로고
    • Identification of miR-374a as a prognostic marker for survival in patients with early-stage nonsmall cell lung cancer
    • PMID: 21748820
    • Vosa U, Vooder T, Kolde R, Fischer K, Valk K, et al. (2011) Identification of miR-374a as a prognostic marker for survival in patients with early-stage nonsmall cell lung cancer. Genes Chromosomes Cancer 50: 812-822. doi: 10.1002/gcc.20902 PMID: 21748820
    • (2011) Genes Chromosomes Cancer , vol.50 , pp. 812-822
    • Vosa, U.1    Vooder, T.2    Kolde, R.3    Fischer, K.4    Valk, K.5
  • 22
    • 0030936265 scopus 로고    scopus 로고
    • An achaete-scute homologue essential for neuroendocrine differentiation in the lung
    • PMID: 9126746
    • Borges M, Linnoila RI, van de Velde HJ, Chen H, Nelkin BD, et al. (1997) An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Nature 386: 852-855. PMID: 9126746
    • (1997) Nature , vol.386 , pp. 852-855
    • Borges, M.1    Linnoila, R.I.2    Van De Velde, H.J.3    Chen, H.4    Nelkin, B.D.5
  • 23
    • 0033885165 scopus 로고    scopus 로고
    • Constitutive Achaete-Scute Homologue-1 Promotes Airway Dysplasia and Lung Neuroendocrine Tumors in Transgenic Mice
    • PMID: 10945598
    • Linnoila RI, Zhao B, DeMayo JL, Nelkin BD, Baylin SB, et al. (2000) Constitutive Achaete-Scute Homologue-1 Promotes Airway Dysplasia and Lung Neuroendocrine Tumors in Transgenic Mice. Cancer Res 60: 4005-4009. PMID: 10945598
    • (2000) Cancer Res , vol.60 , pp. 4005-4009
    • Linnoila, R.I.1    Zhao, B.2    DeMayo, J.L.3    Nelkin, B.D.4    Baylin, S.B.5
  • 24
    • 84870508104 scopus 로고    scopus 로고
    • Multidirectional differentiation of Achaete-Scute homologue-1-defined progenitors in lung development and injury repair
    • PMID: 22878413
    • Li Y, Linnoila RI (2012) Multidirectional differentiation of Achaete-Scute homologue-1-defined progenitors in lung development and injury repair. Am J Respir Cell Mol Biol 47: 768-775. doi: 10.1165/rcmb.2012-0027OC PMID: 22878413
    • (2012) Am J Respir Cell Mol Biol , vol.47 , pp. 768-775
    • Li, Y.1    Linnoila, R.I.2
  • 25
    • 84868688221 scopus 로고    scopus 로고
    • Calcium tips the balance: A microtubule plus end to lattice binding switch operates in the carboxyl terminus of BPAG1n4
    • PMID: 22995871
    • Kapur M, Wang W, Maloney MT, Millan I, Lundin VF, et al. (2012) Calcium tips the balance: a microtubule plus end to lattice binding switch operates in the carboxyl terminus of BPAG1n4. EMBO Rep 13: 1021-1029. doi: 10.1038/embor.2012.140 PMID: 22995871
    • (2012) EMBO Rep , vol.13 , pp. 1021-1029
    • Kapur, M.1    Wang, W.2    Maloney, M.T.3    Millan, I.4    Lundin, V.F.5
  • 26
    • 65549130220 scopus 로고    scopus 로고
    • Rnd3 Regulation of the Actin Cytoskeleton Promotes Melanoma Migration and Invasive Outgrowth in Three Dimensions
    • PMID: 19244113
    • Klein RM, Aplin AE (2009) Rnd3 Regulation of the Actin Cytoskeleton Promotes Melanoma Migration and Invasive Outgrowth in Three Dimensions. Cancer Res 69: 2224-2233. doi: 10.1158/0008-5472.CAN-08-3201 PMID: 19244113
    • (2009) Cancer Res , vol.69 , pp. 2224-2233
    • Klein, R.M.1    Aplin, A.E.2
  • 27
    • 77956061393 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)
