-
1
-
-
26844574658
-
Runx2: A master organizer of gene transcription in developing and maturing osteoblasts
-
Schroeder, T. M., Jensen, E. D. & Westendorf, J. J. Runx2: a master organizer of gene transcription in developing and maturing osteoblasts. Birth Defects Res. C Embryo Today 75, 213-225 (2005).
-
(2005)
Birth Defects Res. C Embryo Today
, vol.75
, pp. 213-225
-
-
Schroeder, T.M.1
Jensen, E.D.2
Westendorf, J.J.3
-
2
-
-
37249028142
-
Transcriptional regulation of osteoblasts
-
Franceschi, R. T., Ge, C., Xiao, G., Roca, H. & Jiang, D. Transcriptional regulation of osteoblasts. Ann. N. Y. Acad. Sci. 1116, 196-207 (2007).
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1116
, pp. 196-207
-
-
Franceschi, R.T.1
Ge, C.2
Xiao, G.3
Roca, H.4
Jiang, D.5
-
3
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
-
Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L. & Karsenty, G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89, 747-754 (1997).
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
4
-
-
72449129934
-
Regulation of bone development and extracellular matrix protein genes by RUNX2
-
Komori, T. Regulation of bone development and extracellular matrix protein genes by RUNX2. Cell Tissue Res. 339, 189-195 (2010).
-
(2010)
Cell Tissue Res.
, vol.339
, pp. 189-195
-
-
Komori, T.1
-
5
-
-
79951792447
-
Signaling networks in RUNX2-dependent bone development
-
Komori, T. Signaling networks in RUNX2-dependent bone development. J. Cell Biochem. 112, 750-755 (2011).
-
(2011)
J. Cell Biochem.
, vol.112
, pp. 750-755
-
-
Komori, T.1
-
6
-
-
84255200563
-
Building strong bones: Molecular regulation of the osteoblast lineage
-
Long, F. Building strong bones: molecular regulation of the osteoblast lineage. Nat. Rev. Mol. Cell Biol. 13, 27-38 (2012).
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 27-38
-
-
Long, F.1
-
7
-
-
70349342805
-
Post-translational regulation of Runx2 in bone and cartilage
-
Jonason, J. H., Xiao, G., Zhang, M., Xing, L. & Chen, D. Post-translational regulation of Runx2 in bone and cartilage. J. Dent. Res. 88, 693-703 (2009).
-
(2009)
J. Dent. Res.
, vol.88
, pp. 693-703
-
-
Jonason, J.H.1
Xiao, G.2
Zhang, M.3
Xing, L.4
Chen, D.5
-
8
-
-
0037405123
-
Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity
-
Sierra, J. et al. Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity. Mol. Cell Biol. 23, 3339-3351 (2003).
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 3339-3351
-
-
Sierra, J.1
-
9
-
-
0034916613
-
P300/CBP proteins: HATs for transcriptional bridges and scaffolds
-
Chan, H. M. & La Thangue, N. B. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J. Cell Sci. 114, 2363-2373 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2363-2373
-
-
Chan, H.M.1
La Thangue, N.B.2
-
10
-
-
33745196250
-
Bone morphogenetic protein-2 stimulates Runx2 acetylation
-
Jeon, E. J. et al. Bone morphogenetic protein-2 stimulates Runx2 acetylation. J. Biol. Chem. 281, 16502-16511 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16502-16511
-
-
Jeon, E.J.1
-
11
-
-
78449244722
-
BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activity
-
Jun, J. H. et al. BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activity. J. Biol. Chem. 285, 36410-36419 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 36410-36419
-
-
Jun, J.H.1
-
12
-
-
0041845297
-
E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation and plays a specific role in osteoblast differentiation
-
Zhao, M., Qiao, M., Oyajobi, B. O., Mundy, G. R. & Chen, D. E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation and plays a specific role in osteoblast differentiation. J. Biol. Chem. 278, 27939-27944 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27939-27944
-
-
Zhao, M.1
Qiao, M.2
Oyajobi, B.O.3
Mundy, G.R.4
Chen, D.5
-
13
-
-
0037129340
-
MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2
-
Pelletier, N., Champagne, N., Stifani, S. & Yang, X. J. MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2. Oncogene 21, 2729-2740 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 2729-2740
-
-
Pelletier, N.1
Champagne, N.2
Stifani, S.3
Yang, X.J.4
-
14
-
-
0022407123
-
The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways
-
Whiteway, M. & Szostak, J. W. The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways. Cell 43, 483-492 (1985).
