Biogenic amines activate blood leukocytes via trace amine-associated receptors TAAR1 and TAAR2

Journal of Leukocyte Biology

Volumn 93, Issue 3, 2013, Pages 387-394

  Babusyte, Agne ^a   Kotthoff, Matthias ^a   Fiedler, Julia ^a   Krautwurst, Dietmar ^a  

^a DEUTSCHE FORSCHUNGSANSTALT FÜR LEBENSMITTELCHEMIE   (Germany)

Author keywords

Cytokines; Dimers; GPCR; Immune response; Olfactory receptors; siRNA

Indexed keywords

AMINE; BIOGENIC AMINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 9; MESSENGER RNA; RANTES; TRACE AMINE ASSOCIATED RECEPTOR 1; TRACE AMINE ASSOCIATED RECEPTOR 2; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ARTICLE; B LYMPHOCYTE; CELL MIGRATION; CONTROLLED STUDY; EFFECTOR CELL; HELPER CELL; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNOGLOBULIN PRODUCTION; LYMPHOCYTE FUNCTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH2 CELL;

ANTIBODIES; BIOGENIC AMINES; CHEMOKINE CCL5; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84874540133     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0912433     Document Type: Article

References (41)

1. Hellstrand, K., Asea, A., Hermodsson, S. (1994) Histaminergic regulation of antibody-dependent cellular cytotoxicity of granulocytes, monocytes, and natural killer cells. J. Leukoc. Biol. 55, 392-397.
2. Berry, M. D. (2004) Mammalian central nervous system trace amines. Pharmacologic amphetamines, physiologic neuromodulators. J. Neurochem. 90, 257-271.
3. Cloez-Tayarani, I., Changeux, J. P. (2007) Nicotine and serotonin in immune regulation and inflammatory processes: a perspective. J. Leukoc. Biol. 81, 599-606. Epub 2006 Nov 15.
4. Granvogl, M., Bugan, S., Schieberle, P. (2006) Formation of amines and aldehydes from parent amino acids during thermal processing of cocoa and model systems: new insights into pathways of the strecker reaction. J. Agric. Food Chem. 54, 1730-1739.
5. Karovicova, J., Kohajdova, Z. (2005) Biogenic amines in food. Chem. Pap. 59, 70-79.
6. Borowsky, B., Adham, N., Jones, K. A., Raddatz, R., Artymyshyn, R., Ogozalek, K. L., Durkin, M. M., Lakhlani, P. P., Bonini, J. A., Pathirana, S., Boyle, N., Pu, X., Kouranova, E., Lichtblau, H., Ochoa, F. Y., Branchek, T. A., Gerald, C. (2001) Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc. Natl. Acad. Sci. USA 98, 8966-8971.
7. Boulton, A. A. (1984) Trace amines and the neurosciences. In Neurobiology of the Trace Amines (A. Boulton, A. B. Baker, G. G. Dewhurst, W. Sandler, M., eds.), Human, Clifton, NJ, USA, 13-24.
8. Bunzow, J. R., Sonders, M. S., Arttamangkul, S., Harrison, L. M., Zhang, G., Quigley, D. I., Darland, T., Suchland, K. L., Pasumamula, S., Kennedy, J. L., Olson, S. B., Magenis, R. E., Amara, S. G., Grandy, D. K. (2001) Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor. Mol. Pharmacol. 60, 1181-1188.
9. Scanlan, T. S., Suchland, K. L., Hart, M. E., Chiellini, G., Huang, Y., Kruzich, P. J., Frascarelli, S., Crossley, D. A., Bunzow, J. R., Ronca-Testoni, S., Lin, E. T., Hatton, D., Zucchi, R., Grandy, D. K. (2004) 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone. Nat. Med. 10, 638-642.
10. D'Andrea, G., Terrazzino, S., Fortin, D., Farruggio, A., Rinaldi, L., Leon, A. (2003) HPLC electrochemical detection of trace amines in human plasma and platelets and expression of mRNA transcripts of trace amine receptors in circulating leukocytes. Neurosci. Lett. 346, 89-92.
11. Hoefig, C. S., Kohrle, J., Brabant, G., Dixit, K., Yap, B., Strasburger, C. J., Wu, Z. (2011) Evidence for extrathyroidal formation of 3-iodothyronamine in humans as provided by a novel monoclonal antibody-based chemiluminescent serum immunoassay. J. Clin. Endocrinol. Metab. 96, 1864-1872.
12. Miura, Y. (2000) Plasma β-phenylethylamine in Parkinson's disease. Kurume Med. J. 47, 267-272.
13. Chiellini, G., Frascarelli, S., Ghelardoni, S., Carnicelli, V., Tobias, S. C., DeBarber, A., Brogioni, S., Ronca-Testoni, S., Cerbai, E., Grandy, D. K., Scanlan, T. S., Zucchi, R. (2007) Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function. FASEB J. 21, 1597-1608.
14. Fehler, M., Broadley, K. J., Ford, W. R., Kidd, E. J. (2010) Identification of trace-amine-associated receptors (TAAR) in the rat aorta and their role in vasoconstriction by β-phenylethylamine. Naunyn Schmiedebergs Arch. Pharmacol. 382, 385-398.
15. Lindemann, L., Ebeling, M., Kratochwil, N. A., Bunzow, J. R., Grandy, D. K., Hoener, M. C. (2005) Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. Genomics 85, 372-385.
16. Miller, G. M. (2011) The emerging role of trace amine-associated receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity. J. Neurochem. 116, 164-176.