    • PMID: 20223231
    • Zhang JG, Wang JJ, Zhao F, Liu Q, Jiang K, et al. (2010) MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin Chim Acta 411: 846-852. doi: 10.1016/j.cca.2010.02.074 PMID: 20223231
    • (2010) Clin Chim Acta , vol.411 , pp. 846-852
    • Zhang, J.G.1    Wang, J.J.2    Zhao, F.3    Liu, Q.4    Jiang, K.5
  • 28
    • 33646348742 scopus 로고    scopus 로고
    • Prostaglandin E2 Regulates the Nuclear Receptor NR4A2 in Colorectal Cancer
    • PMID: 16293616
    • Holla VR, Mann JR, Shi Q, DuBois RN (2006) Prostaglandin E2 Regulates the Nuclear Receptor NR4A2 in Colorectal Cancer. Journal of Biological Chemistry 281: 2676-2682. PMID: 16293616
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 2676-2682
    • Holla, V.R.1    Mann, J.R.2    Shi, Q.3    DuBois, R.N.4
  • 29
    • 0032582679 scopus 로고    scopus 로고
    • DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis
    • PMID: 9786912
    • Sanjo H, Kawai T, Akira S (1998) DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis. J Biol Chem 273: 29066-29071. PMID: 9786912
    • (1998) J Biol Chem , vol.273 , pp. 29066-29071
    • Sanjo, H.1    Kawai, T.2    Akira, S.3
  • 31
    • 81755171479 scopus 로고    scopus 로고
    • Angiomotin-like2 gene (amotl2) is required for migration and proliferation of endothelial cells during angiogenesis
    • PMID: 21937427
    • Wang Y, Li Z, Xu P, Huang L, Tong J, et al. (2011) Angiomotin-like2 gene (amotl2) is required for migration and proliferation of endothelial cells during angiogenesis. J Biol Chem 286: 41095-41104. doi: 10.1074/jbc.M111.296806 PMID: 21937427
    • (2011) J Biol Chem , vol.286 , pp. 41095-41104
    • Wang, Y.1    Li, Z.2    Xu, P.3    Huang, L.4    Tong, J.5
  • 32
    • 34548591723 scopus 로고    scopus 로고
    • Berberine-induced LDLR up-regulation involves JNK pathway
    • PMID: 17767919
    • Lee S, Lim HJ, Park JH, Lee KS, Jang Y, et al. (2007) Berberine-induced LDLR up-regulation involves JNK pathway. Biochem Biophys Res Commun 362: 853-857. PMID: 17767919
    • (2007) Biochem Biophys Res Commun , vol.362 , pp. 853-857
    • Lee, S.1    Lim, H.J.2    Park, J.H.3    Lee, K.S.4    Jang, Y.5
  • 33
    • 84860324785 scopus 로고    scopus 로고
    • MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1
    • PMID: 22465663
    • Wang L, Shi M, Hou S, Ding B, Liu L, et al. (2012) MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1. FEBS Lett 586: 1312-1317. doi: 10.1016/j.febslet.2012.03.035 PMID: 22465663
    • (2012) FEBS Lett , vol.586 , pp. 1312-1317
    • Wang, L.1    Shi, M.2    Hou, S.3    Ding, B.4    Liu, L.5
  • 34
    • 84865093689 scopus 로고    scopus 로고
    • MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN
    • PMID: 22885155
    • Liu B, Wu X, Wang C, Liu Y, Zhou Q, et al. (2012) MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN. Biochim Biophys Acta 1822: 1692-1704. doi: 10.1016/j.bbadis.2012.07.019 PMID: 22885155
    • (2012) Biochim Biophys Acta , vol.1822 , pp. 1692-1704
    • Liu, B.1    Wu, X.2    Wang, C.3    Liu, Y.4    Zhou, Q.5
  • 36
    • 84890018024 scopus 로고    scopus 로고
    • Exploration of genome-wide circulating microRNA in hepatocellular carcinoma: MiR-483-5p as a potential biomarker