-
(1985)
Cell
, vol.43
, pp. 483-492
-
-
Whiteway, M.1
Szostak, J.W.2
-
15
-
-
20544431636
-
Analysis of ARD1 function in hypoxia response using retroviral RNA interference
-
Fisher, T. S., Etages, S. D., Hayes, L., Crimin, K. & Li, B. Analysis of ARD1 function in hypoxia response using retroviral RNA interference. J. Biol. Chem. 280, 17749-17757 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17749-17757
-
-
Fisher, T.S.1
Etages, S.D.2
Hayes, L.3
Crimin, K.4
Li, B.5
-
16
-
-
66249126298
-
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
-
Arnesen, T. et al. Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans. Proc. Natl Acad. Sci. USA 106, 8157-8162 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 8157-8162
-
-
Arnesen, T.1
-
17
-
-
33845293454
-
Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation
-
Lim, J. H., Park, J. W. & Chun, Y. S. Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation. Cancer Res. 66, 10677-10682 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 10677-10682
-
-
Lim, J.H.1
Park, J.W.2
Chun, Y.S.3
-
18
-
-
70449379394
-
Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase
-
Shin, D. H., Chun, Y. S., Lee, K. H., Shin, H. W. & Park, J. W. Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase. PLoS ONE 4, e7451 (2009).
-
(2009)
PLoS ONE
, vol.4
, pp. e7451
-
-
Shin, D.H.1
Chun, Y.S.2
Lee, K.H.3
Shin, H.W.4
Park, J.W.5
-
19
-
-
84863180026
-
Inactivation of androgen-induced regulator ARD1 inhibits androgen receptor acetylation and prostate tumorigenesis
-
Wang, Z. et al. Inactivation of androgen-induced regulator ARD1 inhibits androgen receptor acetylation and prostate tumorigenesis. Proc. Natl Acad. Sci. USA 109, 3053-3058 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 3053-3058
-
-
Wang, Z.1
-
20
-
-
84155188831
-
Update on Wnt signaling in bone cell biology and bone disease
-
Monroe, D. G., McGee-Lawrence, M. E., Oursler, M. J. & Westendorf, J. J. Update on Wnt signaling in bone cell biology and bone disease. Gene 492, 1-18 (2012).
-
(2012)
Gene
, vol.492
, pp. 1-18
-
-
Monroe, D.G.1
McGee-Lawrence, M.E.2
Oursler, M.J.3
Westendorf, J.J.4
-
21
-
-
84858200481
-
Regulation of bone and cartilage development by network between BMP signalling and transcription factors
-
Nishimura, R., Hata, K., Matsubara, T., Wakabayashi, M. & Yoneda, T. Regulation of bone and cartilage development by network between BMP signalling and transcription factors. J. Biochem. 151, 247-254 (2012).
-
(2012)
J. Biochem.
, vol.151
, pp. 247-254
-
-
Nishimura, R.1
Hata, K.2
Matsubara, T.3
Wakabayashi, M.4
Yoneda, T.5
-
22
-
-
70349140915
-
Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation
-
Kuo, H. P. et al. Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation. Biochem. Biophys. Res. Commun. 389, 156-161 (2009).
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.389
, pp. 156-161
-
-
Kuo, H.P.1
-
23
-
-
30344475845
-
Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2
-
Pockwinse, S. M. et al. Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2. J. Cell. Physiol. 206, 354-362 (2006).
-
(2006)
J. Cell. Physiol.
, vol.206
, pp. 354-362
-
-
Pockwinse, S.M.1
-
24
-
-
0024461828
-
Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast
-
Mullen, J. R. et al. Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast. EMBO J. 8, 2067-2075 (1989).
-
(1989)
EMBO J.
, vol.8
, pp. 2067-2075
-
-
Mullen, J.R.1
-
25
-
-
54449090774
-
N-acetyltransferase ARD1-NAT1 regulates neuronal dendritic development
-
Ohkawa, N. et al. N-acetyltransferase ARD1-NAT1 regulates neuronal dendritic development. Genes Cells 13, 1171-1183 (2008).
-
(2008)
Genes Cells
, vol.13
, pp. 1171-1183
-
-
Ohkawa, N.1
-
26
-
-
0141925607
-
An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development
-
Sugiura, N., Adams, S. M. & Corriveau, R. A. An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development. J. Biol. Chem. 278, 40113-40120 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40113-40120
-
-
Sugiura, N.1
Adams, S.M.2
Corriveau, R.A.3
-
27
-
-
33751197049
-
Regulation of osteoblast differentiation by transcription factors
-
Komori, T. Regulation of osteoblast differentiation by transcription factors. J. Cell. Biochem. 99, 1233-1239 (2006).
-
(2006)
J. Cell. Biochem.
, vol.99
, pp. 1233-1239
-
-
Komori, T.1
-
28
-
-
0036333736
-
High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage
-
Geoffroy, V., Kneissel, M., Fournier, B., Boyde, A. & Matthias, P. High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage. Mol. Cell Biol. 22, 6222-6233 (2002).
