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Volumn 63, Issue 1, 2010, Pages 31-39

A toxin-antitoxin module as a target for antimicrobial development

Author keywords

Antimicrobials; BRET; Molecular dynamics; Toxin antitoxin modules

Indexed keywords

AMPICILLIN; ANTITOXIN; ASPARTIC ACID; BACTERIAL TOXIN; CIPROFLOXACIN; ERYTHROMYCIN; GLUTAMIC ACID; GREEN FLUORESCENT PROTEIN;

EID: 73049085016     PISSN: 0147619X     EISSN: 10959890     Source Type: Journal    
DOI: 10.1016/j.plasmid.2009.09.005     Document Type: Article
Times cited : (63)

References (31)
  • 2
    • 10044283095 scopus 로고    scopus 로고
    • MazF-mediated cell death in Escherichia coli: a point of no return
    • Amitai S., et al. MazF-mediated cell death in Escherichia coli: a point of no return. J. Bacteriol. 186 (2004) 8295-8300
    • (2004) J. Bacteriol. , vol.186 , pp. 8295-8300
    • Amitai, S.1
  • 3
    • 4644343922 scopus 로고    scopus 로고
    • Bacterial persistence as a phenotypic switch
    • Balaban N.Q., et al. Bacterial persistence as a phenotypic switch. Science 305 (2004) 1622-1625
    • (2004) Science , vol.305 , pp. 1622-1625
    • Balaban, N.Q.1
  • 4
    • 0345827436 scopus 로고    scopus 로고
    • SOS response promotes horizontal dissemination of antibiotic resistance genes
    • Beaber J.W., et al. SOS response promotes horizontal dissemination of antibiotic resistance genes. Nature 427 (2004) 72-74
    • (2004) Nature , vol.427 , pp. 72-74
    • Beaber, J.W.1
  • 5
    • 0033591287 scopus 로고    scopus 로고
    • Emerging infectious diseases: public health issues for the 21st century
    • Binder S., et al. Emerging infectious diseases: public health issues for the 21st century. Science 284 (1999) 1311-1313
    • (1999) Science , vol.284 , pp. 1311-1313
    • Binder, S.1
  • 6
    • 0141988381 scopus 로고    scopus 로고
    • Identification of SNARE complex modulators that inhibit exocytosis from an α-helix-constrained combinatorial library
    • Blanes-Mira C., et al. Identification of SNARE complex modulators that inhibit exocytosis from an α-helix-constrained combinatorial library. Biochem. J. 375 (2003) 159-166
    • (2003) Biochem. J. , vol.375 , pp. 159-166
    • Blanes-Mira, C.1
  • 7
    • 27944437497 scopus 로고    scopus 로고
    • Toxin-antitoxin modules as bacterial metabolic stress managers
    • Buts L., et al. Toxin-antitoxin modules as bacterial metabolic stress managers. Trends Biochem. Sci. 30 (2005) 672-679
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 672-679
    • Buts, L.1
  • 8
    • 12244282678 scopus 로고    scopus 로고
    • 2 protein complex of the broad host-range Streptococcus pyogenes pSM19035 addiction system
    • 2 protein complex of the broad host-range Streptococcus pyogenes pSM19035 addiction system. Biol. Chem. 383 (2002) 1701-1713
    • (2002) Biol. Chem. , vol.383 , pp. 1701-1713
    • Camacho, A.G.1
  • 9
    • 3242769052 scopus 로고    scopus 로고
    • Fighting superbugs with superdrugs
    • Carey J. Fighting superbugs with superdrugs. Drug Discov. Today 9 (2004) 637-640
    • (2004) Drug Discov. Today , vol.9 , pp. 637-640
    • Carey, J.1
  • 10
    • 23444454552 scopus 로고    scopus 로고
    • The Amber biomolecular simulation programs
    • Case D.A., et al. The Amber biomolecular simulation programs. J. Comput. Chem. 26 (2005) 1668-1688
    • (2005) J. Comput. Chem. , vol.26 , pp. 1668-1688
    • Case, D.A.1
  • 11
    • 33750489399 scopus 로고    scopus 로고
    • Bacterial programmed cell death and multicellular behavior in bacteria
    • Engelberg-Kulka H., et al. Bacterial programmed cell death and multicellular behavior in bacteria. PLoS Genet. 2 (2006) e135
    • (2006) PLoS Genet. , vol.2
    • Engelberg-Kulka, H.1
  • 12
    • 17844370503 scopus 로고    scopus 로고
    • Prokaryotic toxin-antitoxin stress response loci
    • Gerdes K., et al. Prokaryotic toxin-antitoxin stress response loci. Nat. Rev. Microbiol. 3 (2005) 371-382
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 371-382
    • Gerdes, K.1
  • 13
    • 34547126009 scopus 로고    scopus 로고
    • Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae
    • Khoo S.K., et al. Molecular and structural characterization of the PezAT chromosomal toxin-antitoxin system of the human pathogen Streptococcus pneumoniae. J. Biol. Chem. 282 (2007) 19606-19618
    • (2007) J. Biol. Chem. , vol.282 , pp. 19606-19618
    • Khoo, S.K.1
  • 14
    • 35349019173 scopus 로고    scopus 로고
    • Invasive methicillin-resistant Staphylococcus aureus infections in the United States
    • Klevens R.M., et al. Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 298 (2007) 1763-1771
    • (2007) JAMA , vol.298 , pp. 1763-1771
    • Klevens, R.M.1
  • 15
    • 34548213103 scopus 로고    scopus 로고
    • A common mechanism of cellular death induced by bactericidal antibiotics
    • Kohanski M.A., et al. A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130 (2007) 797-810