    • PMID: 24127413
    • Shen J, Wang A, Wang Q, Gurvich I, Siegel AB, et al. (2013) Exploration of genome-wide circulating microRNA in hepatocellular carcinoma: MiR-483-5p as a potential biomarker. Cancer Epidemiol Biomarkers Prev 22: 2364-2373. doi: 10.1158/1055-9965.EPI-13-0237 PMID: 24127413
    • (2013) Cancer Epidemiol Biomarkers Prev , vol.22 , pp. 2364-2373
    • Shen, J.1    Wang, A.2    Wang, Q.3    Gurvich, I.4    Siegel, A.B.5
  • 37
    • 84866364068 scopus 로고    scopus 로고
    • The rectal cancer microRNAome - microRNA expression in rectal cancer and matched normal mucosa
    • PMID: 22850566
    • Gaedcke J, Grade M, Camps J, Sokilde R, Kaczkowski B, et al. (2012) The rectal cancer microRNAome - microRNA expression in rectal cancer and matched normal mucosa. Clin Cancer Res 18: 4919-4930. PMID: 22850566
    • (2012) Clin Cancer Res , vol.18 , pp. 4919-4930
    • Gaedcke, J.1    Grade, M.2    Camps, J.3    Sokilde, R.4    Kaczkowski, B.5
  • 38
    • 84923320617 scopus 로고    scopus 로고
    • MicroRNA as a Modulator of Cell Proliferation and Senescence: Role in Lung Cancer Cells
    • Hayat MA, editor Aging, Cancer, and Noncancer Pathologies: Springer
    • Fukui S, Sekiguchi M, Miyata K, Ohdaira H, Yoshia K (2013) MicroRNA as a Modulator of Cell Proliferation and Senescence: Role in Lung Cancer Cells. In: Hayat MA, editor. Tumor Dormancy, Quiescence, and Senescence, Volume 1: Aging, Cancer, and Noncancer Pathologies: Springer. pp. 270-279.
    • (2013) Tumor Dormancy, Quiescence, and Senescence , vol.1 , pp. 270-279
    • Fukui, S.1    Sekiguchi, M.2    Miyata, K.3    Ohdaira, H.4    Yoshia, K.5
  • 39
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • PMID: 15944708
    • Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838. PMID: 15944708
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3    Alvarez-Saavedra, E.4    Lamb, J.5
  • 40
    • 84888107536 scopus 로고    scopus 로고
    • MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis
    • PMID: 24158479
    • Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, et al. (2013) MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proc Natl Acad Sci U S A 110: 18946-18951. doi: 10.1073/pnas.1220319110 PMID: 24158479
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 18946-18951
    • Perdomo, C.1    Campbell, J.D.2    Gerrein, J.3    Tellez, C.S.4    Garrison, C.B.5
  • 41
    • 59649093464 scopus 로고    scopus 로고
    • Evolution of microRNA expression during human bronchial squamous carcinogenesis
    • PMID: 19010987
    • Mascaux C, Laes JF, Anthoine G, Haller A, Ninane V, et al. (2009) Evolution of microRNA expression during human bronchial squamous carcinogenesis. Eur Respir J 33: 352-359. doi: 10.1183/09031936.00084108 PMID: 19010987
    • (2009) Eur Respir J , vol.33 , pp. 352-359
    • Mascaux, C.1    Laes, J.F.2    Anthoine, G.3    Haller, A.4    Ninane, V.5
  • 42
    • 84872707487 scopus 로고    scopus 로고
    • Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer
    • Gomperts BN, Walser TC, Spira A, Dubinett SM (2013) Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer. Cancer Prev Res (Phila) 6: 4-7.
