Rapamycin improves sociability in the BTBR T+Itpr3tf/J mouse model of autism spectrum disorders

Brain Research Bulletin

Volumn 100, Issue , 2014, Pages 70-75

  Burket, Jessica A ^a   Benson, Andrew D ^a   Tang, Amy H ^a   Deutsch, Stephen I ^a,b  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b Department of Psychiatry and Behavioral Sciences   (United States)

Author keywords

BTBR mice; MTOR signaling; NMDA receptor; Rapamycin; Sociability

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; CONTROLLED STUDY; DRUG TARGETING; LOCOMOTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REARING; SOCIAL BEHAVIOR; SOCIALIZATION; STEREOTYPY; STIMULUS; TREATMENT DURATION;

BTBR MICE; MTOR SIGNALING; NMDA RECEPTOR; RAPAMYCIN; SOCIABILITY;

ANIMALS; BEHAVIOR, ANIMAL; CHILD DEVELOPMENT DISORDERS, PERVASIVE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; MALE; MICE; MICE, MUTANT STRAINS; MULTIPROTEIN COMPLEXES; SIROLIMUS; SOCIAL BEHAVIOR; STEREOTYPED BEHAVIOR; TOR SERINE-THREONINE KINASES;

EID: 84890811053     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2013.11.005     Document Type: Article

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