    • (2007) Cell , vol.130 , pp. 797-810
    • Kohanski, M.A.1
  • 16
    • 58149151397 scopus 로고    scopus 로고
    • The communication factor EDF and the toxin-antitoxin module mazEF determine the mode of action of antibiotics
    • Kolodkin-Gal I., et al. The communication factor EDF and the toxin-antitoxin module mazEF determine the mode of action of antibiotics. PLoS Biol. 6 (2008) e319
    • (2008) PLoS Biol. , vol.6
    • Kolodkin-Gal, I.1
  • 17
    • 0037013426 scopus 로고    scopus 로고
    • Identification of novel antifungal nonapeptides through the screening of combinatorial peptide libraries based on a hexapeptide motif
    • Kundu B., et al. Identification of novel antifungal nonapeptides through the screening of combinatorial peptide libraries based on a hexapeptide motif. Bioorg. Med. Chem. Lett. 12 (2002) 1473-1476
    • (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 1473-1476
    • Kundu, B.1
  • 18
    • 7244250314 scopus 로고    scopus 로고
    • Antibiotics: a shot in the arm
    • Leeb M. Antibiotics: a shot in the arm. Nature 431 (2004) 892-893
    • (2004) Nature , vol.431 , pp. 892-893
    • Leeb, M.1
  • 19
    • 33747125700 scopus 로고    scopus 로고
    • pSM19035-encoded ζ toxin induces stasis followed by death in a subpopulation of cells
    • Lioy V.S., et al. pSM19035-encoded ζ toxin induces stasis followed by death in a subpopulation of cells. Microbiology 152 (2006) 2365-2379
    • (2006) Microbiology , vol.152 , pp. 2365-2379
    • Lioy, V.S.1
  • 21
    • 4644351908 scopus 로고    scopus 로고
    • SOS response induction by β-lactams and bacterial defense against antibiotic lethality
    • Miller C., et al. SOS response induction by β-lactams and bacterial defense against antibiotic lethality. Science 305 (2004) 1629-1631
    • (2004) Science , vol.305 , pp. 1629-1631
    • Miller, C.1
  • 22
    • 33645072739 scopus 로고    scopus 로고
    • The chromosomal relBE2 toxin-antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to detect toxin-antitoxin interaction
    • Nieto C., et al. The chromosomal relBE2 toxin-antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to detect toxin-antitoxin interaction. Mol. Microbiol. 59 (2006) 1280-1296
    • (2006) Mol. Microbiol. , vol.59 , pp. 1280-1296
    • Nieto, C.1
  • 23
    • 52249094198 scopus 로고    scopus 로고
    • Microbiology. Desperately seeking new antibiotics
    • Payne D.J. Microbiology. Desperately seeking new antibiotics. Science 321 (2008) 1644-1645
    • (2008) Science , vol.321 , pp. 1644-1645
    • Payne, D.J.1
  • 24
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: confronting the challenges of antibacterial discovery
    • Payne D.J., et al. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat. Rev. Drug Discov. 6 (2007) 29-40
    • (2007) Nat. Rev. Drug Discov. , vol.6 , pp. 29-40
    • Payne, D.J.1
  • 25
    • 0036067108 scopus 로고    scopus 로고
    • Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins
    • Pedersen K., et al. Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol. Microbiol. 45 (2002) 501-510
    • (2002) Mol. Microbiol. , vol.45 , pp. 501-510
    • Pedersen, K.1
  • 26
    • 0029836953 scopus 로고    scopus 로고
    • Discovering high-affinity ligands for proteins: SAR by NMR
    • Shuker S.B., et al. Discovering high-affinity ligands for proteins: SAR by NMR. Science 274 (1996) 1531-1534
    • (1996) Science , vol.274 , pp. 1531-1534
    • Shuker, S.B.1
  • 27
    • 47749093130 scopus 로고    scopus 로고
    • The bacteria fight back
    • Taubes G. The bacteria fight back. Science 321 (2008) 356-361
    • (2008) Science , vol.321 , pp. 356-361
    • Taubes, G.1
  • 28
    • 0003965498 scopus 로고    scopus 로고
    • Harwood Academic Publishers, Amsterdam p. 419
    • Thomas C.M. The Horizontal Gene Pool (2000), Harwood Academic Publishers, Amsterdam p. 419
    • (2000) The Horizontal Gene Pool
    • Thomas, C.M.1
  • 29
    • 32544456244 scopus 로고    scopus 로고
    • Antimicrobial peptides: new candidates in the fight against bacterial infections
    • Toke O. Antimicrobial peptides: new candidates in the fight against bacterial infections. Biopolymers 80 (2005) 717-735
    • (2005) Biopolymers , vol.80 , pp. 717-735
    • Toke, O.1
  • 30
    • 47649098600 scopus 로고    scopus 로고
    • Cooperativity and biological complexity
    • Whitty A. Cooperativity and biological complexity. Nat. Chem. Biol. 4 (2008) 435-439
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 435-439
    • Whitty, A.1
  • 31
    • 12244268639 scopus 로고    scopus 로고
    • Bioluminescence resonance energy transfer (BRET): a new technique for monitoring protein-protein interactions in living cells
    • Xu Y., et al. Bioluminescence resonance energy transfer (BRET): a new technique for monitoring protein-protein interactions in living cells. Methods Enzymol. 360 (2003) 289-301
    • (2003) Methods Enzymol. , vol.360 , pp. 289-301
    • Xu, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.