    • (2013) Cancer Prev Res (Phila) , vol.6 , pp. 4-7
    • Gomperts, B.N.1    Walser, T.C.2    Spira, A.3    Dubinett, S.M.4
  • 43
    • 34248563290 scopus 로고    scopus 로고
    • The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
    • PMID: 17496918
    • Meloche S, Pouyssegur J (2007) The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 26: 3227-3239. PMID: 17496918
    • (2007) Oncogene , vol.26 , pp. 3227-3239
    • Meloche, S.1    Pouyssegur, J.2
  • 44
    • 84891754004 scopus 로고    scopus 로고
    • Erk/MAP Kinase Signaling Pathway and Neuroendocrine Differentiation of Non-Small-Cell Lung Cancer
    • PMID: 24346093
    • Chen Y, Nowak I, Huang J, Keng PC, Sun H, et al. (2014) Erk/MAP Kinase Signaling Pathway and Neuroendocrine Differentiation of Non-Small-Cell Lung Cancer. J Thorac Oncol 9: 50-58. doi: 10.1097/JTO.0000000000000034 PMID: 24346093
    • (2014) J Thorac Oncol , vol.9 , pp. 50-58
    • Chen, Y.1    Nowak, I.2    Huang, J.3    Keng, P.C.4    Sun, H.5
  • 45
    • 1942521000 scopus 로고    scopus 로고
    • ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours
    • PMID: 14997206
    • Vicent S, Lopez-Picazo JM, Toledo G, Lozano MD, Torre W, et al. (2004) ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours. Br J Cancer 90: 1047-1052. PMID: 14997206
    • (2004) Br J Cancer , vol.90 , pp. 1047-1052
    • Vicent, S.1    Lopez-Picazo, J.M.2    Toledo, G.3    Lozano, M.D.4    Torre, W.5
  • 47
    • 34247357465 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells
    • PMID: 17057737
    • Khatlani TS, Wislez M, Sun M, Srinivas H, Iwanaga K, et al. (2007) c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells. Oncogene 26: 2658-2666. PMID: 17057737
    • (2007) Oncogene , vol.26 , pp. 2658-2666
    • Khatlani, T.S.1    Wislez, M.2    Sun, M.3    Srinivas, H.4    Iwanaga, K.5
  • 49
    • 84884673317 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-mediated suppression of dual-specificity phosphatase 4: Crosstalk between NFkappaB and MAPK regulates endothelial cell survival
    • PMID: 23812841
    • Kao DD, Oldebeken SR, Rai A, Lubos E, Leopold JA, et al. (2013) Tumor necrosis factor-alpha-mediated suppression of dual-specificity phosphatase 4: crosstalk between NFkappaB and MAPK regulates endothelial cell survival. Mol Cell Biochem 382: 153-162. doi: 10.1007/s11010-013-1730-7 PMID: 23812841
    • (2013) Mol Cell Biochem , vol.382 , pp. 153-162
    • Kao, D.D.1    Oldebeken, S.R.2    Rai, A.3    Lubos, E.4    Leopold, J.A.5
  • 50
    • 0038521284 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells
    • PMID: 12594228
    • Pirola L, Bonnafous S, Johnston AM, Chaussade C, Portis F, et al. (2003) Phosphoinositide 3-kinase-mediated reduction of insulin receptor substrate-1/2 protein expression via different mechanisms contributes to the insulin-induced desensitization of its signaling pathways in L6 muscle cells. J Biol Chem 278: 15641-15651. PMID: 12594228
    • (2003) J Biol Chem , vol.278 , pp. 15641-15651
    • Pirola, L.1    Bonnafous, S.2    Johnston, A.M.3    Chaussade, C.4    Portis, F.5
  • 51
    • 84872729139 scopus 로고    scopus 로고
    • Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling
    • Kadara H, Shen L, Fujimoto J, Saintigny P, Chow CW, et al. (2013) Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling. Cancer Prev Res (Phila) 6: 8-17.
