Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Dinter, Juliane ^a   Mühlhaus, Jessica ^a   Wienchol, Carolin Leonie ^a   Yi, Chun Xia ^b   Nürnberg, Daniela ^a   Morin, Silke ^b   Grüters, Annette ^a   Köhrle, Josef ^a   Schöneberg, Torsten ^c   Tschöp, Matthias ^a   Krude, Heiko ^a   Kleinau, Gunnar ^a   Biebermann, Heike ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 IODOTHYRONAMINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LEVOTHYROXINE; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; TRACE AMINE ASSOCIATED RECEPTOR 1; TRACE AMINE ASSOCIATED RECEPTOR 5; UNCLASSIFIED DRUG; 3-IODOTHYRONAMINE; TAAR5 PROTEIN, HUMAN; THYRONINE DERIVATIVE; TRACE AMINE-ASSOCIATED RECEPTOR 5, MOUSE;

AMYGDALOID NUCLEUS; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ZONA INCERTA; ANIMAL; C57BL MOUSE; CELL LINE; CHLOROCEBUS AETHIOPS; COS CELL LINE; DRUG EFFECTS; HEK293 CELL LINE; KNOCKOUT MOUSE; METABOLISM;

MAMMALIA; MURINAE; MUS; RODENTIA;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; HEK293 CELLS; HUMANS; LIGANDS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; THYRONINES;

EID: 84923325353     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0117774     Document Type: Article

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