The transport and efflux of glycosylated luteinising hormone-releasing hormone analogues in Caco-2 cell model: Contributions of glucose transporters and efflux systems

Journal of Pharmaceutical Sciences

Volumn 103, Issue 10, 2014, Pages 3217-3224

  Moradi, Shayli Varasteh ^a   Varamini, Pegah ^a   Toth, Istvan ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Caco 2 cell; Efflux pumps; GLUT2; Glycosylation; LHRH; MRP2; P glycoprotein; Peptides; SGLT1; Transport

Indexed keywords

ABC TRANSPORTER; GLUCOSE TRANSPORTER 2; GLYCOSYLATED PROTEIN; GONADORELIN DERIVATIVE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; PHLORETIN; PHLORIZIN; SODIUM GLUCOSE COTRANSPORTER 1; VERAPAMIL; VERLUKAST; GLUCOSE; GONADORELIN;

AMINO ACID SEQUENCE; ARTICLE; CACO 2 CELL LINE; CELL MEMBRANE PERMEABILITY; CELL TRANSPORT; CONTROLLED STUDY; DRUG PENETRATION; DRUG PURIFICATION; DRUG SYNTHESIS; DRUG TRANSPORT; GLYCOSYLATION; HEXOSE TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; SUGAR TRANSPORT; BIOLOGICAL MODEL; ELECTROSPRAY MASS SPECTROMETRY; METABOLISM; ULTRAVIOLET SPECTROPHOTOMETRY;

CACO-2 CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCOSE; GLYCOSYLATION; GONADOTROPIN-RELEASING HORMONE; HUMANS; MODELS, BIOLOGICAL; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84923376858     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24120     Document Type: Article

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