An olfactory subsystem that mediates high-sensitivity detection of volatile amines

Cell Reports

Volumn 2, Issue 1, 2012, Pages 76-88

  Pacifico, Rodrigo ^a   Dewan, Adam ^a   Cawley, Dillon ^a   Guo, Caiying ^b   Bozza, Thomas ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; VOLATILE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; GENE; GENE EXPRESSION; GENE TARGETING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; OLFACTORY BULB; OLFACTORY EPITHELIUM; OLFACTORY RECEPTOR; OLFACTORY SYSTEM; SENSORY NERVE CELL; TRACE AMINE ASSOCIATED RECEPTOR GENE;

AMINES; ANIMALS; FEMALE; GENE TARGETING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MULTIGENE FAMILY; OLFACTORY PATHWAYS; OLFACTORY PERCEPTION; OLFACTORY RECEPTOR NEURONS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SUBSTRATE SPECIFICITY; VOLATILE ORGANIC COMPOUNDS; VOLATILIZATION;

MUS;

EID: 84864313337     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2012.06.006     Document Type: Article

References (53)

1. Adams D.J., Quail M.A., Cox T., van der Weyden L., Gorick B.D., Su Q., Chan W.I., Davies R., Bonfield J.K., Law F., et al. A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction. Genomics 2005, 86:753-758.
2. Borowsky B., Adham N., Jones K.A., Raddatz R., Artymyshyn R., Ogozalek K.L., Durkin M.M., Lakhlani P.P., Bonini J.A., Pathirana S., et al. Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc. Natl. Acad. Sci. USA 2001, 98:8966-8971.
3. Bozza T., Feinstein P., Zheng C., Mombaerts P. Odorant receptor expression defines functional units in the mouse olfactory system. J. Neurosci. 2002, 22:3033-3043.
4. Bozza T., McGann J.P., Mombaerts P., Wachowiak M. In vivo imaging of neuronal activity by targeted expression of a genetically encoded probe in the mouse. Neuron 2004, 42:9-21.
5. Bozza T., Vassalli A., Fuss S., Zhang J.J., Weiland B., Pacifico R., Feinstein P., Mombaerts P. Mapping of class I and class II odorant receptors to glomerular domains by two distinct types of olfactory sensory neurons in the mouse. Neuron 2009, 61:220-233.
6. Buck L., Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 1991, 65:175-187.
7. Bunzow J.R., Sonders M.S., Arttamangkul S., Harrison L.M., Zhang G., Quigley D.I., Darland T., Suchland K.L., Pasumamula S., Kennedy J.L., et al. Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor. Mol. Pharmacol. 2001, 60:1181-1188.
8. Chess A., Simon I., Cedar H., Axel R. Allelic inactivation regulates olfactory receptor gene expression. Cell 1994, 78:823-834.
9. Feinstein P., Mombaerts P. A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell 2004, 117:817-831.
10. Feinstein P., Bozza T., Rodriguez I., Vassalli A., Mombaerts P. Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor. Cell 2004, 117:833-846.
11. Ferrero D.M., Lemon J.K., Fluegge D., Pashkovski S.L., Korzan W.J., Datta S.R., Spehr M., Fendt M., Liberles S.D. Detection and avoidance of a carnivore odor by prey. Proc. Natl. Acad. Sci. USA 2011, 108:11235-11240.
12. Ferrero D.M., Wacker D., Roque M.A., Baldwin M.W., Stevens R.C., Liberles S.D. Agonists for 13 Trace Amine-Associated Receptors Provide Insight into the Molecular Basis of Odor Selectivity. ACS Chem. Biol. 2012.
13. Freitag J., Krieger J., Strotmann J., Breer H. Two classes of olfactory receptors in Xenopus laevis. Neuron 1995, 15:1383-1392.
14. Glusman G., Yanai I., Rubin I., Lancet D. The complete human olfactory subgenome. Genome Res. 2001, 11:685-702.
15. Grandy D.K. Trace amine-associated receptor 1-Family archetype or iconoclast?. Pharmacol. Ther. 2007, 116:355-390.
16. Hegg C.C., Lucero M.T. Purinergic receptor antagonists inhibit odorant-induced heat shock protein 25 induction in mouse olfactory epithelium. Glia 2006, 53:182-190.
17. Ishii T., Omura M., Mombaerts P. Protocols for two- and three-color fluorescent RNA in situ hybridization of the main and accessory olfactory epithelia in mouse. J. Neurocytol. 2004, 33:657-669.
18. Kobayakawa K., Kobayakawa R., Matsumoto H., Oka Y., Imai T., Ikawa M., Okabe M., Ikeda T., Itohara S., Kikusui T., et al. Innate versus learned odour processing in the mouse olfactory bulb. Nature 2007, 450:503-508.
19. Lewcock J.W., Reed R.R. A feedback mechanism regulates monoallelic odorant receptor expression. Proc. Natl. Acad. Sci. USA 2004, 101:1069-1074.
20. Liberles S.D. Trace amine-associated receptors are olfactory receptors in vertebrates. Ann. N Y Acad. Sci. 2009, 1170:168-172.
21. Liberles S.D., Buck L.B. A second class of chemosensory receptors in the olfactory epithelium. Nature 2006, 442:645-650.
22. Lindemann L., Ebeling M., Kratochwil N.A., Bunzow J.R., Grandy D.K., Hoener M.C. Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. Genomics 2005, 85:372-385.
23. Ma L., Qiu Q., Gradwohl S., Scott A., Yu E.Q., Alexander R., Wiegraebe W., Yu C.R. Distributed representation of chemical features and tunotopic organization of glomeruli in the mouse olfactory bulb. Proc. Natl. Acad. Sci. USA 2012, 109:5481-5486.