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 6222-6233
-
-
Geoffroy, V.1
Kneissel, M.2
Fournier, B.3
Boyde, A.4
Matthias, P.5
-
29
-
-
84883743838
-
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex
-
Liszczak, G. et al. Molecular basis for N-terminal acetylation by the heterodimeric NatA complex. Nat. Struct. Mol. Biol. 20, 1098-1105 (2013).
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1098-1105
-
-
Liszczak, G.1
-
30
-
-
79955761504
-
Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase
-
M110.004580
-
Van Damme, P. et al. Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase. Mol. Cell. Proteomics 10, M110.004580 (2011).
-
(2011)
Mol. Cell. Proteomics
, vol.10
-
-
Van Damme, P.1
-
31
-
-
0037020149
-
Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex
-
Willis, D. M. et al. Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex. J. Biol. Chem. 277, 37280-37291 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37280-37291
-
-
Willis, D.M.1
-
32
-
-
84860385177
-
Runx2 protein stabilizes hypoxia-inducible factor-1alpha through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes
-
Lee, S. H. et al. Runx2 protein stabilizes hypoxia-inducible factor-1alpha through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes. J. Biol. Chem. 287, 14760-14771 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 14760-14771
-
-
Lee, S.H.1
-
33
-
-
32044468546
-
Phosphorylation, acetylation and ubiquitination: The molecular basis of RUNX regulation
-
Bae, S. C. & Lee, Y. H. Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation. Gene 366, 58-66 (2006).
-
(2006)
Gene
, vol.366
, pp. 58-66
-
-
Bae, S.C.1
Lee, Y.H.2
-
34
-
-
18344372018
-
The RUNX genes: Gain or loss of function in cancer
-
Blyth, K., Cameron, E. R. & Neil, J. C. The RUNX genes: gain or loss of function in cancer. Nat. Rev. Cancer 5, 376-387 (2005).
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 376-387
-
-
Blyth, K.1
Cameron, E.R.2
Neil, J.C.3
-
35
-
-
18744362426
-
Cbfbeta interacts with Runx2 and has a critical role in bone development
-
Kundu, M. et al. Cbfbeta interacts with Runx2 and has a critical role in bone development. Nat. Genet. 32, 639-644 (2002).
-
(2002)
Nat. Genet.
, vol.32
, pp. 639-644
-
-
Kundu, M.1
-
36
-
-
33745959553
-
Cbf beta regulates Runx2 function isoform-dependently in postnatal bone development
-
Kanatani, N. et al. Cbf beta regulates Runx2 function isoform-dependently in postnatal bone development. Dev. Biol. 296, 48-61 (2006).
-
(2006)
Dev. Biol.
, vol.296
, pp. 48-61
-
-
Kanatani, N.1
-
37
-
-
78649761287
-
Low-level laser irradiation enhances BMP-induced osteoblast differentiation by stimulating the BMP/Smad signaling pathway
-
Hirata, S. et al. Low-level laser irradiation enhances BMP-induced osteoblast differentiation by stimulating the BMP/Smad signaling pathway. J. Cell Biochem. 111, 1445-1452 (2010).
-
(2010)
J. Cell Biochem.
, vol.111
, pp. 1445-1452
-
-
Hirata, S.1
-
38
-
-
27644494876
-
Smad transcription factors
-
Massague, J., Seoane, J. & Wotton, D. Smad transcription factors. Gene Dev. 19, 2783-2810 (2005).
-
(2005)
Gene Dev.
, vol.19
, pp. 2783-2810
-
-
Massague, J.1
Seoane, J.2
Wotton, D.3
-
39
-
-
36348967117
-
A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft)
-
McKay, W. F., Peckham, S. M. & Badura, J. M. A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft). Int. Orthop. 31, 729-734 (2007).
-
(2007)
Int. Orthop.
, vol.31
, pp. 729-734
-
-
McKay, W.F.1
Peckham, S.M.2
Badura, J.M.3
-
40
-
-
0036899744
-
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: A prospective, controlled, randomized study of four hundred and fifty patients
-
Govender, S. et al. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J. Bone Joint Surg. Am. 84-A, 2123-2134 (2002).
-
(2002)
J. Bone Joint Surg. Am.
, vol.84-A
, pp. 2123-2134
-
-
Govender, S.1
-
41
-
-
27744503046
-
Clinical applications of BMP-7: The UK perspective
-
Giannoudis, P. V. & Tzioupis, C. Clinical applications of BMP-7: the UK perspective. Injury 36(Suppl 3): S47-S50 (2005).
-
(2005)
Injury
, vol.36
, pp. S47-S50
-
-
Giannoudis, P.V.1
Tzioupis, C.2
-
42
-
-
77949943221
-
Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1alpha in tumor growth and metastasis
-
Lee, M. N. et al. Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1alpha in tumor growth and metastasis. J. Natl. Cancer Inst. 102, 426-442 (2010).
-
(2010)
J. Natl. Cancer Inst.
, vol.102
, pp. 426-442
-
-
Lee, M.N.1
|