17. Fleischer, J., Schwarzenbacher, K., Breer, H. (2007) Expression of trace amine-associated receptors in the Grueneberg ganglion. Chem. Senses 32, 623-631.
18. Liberles, S. D., Buck, L. B. (2006) A second class of chemosensory receptors in the olfactory epithelium. Nature 442, 645-650.
19. Hussain, A., Saraiva, L. R., Korsching, S. I. (2009) Positive Darwinian selection and the birth of an olfactory receptor clade in teleosts. Proc. Natl. Acad. Sci. USA 106, 4313-4318.
20. Ferrero, D. M., Wacker, D., Roque, M. A., Baldwin, M. W., Stevens, R. C., Liberles, S. D. (2012) Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity. ACS Chem. Biol. 7, 1184-1189.
21. Ito, J., Ito, M., Nambu, H., Fujikawa, T., Tanaka, K., Iwaasa, H., Tokita, S. (2009) Anatomical and histological profiling of orphan G-proteincoupled receptor expression in gastrointestinal tract of C57BL/6J mice. Cell Tissue Res. 338, 257-269.
22. Zucchi, R., Chiellini, G., Scanlan, T. S., Grandy, D. K. (2006) Trace amine-associated receptors and their ligands. Br. J. Pharmacol. 149, 967-978.
23. Nelson, D. A., Tolbert, M. D., Singh, S. J., Bost, K. L. (2007) Expression of neuronal trace amine-associated receptor (TAAR) mRNAs in leukocytes. J. Neuroimmunol. 192, 21-30.
24. Panas, M. W., Xie, Z., Panas, H. N., Hoener, M. C., Vallender, E. J., Miller, G. M. (2012) Trace amine associated receptor 1 signaling in activated lymphocytes. J Neuroimmune Pharmacol. 7, 866-876.
25. Wasik, A. M., Millan, M. J., Scanlan, T., Barnes, N. M., Gordon, J. (2011) Evidence for functional trace amine associated receptor-1 in normal and malignant B cells. Leukemia Res. 36, 245-249.
26. Whale, T. A., Wilson, H. L., Tikoo, S. K., Babiuk, L. A., Griebel, P. J. (2006) Pivotal Advance: Passively acquired membrane proteins alter the functional capacity of bovine polymorphonuclear cells. J. Leukoc. Biol. 80, 481-491.
27. Amulic, B., Cazalet, C., Hayes, G. L., Metzler, K. D., Zychlinsky, A. (2012) Neutrophil function: from mechanisms to disease. Ann. Rev. Immunol. 30, 459-489.
28. Hall, R. A. (2005) Co-immunoprecipitation as a strategy to evaluate receptor-receptor or receptor-protein interactions. In G Protein-Coupled Receptor-Protein Interactions. (R. George, S. F. Dowd, eds.), B. John Wiley & Sons, Hoboken, NJ, USA, 165-178.
29. Barnes, P. J. (2011) Pathophysiology of allergic inflammation. Immunol. Rev. 242, 31-50.
30. Prescott, V. E., Forbes, E., Foster, P. S., Matthaei, K., Hogan, S. P. (2006) Mechanistic analysis of experimental food allergen-induced cutaneous reactions. J. Leukoc. Biol. 80, 258-266.
31. Tan, H. P., Lebeck, L. K., Nehlsen-Cannarella, S. L. (1992) Regulatory role of cytokines in IgE-mediated allergy. J. Leukoc. Biol. 52, 115-118.
32. Paul, W. E., Zhu, J. (2010) How are T(H)2-type immune responses initiated and amplified? Nat. Rev. Immunol. 10, 225-235.
33. Hershey, G. K., Friedrich, M. F., Esswein, L. A., Thomas, M. L., Chatila, T. A. (1997) The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor. N. Engl. J. Med. 337, 1720-1725.
34. McCoy, K. D., Harris, N. L., Diener, P., Hatak, S., Odermatt, B., Hangartner, L., Senn, B. M., Marsland, B. J., Geuking, M. B., Hengartner, H., Macpherson, A. J., Zinkernagel, R. M. (2006) Natural IgE production in the absence of MHC class II cognate help. Immunity 24, 329-339.
35. Jin, H., Malek, T. R. (2006) Redundant and unique regulation of activated mouse B lymphocytes by IL-4 and IL-21. J. Leukoc. Biol. 80, 1416-1423.
36. Mitchison, N. A. (2004) T-cell-B-cell cooperation. Nat. Rev. Immunol. 4, 308-312.
37. Clemmensen, S. N., Bohr, C. T., Rorvig, S., Glenthoj, A., Mora-Jensen, H., Cramer, E. P., Jacobsen, L. C., Larsen, M. T., Cowland, J. B., Tanassi, J. T., Heegaard, N. H., Wren, J. D., Silahtaroglu, A. N., Borregaard, N. (2012) Olfactomedin 4 defines a subset of human neutrophils. J. Leukoc. Biol. 91, 495-500.
38. Pillay, J., Kamp, V. M., van Hoffen, E., Visser, T., Tak, T., Lammers, J. W., Ulfman, L. H., Leenen, L. P., Pickkers, P., Koenderman, L. (2012) A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J. Clin. Invest. 122, 327-336.
39. Appay, V., Rowland-Jones, S. L. (2001) RANTES: a versatile and controversial chemokine. Trends Immunol. 22, 83-87.
40. Ashkar, S., Weber, G. F., Panoutsakopoulou, V., Sanchirico, M. E., Jansson, M., Zawaideh, S., Rittling, S. R., Denhardt, D. T., Glimcher, M. J., Cantor, H. (2000) Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science 287, 860-864.
41. Shalaby, A. R. (1996) Significance of biogenic amines to food safety and human health. Food Res. Int. 29, 675-690.