24. Malnic B., Hirono J., Sato T., Buck L.B. Combinatorial receptor codes for odors. Cell 1999, 96:713-723.
25. Matsumoto H., Kobayakawa K., Kobayakawa R., Tashiro T., Mori K., Sakano H., Mori K. Spatial arrangement of glomerular molecular-feature clusters in the odorant-receptor class domains of the mouse olfactory bulb. J. Neurophysiol. 2010, 103:3490-3500.
26. McGann J.P., Pírez N., Gainey M.A., Muratore C., Elias A.S., Wachowiak M. Odorant representations are modulated by intra- but not interglomerular presynaptic inhibition of olfactory sensory neurons. Neuron 2005, 48:1039-1053.
27. Mombaerts P., Wang F., Dulac C., Chao S.K., Nemes A., Mendelsohn M., Edmondson J., Axel R. Visualizing an olfactory sensory map. Cell 1996, 87:675-686.
28. Munger S.D., Leinders-Zufall T., Zufall F. Subsystem organization of the mammalian sense of smell. Annu. Rev. Physiol. 2009, 71:115-140.
29. Niimura Y. Evolutionary dynamics of olfactory receptor genes in chordates: interaction between environments and genomic contents. Hum. Genomics 2009, 4:107-118.
30. Ressler K.J., Sullivan S.L., Buck L.B. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 1994, 79:1245-1255.
31. Roppolo D., Vollery S., Kan C.D., Lüscher C., Broillet M.C., Rodriguez I. Gene cluster lock after pheromone receptor gene choice. EMBO J. 2007, 26:3423-3430.
32. Schoenfeld T.A., Cleland T.A. The anatomical logic of smell. Trends Neurosci. 2005, 28:620-627.
33. Serizawa S., Miyamichi K., Sakano H. One neuron-one receptor rule in the mouse olfactory system. Trends Genet. 2004, 20:648-653.
34. Serizawa S., Miyamichi K., Takeuchi H., Yamagishi Y., Suzuki M., Sakano H. A neuronal identity code for the odorant receptor-specific and activity-dependent axon sorting. Cell 2006, 127:1057-1069.
35. Silla Santos M.H. Biogenic amines: their importance in foods. Int. J. Food Microbiol. 1996, 29:213-231.
36. Soucy E.R., Albeanu D.F., Fantana A.L., Murthy V.N., Meister M. Precision and diversity in an odor map on the olfactory bulb. Nat. Neurosci. 2009, 12:210-220.
37. Stäubert C., Böselt I., Bohnekamp J., Römpler H., Enard W., Schöneberg T. Structural and functional evolution of the trace amine-associated receptors TAAR3, TAAR4 and TAAR5 in primates. PLoS ONE 2010, 5:e11133.
38. Strotmann J., Conzelmann S., Beck A., Feinstein P., Breer H., Mombaerts P. Local permutations in the glomerular array of the mouse olfactory bulb. J. Neurosci. 2000, 20:6927-6938.
39. Takahashi Y.K., Nagayama S., Mori K. Detection and masking of spoiled food smells by odor maps in the olfactory bulb. J. Neurosci. 2004, 24:8690-8694.
40. Tsuboi A., Miyazaki T., Imai T., Sakano H. Olfactory sensory neurons expressing class I odorant receptors converge their axons on an antero-dorsal domain of the olfactory bulb in the mouse. Eur. J. Neurosci. 2006, 23:1436-1444.
41. Vassalli A., Rothman A., Feinstein P., Zapotocky M., Mombaerts P. Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb. Neuron 2002, 35:681-696.
42. Vassalli A., Feinstein P., Mombaerts P. Homeodomain binding motifs modulate the probability of odorant receptor gene choice in transgenic mice. Mol. Cell. Neurosci. 2011, 46:381-396.
43. Vassar R., Chao S.K., Sitcheran R., Nuñez J.M., Vosshall L.B., Axel R. Topographic organization of sensory projections to the olfactory bulb. Cell 1994, 79:981-991.
44. Wachowiak M., Cohen L.B. Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron 2001, 32:723-735.
45. Wang F., Nemes A., Mendelsohn M., Axel R. Odorant receptors govern the formation of a precise topographic map. Cell 1998, 93:47-60.
46. Warming S., Costantino N., Court D.L., Jenkins N.A., Copeland N.G. Simple and highly efficient BAC recombineering using galK selection. Nucleic Acids Res. 2005, 33:e36.
47. Wood S.A., Allen N.D., Rossant J., Auerbach A., Nagy A. Non-injection methods for the production of embryonic stem cell-embryo chimaeras. Nature 1993, 365:87-89.
48. Wu S., Ying G., Wu Q., Capecchi M.R. Toward simpler and faster genome-wide mutagenesis in mice. Nat. Genet. 2007, 39:922-930.
49. Zhang X., Firestein S. The olfactory receptor gene superfamily of the mouse. Nat. Neurosci. 2002, 5:124-133.
50. Zhang X., Firestein S. Genomics of olfactory receptors. Results Probl. Cell Differ. 2009, 47:25-36.
51. Zhang X., Rogers M., Tian H., Zhang X., Zou D.J., Liu J., Ma M., Shepherd G.M., Firestein S.J. High-throughput microarray detection of olfactory receptor gene expression in the mouse. Proc. Natl. Acad. Sci. USA 2004, 101:14168-14173.
52. Zhao H., Ivic L., Otaki J.M., Hashimoto M., Mikoshiba K., Firestein S. Functional expression of a mammalian odorant receptor. Science 1998, 279:237-242.
53. Zucchi R., Chiellini G., Scanlan T.S., Grandy D.K. Trace amine-associated receptors and their ligands. Br. J. Pharmacol. 2006, 149:967-978.