    • (2013) Cancer Prev Res (Phila) , vol.6 , pp. 8-17
    • Kadara, H.1    Shen, L.2    Fujimoto, J.3    Saintigny, P.4    Chow, C.W.5
  • 52
    • 84898717571 scopus 로고    scopus 로고
    • Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer
    • PMID: 24563515
    • Kadara H, Fujimoto J, Yoo SY, Maki Y, Gower AC, et al. (2014) Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer. J Natl Cancer Inst 106: dju004. doi: 10.1093/jnci/dju004 PMID: 24563515
    • (2014) J Natl Cancer Inst , vol.106 , pp. dju004
    • Kadara, H.1    Fujimoto, J.2    Yoo, S.Y.3    Maki, Y.4    Gower, A.C.5
  • 53
    • 77952987104 scopus 로고    scopus 로고
    • Airway PI3K pathway activation is an early and reversible event in lung cancer development
    • PMID: 20375364
    • Gustafson AM, Soldi R, Anderlind C, Scholand MB, Qian J, et al. (2010) Airway PI3K pathway activation is an early and reversible event in lung cancer development. Sci Transl Med 2: 26ra25. doi: 10.1126/scitranslmed.3000251 PMID: 20375364
    • (2010) Sci Transl Med , vol.2 , pp. 26ra25
    • Gustafson, A.M.1    Soldi, R.2    Anderlind, C.3    Scholand, M.B.4    Qian, J.5
  • 55
    • 84861726425 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase (DPD) expression is negatively regulated by certain microRNAs in human lung tissues
    • PMID: 22306127
    • Hirota T, Date Y, Nishibatake Y, Takane H, Fukuoka Y, et al. (2012) Dihydropyrimidine dehydrogenase (DPD) expression is negatively regulated by certain microRNAs in human lung tissues. Lung Cancer 77: 16-23. doi: 10.1016/j.lungcan.2011.12.018 PMID: 22306127
    • (2012) Lung Cancer , vol.77 , pp. 16-23
    • Hirota, T.1    Date, Y.2    Nishibatake, Y.3    Takane, H.4    Fukuoka, Y.5
  • 56
    • 84895058767 scopus 로고    scopus 로고
    • Human ERV3-1 env protein expression in various human tissues and tumours
    • PMID: 24043713
    • Kang YJ, Jo JO, Ock MS, Chang HK, Baek KW, et al. (2014) Human ERV3-1 env protein expression in various human tissues and tumours. J Clin Pathol 67: 86-90. doi: 10.1136/jclinpath-2013-201841 PMID: 24043713
    • (2014) J Clin Pathol , vol.67 , pp. 86-90
    • Kang, Y.J.1    Jo, J.O.2    Ock, M.S.3    Chang, H.K.4    Baek, K.W.5
  • 57
    • 0027484740 scopus 로고
    • Evidence for up-regulated low density lipoprotein receptor in human lung adenocarcinoma cell line A549
    • PMID: 8274533
    • Gueddari N, Favre G, Hachem H, Marek E, Le Gaillard F, et al. (1993) Evidence for up-regulated low density lipoprotein receptor in human lung adenocarcinoma cell line A549. Biochimie 75: 811-819. PMID: 8274533
    • (1993) Biochimie , vol.75 , pp. 811-819
    • Gueddari, N.1    Favre, G.2    Hachem, H.3    Marek, E.4    Le Gaillard, F.5
  • 58
    • 40749138663 scopus 로고    scopus 로고
    • Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer
    • PMID: 18172250
    • Prudkin L, Behrens C, Liu DD, Zhou X, Ozburn NC, et al. (2008) Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer. Clin Cancer Res 14: 41-47. doi: 10.1158/1078-0432.CCR-07-1252 PMID: 18172250
    • (2008) Clin Cancer Res , vol.14 , pp. 41-47
    • Prudkin, L.1    Behrens, C.2    Liu, D.D.3    Zhou, X.4    Ozburn, N.C.5
  • 59
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • PMID: 16530703
    • Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, et al. (2006) Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9: 189-198. PMID: 16530703
    • (2006) Cancer Cell , vol.9 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3    Seike, M.4    Kumamoto, K.5
  • 60
    • 84860255370 scopus 로고    scopus 로고
    • MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells
    • PMID: 22469510
    • Dang X, Ma A, Yang L, Hu H, Zhu B, et al. (2012) MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells. Cancer Genet 205: 113-123. doi: 10.1016/j.cancergen.2012.01.002 PMID: 22469510
    • (2012) Cancer Genet , vol.205 , pp. 113-123
    • Dang, X.1    Ma, A.2    Yang, L.3    Hu, H.4    Zhu, B.5
  • 61
    • 84902157182 scopus 로고    scopus 로고
    • miR-483-5p promotes invasion and metastasis of lung adenocarcinoma by targeting RhoGDI1 and ALCAM
    • PMID: 24710410
    • Song Q, Xu Y, Yang C, Chen Z, Jia C, et al. (2014) miR-483-5p promotes invasion and metastasis of lung adenocarcinoma by targeting RhoGDI1 and ALCAM. Cancer Res 74: 3031-3042. doi: 10.1158/0008-5472.CAN-13-2193 PMID: 24710410
    • (2014) Cancer Res , vol.74 , pp. 3031-3042
    • Song, Q.1    Xu, Y.2    Yang, C.3    Chen, Z.4    Jia, C.5
  • 63
    • 84863325324 scopus 로고    scopus 로고
    • Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers
    • PMID: 22573352
    • Jang JS, Jeon HS, Sun Z, Aubry MC, Tang H, et al. (2012) Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers. Clin Cancer Res 18: 3658-3667. doi: 10.1158/1078-0432.CCR-11-2857 PMID: 22573352
    • (2012) Clin Cancer Res , vol.18 , pp. 3658-3667
    • Jang, J.S.1    Jeon, H.S.2    Sun, Z.3    Aubry, M.C.4    Tang, H.5
  • 64
    • 84858287854 scopus 로고    scopus 로고
    • Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells
    • PMID: 22301433
    • Hua S, Xiaotao X, Renhua G, Yongmei Y, Lianke L, et al. (2012) Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. Biomed Pharmacother 66: 89-97. doi: 10.1016/j.biopha.2011.09.013 PMID: 22301433
    • (2012) Biomed Pharmacother , vol.66 , pp. 89-97
    • Hua, S.1    Xiaotao, X.2    Renhua, G.3    Yongmei, Y.4    Lianke, L.5
  • 65
    • 84904680624 scopus 로고    scopus 로고
    • ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation
    • PMID: 24037524
    • Kosari F, Ida CM, Aubry MC, Yang L, Kovtun IV, et al. (2014) ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation. Oncogene 33: 3776-3783. doi: 10.1038/onc.2013.359 PMID: 24037524
    • (2014) Oncogene , vol.33 , pp. 3776-3783
    • Kosari, F.1    Ida, C.M.2    Aubry, M.C.3    Yang, L.4    Kovtun, I.V.5
  • 66
    • 84922008002 scopus 로고    scopus 로고
    • Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease
    • PMID: 25317467
    • Staudt MR, Buro-Auriemma LJ, Walters MS, Salit J, Vincent T, et al. (2014) Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 190: 955-958. doi: 10.1164/rccm.201406-1167LE PMID: 25317467
    • (2014) Am J Respir Crit Care Med , vol.190 , pp. 955-958
    • Staudt, M.R.1    Buro-Auriemma, L.J.2    Walters, M.S.3    Salit, J.4    Vincent, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.